PIPA588298

TAK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588298-Each-of-1 In Stock ₹ 44,705.10

PIPA588298 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TAK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K7

Gene Alias

B430101B05, C87327, hypothetical protein LOC553788, I79_000697, M3K7, map3k7, map3k7.L, MAPKKK, MEKK7, mitogen activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7 L homeolog, RP1-154G14.1, si:ch211-225h9.1, Tak1, TAK1z, TGF1a, TGF-beta activated kinase 1, TGF-beta-activated kinase 1, TGF-beta-activated kinase TAK1, transforming growth factor beta-activated kinase 1, transforming growth factor-beta-activated kinase 1, XELAEV_18027270mg, xTAK1, zgc:110612

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26409, 313121, 6885

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.28 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

O43318, P0C8E4, Q62073

Gene Symbols

MAP3K7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 110-325 of human TAK1 (NP_6633041)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GSLYNVLHGA EPLPYYTAAH AMSWCLQCSQ GVAYLHSMQP KALIHRDLKP PNLLLVAGGT VLKICDFGTA CDIQTHMTNN KGSAAWMAPE VFEGSNYSEK CDVFSWGIIL WEVITRRKPF DEIGGPAFRI MWAVHNGTRP PLIKNLPKPI ESLMTRCWSK DPSQRPSMEE IVKIMTHLMR YFPGADEPLQ YPCQYSDEGQ SNSATSTGSF MDIAST Positive Samples: Jurkat, K-562, Mouse liver, Mouse kidney; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
  • Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
  • It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
  • Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
  • TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
  • Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
  • In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
  • Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA588298

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Antigen:
TAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05, C87327, hypothetical protein LOC553788, I79_000697, M3K7, map3k7, map3k7.L, MAPKKK, MEKK7, mitogen activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7 L homeolog, RP1-154G14.1, si:ch211-225h9.1, Tak1, TAK1z, TGF1a, TGF-beta activated kinase 1, TGF-beta-activated kinase 1, TGF-beta-activated kinase TAK1, transforming growth factor beta-activated kinase 1, transforming growth factor-beta-activated kinase 1, XELAEV_18027270mg, xTAK1, zgc:110612

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26409, 313121, 6885

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O43318, P0C8E4, Q62073

Gene Symbols:
MAP3K7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-325 of human TAK1 (NP_6633041)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588300

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Antigen:
GLG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLG1

Gene Alias:
AI593353, AW537898, CFR, CFR1, CFR-1, Cysteine-rich fibroblast growth factor receptor, E-selectin ligand 1, ESL1, ESL-1, Glg1, Golgi apparatus protein 1, golgi glycoprotein 1, golgi sialoglycoprotein MG-160, MG160, MG-160, selectin, endothelial cell, ligand, Selel

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20340, 2734

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.39 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q61543, Q92896

Gene Symbols:
GLG1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 974-1203 of human GLG1 (NP_0363332)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588304

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Antigen:
MYH10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYH10

Gene Alias:
5730504C04Rik, 9330167F11Rik, cellular myosin heavy chain, type B, flectin, Fltn, MCH-B, MCH-B(B2), mKIAA3005, MYH10, Myhn2, Myhn-2, Myosin heavy chain 10, myosin heavy chain 10, non-muscle, myosin heavy chain, non-muscle IIb, myosin heavy chain, nonmuscle type B, myosin heavy chain, nonmuscular, type B, myosin IIB, myosin, heavy chain 10, non-muscle, myosin, heavy polypeptide 10, non-muscle, myosin-10, NMHC II-B, NMHC-B, NMHCII-B, NMMHC IIB, NMMHC II-b, NMMHCB, NMMHC-B, NMMHC-IIB, nonmuscle myosin, Non-muscle myosin heavy chain B, nonmuscle myosin heavy chain IIB, non-muscle myosin heavy chain IIb, nonmuscle myosin heavy chain II-B, nonmuscle myosin heavy chain-B, nonmuscle myosin II heavy chain-B, OTTHUMP00000165799, SMemb

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4628, 77579, 79433

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.41 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P35580, Q61879, Q9JLT0

Gene Symbols:
MYH10

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1908-2007 of human MYH10 (NP_0012429411)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588305

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Antigen:
RASSF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RASSF1

Gene Alias:
123F protein, 123F2, AA536941, AU044980, cardiac-specific ras association domain family 1 protein, NORE2A, pancreas-specific ras association domain family 1 protein, protein 123F2, Ras association (RalGDS/AF-6) domain family 1, Ras association (RalGDS/AF-6) domain family member 1, Ras association domain family 1, Ras association domain family member 1, ras association domain-containing protein 1, Rassf1, Rassf1A, RASSF1A tumor suppressor, Rassf1B, Rassf1C, RDA32, REH3P21, tumor suppressor protein RDA32, wu:fc17f02, WUGSC:H_LUCA12.5, zgc:112224, zgc:92505, zgc:92505 protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11186

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9NS23

Gene Symbols:
RASSF1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1 (NP_0091133)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG