PIPA588439
SHARPIN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588439-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588439 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SHARPIN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SHARPIN
Gene Alias
0610041B22Rik, AW121341, Conneck1, cpdm, hSIPL1, mSIPL1, protein kinase C-interacting protein RBCC like 1, PSEC0216, RBCKL1, SHANK associated RH domain interactor, SHANK-associated RH domain interacting protein, SHANK-associated RH domain interactor, shank-associated RH domain-interacting protein, shank-interacting protein, shank-interacting protein-like 1, SHARPIN, SIPL1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
106025, 81858, 81859
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.08 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
Q91WA6, Q9EQL9, Q9H0F6
Gene Symbols
SHARPIN
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human SHARPIN (NP_1122363?)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 293T, LO2, HeLa, A-549, Rat brain; Cellular Location: Cell junction, Cytoplasm, cytosol, synapse Immunogen sequence: MAPPAGGAAA AASDLGSAAV LLAVHAAVRP LGAGPDAEAQ LRRLQLSADP ERPGRFRLEL LGAGPGAVNL EWPLESVSYT IRGPTQHELQ PPPGGPGTLS LHFLNPQEAQ RWAVLVRGAT VEGQNG Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
- LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
- Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
- LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
- Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.
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Antigen: SHARPIN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SHARPIN
Gene Alias: 0610041B22Rik, AW121341, Conneck1, cpdm, hSIPL1, mSIPL1, protein kinase C-interacting protein RBCC like 1, PSEC0216, RBCKL1, SHANK associated RH domain interactor, SHANK-associated RH domain interacting protein, SHANK-associated RH domain interactor, shank-associated RH domain-interacting protein, shank-interacting protein, shank-interacting protein-like 1, SHARPIN, SIPL1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 106025, 81858, 81859
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.08 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q91WA6, Q9EQL9, Q9H0F6
Gene Symbols: SHARPIN
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human SHARPIN (NP_1122363?)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHARPIN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SHARPIN
Gene Alias:
0610041B22Rik, AW121341, Conneck1, cpdm, hSIPL1, mSIPL1, protein kinase C-interacting protein RBCC like 1, PSEC0216, RBCKL1, SHANK associated RH domain interactor, SHANK-associated RH domain interacting protein, SHANK-associated RH domain interactor, shank-associated RH domain-interacting protein, shank-interacting protein, shank-interacting protein-like 1, SHARPIN, SIPL1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
106025, 81858, 81859
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.08 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q91WA6, Q9EQL9, Q9H0F6
Gene Symbols:
SHARPIN
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human SHARPIN (NP_1122363?)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: VRK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VRK2
Gene Alias: 2810003O05Rik, AI447698, Serine/threonine-protein kinase VRK2, vaccinia related kinase 2, vaccinia virus B1R-related kinase 2, vaccinia virus BIR kinase related kinase 2, vaccinia-related kinase 2, Vrk2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7444
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.71 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q86Y07
Gene Symbols: VRK2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 269-508 of human VRK2 (NP_0062872)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
VRK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VRK2
Gene Alias:
2810003O05Rik, AI447698, Serine/threonine-protein kinase VRK2, vaccinia related kinase 2, vaccinia virus B1R-related kinase 2, vaccinia virus BIR kinase related kinase 2, vaccinia-related kinase 2, Vrk2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7444
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.71 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q86Y07
Gene Symbols:
VRK2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 269-508 of human VRK2 (NP_0062872)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GABRA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GABRA1
Gene Alias: ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14394
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 3.55 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P62812
Gene Symbols: GABRA1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-251 of human GABRA1 (NP_0007972)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
GABRA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GABRA1
Gene Alias:
ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14394
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
3.55 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P62812
Gene Symbols:
GABRA1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-251 of human GABRA1 (NP_0007972)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PCPTP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRR
Gene Alias: Ch-1 PTPase, ch-1PTPase, ECPPT, ECPTP, EC-PTP, Gmcp1, mPTP213, NC-PTPCOM1, PC12-PTP1, PCPTP1, Phosphotyrosine phosphatase 13, protein tyrosine phosphatase Cr1PTPase, protein tyrosine phosphatase PCPTP1, protein tyrosine phosphatase, receptor type R, protein tyrosine phosphatase, receptor type, R, protein-tyrosine phosphatase NC-PTPCOM1, protein-tyrosine phosphatase PCPTP1, Protein-tyrosine-phosphatase SL, protein-tyrosine-phosphatase-SL, Ptp, Ptp13, PTPBR7, PTPRQ, PTPRR, PTP-SL, receptor-type tyrosine-protein phosphatase R, R-PTP-R, RPTPRR, STEP-like PTPase, tyrosine phosphatase CBPTP
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5801, 94202
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.91 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O08617, Q15256
Gene Symbols: PTPRR
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-227 of human PTPRR (NP_0028402)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PCPTP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRR
Gene Alias:
Ch-1 PTPase, ch-1PTPase, ECPPT, ECPTP, EC-PTP, Gmcp1, mPTP213, NC-PTPCOM1, PC12-PTP1, PCPTP1, Phosphotyrosine phosphatase 13, protein tyrosine phosphatase Cr1PTPase, protein tyrosine phosphatase PCPTP1, protein tyrosine phosphatase, receptor type R, protein tyrosine phosphatase, receptor type, R, protein-tyrosine phosphatase NC-PTPCOM1, protein-tyrosine phosphatase PCPTP1, Protein-tyrosine-phosphatase SL, protein-tyrosine-phosphatase-SL, Ptp, Ptp13, PTPBR7, PTPRQ, PTPRR, PTP-SL, receptor-type tyrosine-protein phosphatase R, R-PTP-R, RPTPRR, STEP-like PTPase, tyrosine phosphatase CBPTP
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5801, 94202
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.91 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O08617, Q15256
Gene Symbols:
PTPRR
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-227 of human PTPRR (NP_0028402)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG