PIPA588380
DTL Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588380-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588380 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
DTL
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DTL
Gene Alias
2810047L02Rik, 5730564G15Rik, CDT2, CDW1, DCAF2, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, denticleless E3 ubiquitin protein ligase homolog, denticleless E3 ubiquitin protein ligase homolog (Drosophila), denticleless homolog, denticleless homolog (Drosophila), denticleless protein homolog, DTL, L2dtl, lethal(2) denticleless protein homolog, Meth A RAMP, Meth A retinoic acid-regulated nuclear matrix-associated protein, RA regulated nuclear matrix associated protein, RAMP, RA-regulated nuclear matrix-associated protein, Retinoic acid-regulated nuclear matrix-associated protein, RGD1310439
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
305073, 76843
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.52 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q3TLR7
Gene Symbols
DTL
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 541-730 of human DTL (NP_0575323)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AEACSESRNR VKRRLDSSCL ESVKQKCVKS CNCVTELDGQ VENLHLDLCC LAGNQEDLSK DSLGPTKSSK IEGAGTSISE PPSPISPYAS ESCGTLPLPL RPCGEGSEMV GKENSSPENK NWLLAMAAKR KAENPSPRSP SSQTPNSRRQ SGKTLPSPVT ITPSSMRKIC TYFHRKSQED FCGPEHSTEL; Positive Samples: Mouse testis, Mouse liver, Rat brain; Cellular Location: Chromosome, Cytoplasm, Nucleoplasmic side, Nucleus, Nucleus membrane, Peripheral membrane protein, centrosome, cytoskeleton, microtubule organizing center Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis
- The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1)
- CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication
- CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing
- Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation
- In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
Compare Similar Items
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Antigen: DTL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DTL
Gene Alias: 2810047L02Rik, 5730564G15Rik, CDT2, CDW1, DCAF2, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, denticleless E3 ubiquitin protein ligase homolog, denticleless E3 ubiquitin protein ligase homolog (Drosophila), denticleless homolog, denticleless homolog (Drosophila), denticleless protein homolog, DTL, L2dtl, lethal(2) denticleless protein homolog, Meth A RAMP, Meth A retinoic acid-regulated nuclear matrix-associated protein, RA regulated nuclear matrix associated protein, RAMP, RA-regulated nuclear matrix-associated protein, Retinoic acid-regulated nuclear matrix-associated protein, RGD1310439
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 305073, 76843
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.52 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q3TLR7
Gene Symbols: DTL
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 541-730 of human DTL (NP_0575323)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DTL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DTL
Gene Alias:
2810047L02Rik, 5730564G15Rik, CDT2, CDW1, DCAF2, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, denticleless E3 ubiquitin protein ligase homolog, denticleless E3 ubiquitin protein ligase homolog (Drosophila), denticleless homolog, denticleless homolog (Drosophila), denticleless protein homolog, DTL, L2dtl, lethal(2) denticleless protein homolog, Meth A RAMP, Meth A retinoic acid-regulated nuclear matrix-associated protein, RA regulated nuclear matrix associated protein, RAMP, RA-regulated nuclear matrix-associated protein, Retinoic acid-regulated nuclear matrix-associated protein, RGD1310439
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
305073, 76843
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.52 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q3TLR7
Gene Symbols:
DTL
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 541-730 of human DTL (NP_0575323)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LILRB2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LILRB2
Gene Alias: CD85 antigen-like family member D, CD85D, CD85d antigen, Ig-like transcript 4, ILT4, ILT-4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin like receptor B2, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3, LILRB2, Lilrb3, LIR2, LIR-2, LIR2CD85D, MIR10, MIR-10, MIR10LILRA6, monocyte/macrophage immunoglobulin-like receptor 10, myeloid inhibitory receptor 10, Neutrophil immunoglobulin-like receptor 1, Nilr1, NILR-1, paired-Ig-like receptor B, Pirb, type 1 one-pass transmembrane Ig-like receptor
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10288
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.15 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q8N423
Gene Symbols: LILRB2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 479-598 of human LILRB2/CD85d/ILT4 (NP_0058653)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LILRB2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LILRB2
Gene Alias:
CD85 antigen-like family member D, CD85D, CD85d antigen, Ig-like transcript 4, ILT4, ILT-4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin like receptor B2, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3, LILRB2, Lilrb3, LIR2, LIR-2, LIR2CD85D, MIR10, MIR-10, MIR10LILRA6, monocyte/macrophage immunoglobulin-like receptor 10, myeloid inhibitory receptor 10, Neutrophil immunoglobulin-like receptor 1, Nilr1, NILR-1, paired-Ig-like receptor B, Pirb, type 1 one-pass transmembrane Ig-like receptor
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10288
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.15 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q8N423
Gene Symbols:
LILRB2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 479-598 of human LILRB2/CD85d/ILT4 (NP_0058653)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NMB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NMB
Gene Alias: 3110023K12Rik, neuromedin B, neuromedin-B, Neuromedin-B-32, neuromedin-beta, NMB, RGD1562710
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4828, 499194, 68039
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.29 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P08949, Q9CR53
Gene Symbols: NMB
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human NMB (NP_0665632)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NMB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NMB
Gene Alias:
3110023K12Rik, neuromedin B, neuromedin-B, Neuromedin-B-32, neuromedin-beta, NMB, RGD1562710
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4828, 499194, 68039
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.29 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P08949, Q9CR53
Gene Symbols:
NMB
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human NMB (NP_0665632)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SNRPA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SNRPA1
Gene Alias: 1500015N06Rik, Lea1, small nuclear ribonucleoprotein polypeptide A', Snrpa1, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein polypeptide A', U2 snRNP A', U2 snRNP-A'
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100361269, 6627, 68981
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.69 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P09661, P57784
Gene Symbols: SNRPA1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SNRPA1 (NP_0030812)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SNRPA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SNRPA1
Gene Alias:
1500015N06Rik, Lea1, small nuclear ribonucleoprotein polypeptide A', Snrpa1, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein polypeptide A', U2 snRNP A', U2 snRNP-A'
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100361269, 6627, 68981
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.69 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P09661, P57784
Gene Symbols:
SNRPA1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SNRPA1 (NP_0030812)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG