PIPA588595
SHH Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588595-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588595 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SHH
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Shh
Gene Alias
9530036O11Rik, Dsh, fc83d08, hedgehog, hemimelic extra toes, Hhg1, HHG-1, HLP3, HPE3, Hx, Hxl3, M100081, MCOPCB5, morphogen, shh, Shh N-terminal processed signaling domains, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, shh.L, shha, ShhN, ShhNC, ShhNp, short digits, SMMCI, sonic hedgehog, sonic hedgehog a, sonic hedgehog homolog, sonic hedgehog L homeolog, sonic hedgehog protein, Sonic hedgehog protein 19 kDa product, Sonic hedgehog protein A, Sonic hedgehog protein A N-product, Sonic hedgehog protein N-product, sonic hedgehog signaling molecule, sonic hedgehog signaling molecule a, sonic-you, syu, TPT, TPTPS, vhh1, vhh-1, wu:fc83d08, XELAEV_18030676mg, Xhh, xshh, X-SHH
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6469
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.41 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q15465
Gene Symbols
Shh
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 231-330 of human Sonic Hedgehog (Shh) (NP_0001841)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: A-549; Cellular Location: Cell membrane, Lipid-anchor, extracellular space Immunogen sequence: GRLLYSDFLT FLDRDDGAKK VFYVIETREP RERLLLTAAH LLFVAPHNDS ATGEPEASSG SGPPSGGALG PRALFASRVR PGQRVYVVAE RDGDRRLLPA Sonic Hedgehog (SHH), which is expressed only during embryogenesis, is instrumental in patterning the early embryo
- It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites
- Of three human proteins showing sequence and functional similarity to the Sonic Hedgehog protein of Drosophila, this protein is the most similar
- The protein is made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing
- More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo
- Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres
- HPE is manifested by facial deformities
- In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.
Compare Similar Items
Show Difference
Antigen: SHH
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shh
Gene Alias: 9530036O11Rik, Dsh, fc83d08, hedgehog, hemimelic extra toes, Hhg1, HHG-1, HLP3, HPE3, Hx, Hxl3, M100081, MCOPCB5, morphogen, shh, Shh N-terminal processed signaling domains, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, shh.L, shha, ShhN, ShhNC, ShhNp, short digits, SMMCI, sonic hedgehog, sonic hedgehog a, sonic hedgehog homolog, sonic hedgehog L homeolog, sonic hedgehog protein, Sonic hedgehog protein 19 kDa product, Sonic hedgehog protein A, Sonic hedgehog protein A N-product, Sonic hedgehog protein N-product, sonic hedgehog signaling molecule, sonic hedgehog signaling molecule a, sonic-you, syu, TPT, TPTPS, vhh1, vhh-1, wu:fc83d08, XELAEV_18030676mg, Xhh, xshh, X-SHH
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6469
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.41 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q15465
Gene Symbols: Shh
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 231-330 of human Sonic Hedgehog (Shh) (NP_0001841)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SHH
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Shh
Gene Alias:
9530036O11Rik, Dsh, fc83d08, hedgehog, hemimelic extra toes, Hhg1, HHG-1, HLP3, HPE3, Hx, Hxl3, M100081, MCOPCB5, morphogen, shh, Shh N-terminal processed signaling domains, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, shh.L, shha, ShhN, ShhNC, ShhNp, short digits, SMMCI, sonic hedgehog, sonic hedgehog a, sonic hedgehog homolog, sonic hedgehog L homeolog, sonic hedgehog protein, Sonic hedgehog protein 19 kDa product, Sonic hedgehog protein A, Sonic hedgehog protein A N-product, Sonic hedgehog protein N-product, sonic hedgehog signaling molecule, sonic hedgehog signaling molecule a, sonic-you, syu, TPT, TPTPS, vhh1, vhh-1, wu:fc83d08, XELAEV_18030676mg, Xhh, xshh, X-SHH
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6469
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.41 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q15465
Gene Symbols:
Shh
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 231-330 of human Sonic Hedgehog (Shh) (NP_0001841)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SLC1A4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC1A4
Gene Alias: Alanine/serine/cysteine/threonine transporter 1, ASCT1, ASCT-1, AW045657, glutamate/neutral amino acid transporter, neutral amino acid transporter A, neutral amino acid transporter ASCT1, OTTHUMP00000159933, OTTHUMP00000235138, SATT, si:zc101n13.5, Slc1a4, slc1a4 protein, sodium-dependent neutral amino acid transporter ASCT1, solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, solute carrier family 1 member 4, SPATCCM, zgc:92817
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 305540, 55963, 6509
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.62 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O35874, P43007
Gene Symbols: SLC1A4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human SLC1A4 (NP_0030292)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SLC1A4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC1A4
Gene Alias:
Alanine/serine/cysteine/threonine transporter 1, ASCT1, ASCT-1, AW045657, glutamate/neutral amino acid transporter, neutral amino acid transporter A, neutral amino acid transporter ASCT1, OTTHUMP00000159933, OTTHUMP00000235138, SATT, si:zc101n13.5, Slc1a4, slc1a4 protein, sodium-dependent neutral amino acid transporter ASCT1, solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, solute carrier family 1 member 4, SPATCCM, zgc:92817
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
305540, 55963, 6509
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.62 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O35874, P43007
Gene Symbols:
SLC1A4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human SLC1A4 (NP_0030292)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: JNK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPK9
Gene Alias: AI851083, c-Jun kinase 2, c-Jun N-terminal kinase 2, I79_012561, JNK, JNK/SAPK alpha, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, JNK-46, JNK-55, Jun kinase, MAP kinase 10, MAP kinase 8, MAP kinase 9, MAPK 10, MAPK 9, MAPK10, MAPK8, Mapk9, mitogen activated protein kinase 9, mitogen-activated protein kinase 9, OTTHUMP00000161542, OTTHUMP00000161543, p54a, p54-alpha, p54aSAPK, PRKM8, PRKM9, protein kinase, mitogen-activated 9, SAPK, SAPK1, SAPK1a, SAPK1c, SAPK-alpha, stress activated protein kinase alpha II, stress-activated protein kinase 1a, Stress-activated protein kinase JNK2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26420, 5601
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot, Immunohistochemistry, Western Blot
Concentration: 0.88 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P45984, Q9WTU6
Gene Symbols: MAPK9
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-424 of human JNK2 (NP_0027433)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
JNK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPK9
Gene Alias:
AI851083, c-Jun kinase 2, c-Jun N-terminal kinase 2, I79_012561, JNK, JNK/SAPK alpha, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, JNK-46, JNK-55, Jun kinase, MAP kinase 10, MAP kinase 8, MAP kinase 9, MAPK 10, MAPK 9, MAPK10, MAPK8, Mapk9, mitogen activated protein kinase 9, mitogen-activated protein kinase 9, OTTHUMP00000161542, OTTHUMP00000161543, p54a, p54-alpha, p54aSAPK, PRKM8, PRKM9, protein kinase, mitogen-activated 9, SAPK, SAPK1, SAPK1a, SAPK1c, SAPK-alpha, stress activated protein kinase alpha II, stress-activated protein kinase 1a, Stress-activated protein kinase JNK2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26420, 5601
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot, Immunohistochemistry, Western Blot
Concentration:
0.88 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P45984, Q9WTU6
Gene Symbols:
MAPK9
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-424 of human JNK2 (NP_0027433)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: UBE2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UBE2A
Gene Alias: E2 ubiquitin-conjugating enzyme A, hhr6a, HR6A, Mhr6a, mp:zf637-2-000771, MRXS30, MRXSN, RAD6 homolog A, Rad6a, si:bz46j2.4, UBC2, ube2a, ube2a.L, Ubiquitin carrier protein A, ubiquitin conjugating enzyme E2 A, ubiquitin conjugating enzyme E2 A L homeolog, ubiquitin conjugating enzyme E2 A L homeolog, ubiquitin conjugating enzyme E2A L homeolog, ubiquitin conjugating enzyme E2A, ubiquitin-conjugating enzyme E2 A, ubiquitin-conjugating enzyme E2A, ubiquitin-conjugating enzyme E2A (RAD6 homolog), ubiquitin-conjugating enzyme E2A, RAD6 homolog, ubiquitin-conjugating enzyme HR6A, ubiquitin-protein ligase A, wu:fa01h11, XELAEV_18038882mg
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22209, 7319
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P49459, Q9Z255
Gene Symbols: UBE2A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human UBE2A (NP_0033272)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
UBE2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UBE2A
Gene Alias:
E2 ubiquitin-conjugating enzyme A, hhr6a, HR6A, Mhr6a, mp:zf637-2-000771, MRXS30, MRXSN, RAD6 homolog A, Rad6a, si:bz46j2.4, UBC2, ube2a, ube2a.L, Ubiquitin carrier protein A, ubiquitin conjugating enzyme E2 A, ubiquitin conjugating enzyme E2 A L homeolog, ubiquitin conjugating enzyme E2 A L homeolog, ubiquitin conjugating enzyme E2A L homeolog, ubiquitin conjugating enzyme E2A, ubiquitin-conjugating enzyme E2 A, ubiquitin-conjugating enzyme E2A, ubiquitin-conjugating enzyme E2A (RAD6 homolog), ubiquitin-conjugating enzyme E2A, RAD6 homolog, ubiquitin-conjugating enzyme HR6A, ubiquitin-protein ligase A, wu:fa01h11, XELAEV_18038882mg
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22209, 7319
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P49459, Q9Z255
Gene Symbols:
UBE2A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human UBE2A (NP_0033272)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG