PIPA588149

BRCA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588149-Each-of-1 In Stock ₹ 44,277.30

PIPA588149 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

BRCA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BRCA1

Gene Alias

brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

672

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.34 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P38398

Gene Symbols

BRCA1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 901-1000 of human BRCA1 (NP_0092251)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: MCF7, HeLa, NIH/3T3, Mouse lung; Cellular Location: Chromosome, Cytoplasm, Cytoplasm, Nucleus Immunogen sequence: RIPPLFPIKS FVKTK BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor in combination with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC (for BRCA1 associated genome surveillance complex)
  • BRCA1 associates with RNA polymerase II, and through the C terminal domain, also interacts with histone deacetylase complex
  • The BRCA1 protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA588149

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Antigen:
BRCA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 901-1000 of human BRCA1 (NP_0092251)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588150

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Antigen:
TRIF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TICAM1

Gene Alias:
AW046014, AW547018, hCG_39321, HSD34, IIAE6, MyD88-3, Proline-rich, vinculin and TIR domain-containing protein B, PRVTIRB, Putative NF-kappa-B-activating protein 502H, RNF36, TI, Ticam1, TICAM-1, TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter molecule 1, TIR domain-containing adapter protein inducing IFN-beta, TIR domain-containing adaptor inducing interferon-beta, TIR-domain containing adaptor inducing interferon-beta, toll like receptor adaptor molecule 1, toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta, toll-interleukin I receptor domain containing adaptor molecule 1, toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, toll-like receptor adaptor molecule 1, TRIF

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106759, 148022, 363328

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.58 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q80UF7, Q8IUC6

Gene Symbols:
TICAM1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-280 of human TRIF / TICAM1 (NP_8915491)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588151

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Antigen:
TPM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPM1

Gene Alias:
AA986836, AI854628, alpha tropomyosin, alpha tropomyosin of brain, alpha tropomyosin of fibroblasts F2, alpha-fTM, Alpha-tm, alpha-Tm-1, alpha-Tm-2 isoform, alpha-tropomyosin, alpha-tropomyosin (partial), alpha-tropomyosin 1, alpha-tropomyosin 2, alpha-tropomyosin of skeletal fast muscle, C15orf13, cardiac alpha tropomyosin, cardiomyopathy, hypertrophic 3, CMD1Y, CMH3, epididymis secretory protein Li 265, HEL-S-265, hepatoma alpha tropomyosin, HTM-alpha, LVNC9, sarcomeric tropomyosin kappa, smooth muscle alpha-tropomyosin, striated muscle alpha-tropomyosin, Tm1, TM2, Tm3, Tma2, Tmpa, Tmsa, Tpm1, Tpm-1, tpm1 protein, TPM1-1, TPM1-alpha, TPMA, tropomyosin, tropomyosin (CTm4), tropomyosin (CTm7), tropomyosin 1, tropomyosin 1 (alpha), tropomyosin 1 alpha chain, tropomyosin 1, alpha, tropomyosin 1-1, tropomyosin 3 alpha, tropomyosin alpha-1 chain, Tropomyosin-1, unnamed protein product, zgc:171719, zgc:55951, zgc:77009

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22003, 7168

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P09493, P58771

Gene Symbols:
TPM1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human Tropomyosin 1 (NP_0010180081)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588152

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Antigen:
CHD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHD4

Gene Alias:
9530019N15Rik, AA617397, ATP-dependent helicase CHD4, BC005710, Chd4, CHD-4, chromodomain helicase DNA binding protein 4, chromodomain-helicase-DNA-binding protein 4, D6Ertd380e, Mi-2, Mi-2 autoantigen, Mi-2 autoantigen 218 kDa protein, Mi-2 beta, MI2B, Mi-2b, Mi-2beta, Mi2-BETA, mKIAA4075

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107932, 1108, 117535

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.78 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q14839, Q6PDQ2

Gene Symbols:
CHD4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_0012642)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG