PIPA588458

AP2S1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588458-Each-of-1 In Stock ₹ 44,277.30

PIPA588458 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

AP2S1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AP2S1

Gene Alias

adapter-related protein complex 2 sigma subunit, adapter-related protein complex 2 subunit sigma, adaptor protein complex AP-2 subunit sigma, adaptor related protein complex 2 sigma 1 subunit, adaptor-related protein complex 2 sigma 1 subunit, adaptor-related protein complex 2 subunit sigma, adaptor-related protein complex 2, sigma 1 subunit, AI043088, Ap17, AP17-DELTA, AP-2 complex subunit sigma, AP2S1, Claps2, Clathrin assembly protein 2 sigma small chain, clathrin assembly protein 2 small chain, clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, clathrin-associated protein 17, clathrin-associated/assembly/adaptor protein, small 2 (17kD), FBH3, FBHOk, HA2 17 kDa subunit, HHC3, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, sigma-adaptin 3b

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1175, 232910, 65046

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.02 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P53680, P62743, P62744

Gene Symbols

AP2S1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human AP2S1 (NP_0040602)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MIRFILIQNR AGKTRLAKWY MQFDDDEKQK LIEEVHAVVT VRDAKHTNFV EFRNFKIIYR RYAGLYFCIC VDVNDNNLAY LEAIHNFVEV LNEYFHNVCE LDLVFNFYKV YTVVDEMFLA GEIRETSQTK VLKQLLMLQS LE; Positive Samples: HeLa, LO2, SH-SY5Y, Mouse brain, Mouse kidney, Mouse spleen, Rat brain, Rat spleen; Cellular Location: Cell membrane, Cytoplasmic side, Membrane, Peripheral membrane protein, coated pit Component of the adaptor protein complex 2 (AP-2)
  • Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways
  • Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation
  • AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome
  • The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components
  • Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation
  • AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis
  • AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface
  • AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules
  • AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway
  • The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif
  • May also play a role in extracellular calcium homeostasis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA588458

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Antigen:
AP2S1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP2S1

Gene Alias:
adapter-related protein complex 2 sigma subunit, adapter-related protein complex 2 subunit sigma, adaptor protein complex AP-2 subunit sigma, adaptor related protein complex 2 sigma 1 subunit, adaptor-related protein complex 2 sigma 1 subunit, adaptor-related protein complex 2 subunit sigma, adaptor-related protein complex 2, sigma 1 subunit, AI043088, Ap17, AP17-DELTA, AP-2 complex subunit sigma, AP2S1, Claps2, Clathrin assembly protein 2 sigma small chain, clathrin assembly protein 2 small chain, clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, clathrin-associated protein 17, clathrin-associated/assembly/adaptor protein, small 2 (17kD), FBH3, FBHOk, HA2 17 kDa subunit, HHC3, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, sigma-adaptin 3b

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1175, 232910, 65046

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.02 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P53680, P62743, P62744

Gene Symbols:
AP2S1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human AP2S1 (NP_0040602)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA588460

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Antigen:
PPIH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPIH

Gene Alias:
1100001J08Rik, 2010111B15Rik, 4833408F11Rik, AI464484, cyclophilin H, CYP20, CYP-20, CYPH, D4Wsu43e, peptidyl prolyl isomerase H, peptidyl-prolyl cis-trans isomerase H, peptidylprolyl isomerase H, peptidylprolyl isomerase H (cyclophilin H), PPIase h, Ppih, RGD1564921, Rotamase H, small nuclear ribonucleoprotein particle-specific cyclophilin H, SnuCyp-20, USA-CYP, USA-CyP SnuCyp-20, U-snRNP-associated cyclophilin SnuCyp-20, U-snRNP-associated cyclophilin SunCyp-20

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10465, 366461

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
4.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O43447

Gene Symbols:
PPIH

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of human PPIH (NP_0063381)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA588461

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Antigen:
TSNAX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSNAX

Gene Alias:
R74833, translin associated factor X, translin-associated factor X, Translin-associated protein X, translin-like protein, Trax, TSNAX

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53424, 7257

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q99598, Q9QZE7

Gene Symbols:
TSNAX

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TSNAX (NP_0059901)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA588462

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Antigen:
CD55

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD55

Gene Alias:
CD55, CD55 antigen, CD55 molecule (Cromer blood group), CD55 molecule, decay accelerating factor for complement, CD55 molecule, decay accelerating factor for complement (Cromer blood group), Cd55a, Complement decay-accelerating factor, complement decay-accelerating factor, GPI-anchored, complement-glycosylphosphatidylinositol, CR, CROM, Cromer blood group, Daf, Daf1, DAF-GPI, decay accelarating factor 1, decay accelerating factor 1, decay accelerating factor GPI-form, decay-accelarating factor, glycosylphophatidylinositol-anchored form, GPI anchor addition signal, GPI-DAF, RP11-357P18.1, TC

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13136, 1604, 64036

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P08174, Q61475

Gene Symbols:
CD55

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human CD55 (NP_0005651)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG