PIPA588606
COX2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588606-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588606 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
COX2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGS2
Gene Alias
COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19225, 29527, 5743
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Western Blot
Concentration
2.72 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
P35354, P35355, Q05769
Gene Symbols
PTGS2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of COX2/PTGS2 (NP_0009541)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: A-549, HeLa, Mouse spleen, Mouse lung, Rat lung, Rat kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein Immunogen sequence: PLLPDTFQIH DQKYNYQQFI YNNSILLEHG ITQFVESFTR QIAGRVAGGR NVPPAVQKVS QASIDQSRQM KYQSFNEYRK RFMLKPYESF EELTGEKEMS AELEALYGDI DAVELYPALL VEKPRPDAIF GETMVEVGAP FSLKGLMGNV ICSPAYWKPS TFGGEVGFQI INTASIQSLI CNNVKGCPFT SFSVPDPELI KTVTINASSS RSGLDDINPT VLLKERSTEL COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
- The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
- It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
- Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
- In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
- COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
- Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
- COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.
Compare Similar Items
Show Difference
Antigen: COX2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTGS2
Gene Alias: COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19225, 29527, 5743
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Western Blot
Concentration: 2.72 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P35354, P35355, Q05769
Gene Symbols: PTGS2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of COX2/PTGS2 (NP_0009541)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
COX2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTGS2
Gene Alias:
COII, COX2, Cox-2, COXII, cyclooxygenase, cyclooxygenase 2, cyclooxygenase 2b, cyclooxygenase-2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, hCox-2, Macrophage activation-associated marker protein P71/73, mitochondrially encoded cytochrome c oxidase II, MTCO2, MT-CO2, PES-2, PGG/HS, PGH synthase 2, Pghs2, PGHS-2, Pghs-b, PHS II, PHS-2, prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Ptgs2, Tis10, TIS10 protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19225, 29527, 5743
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Western Blot
Concentration:
2.72 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P35354, P35355, Q05769
Gene Symbols:
PTGS2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of COX2/PTGS2 (NP_0009541)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SLC30A1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Slc30a1
Gene Alias: AI839647, C130040I11Rik, Slc30a1, solute carrier family 30 (zinc transporter), member 1, solute carrier family 30 member 1, solute carrier family 30, member 1, zinc transporter 1, ZNT1, ZnT-1, ZnT-1 zinc transporter, ZRC1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22782, 58976
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.97 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q60738, Q62720
Gene Symbols: Slc30a1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 328-507 of human SLC30A1 (NP_0670172)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SLC30A1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Slc30a1
Gene Alias:
AI839647, C130040I11Rik, Slc30a1, solute carrier family 30 (zinc transporter), member 1, solute carrier family 30 member 1, solute carrier family 30, member 1, zinc transporter 1, ZNT1, ZnT-1, ZnT-1 zinc transporter, ZRC1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22782, 58976
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.97 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q60738, Q62720
Gene Symbols:
Slc30a1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 328-507 of human SLC30A1 (NP_0670172)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SRSF9
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SRSF9
Gene Alias: 25kDa, 2610029M16Rik, hypothetical protein zgc:77449, LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 9, pre-mRNA-splicing factor SRp30C, serine and arginine rich splicing factor 9, serine/arginine-rich splicing factor 9, Sfrs9, splicing factor, arginine/serine rich 9, splicing factor, arginine/serine-rich 9, SR splicing factor 9, SRP30C, Srsf9, zgc:77449
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 108014, 8683
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 0.65 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q13242, Q9D0B0
Gene Symbols: SRSF9
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human SFRS9 (NP_0037601)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SRSF9
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SRSF9
Gene Alias:
25kDa, 2610029M16Rik, hypothetical protein zgc:77449, LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 9, pre-mRNA-splicing factor SRp30C, serine and arginine rich splicing factor 9, serine/arginine-rich splicing factor 9, Sfrs9, splicing factor, arginine/serine rich 9, splicing factor, arginine/serine-rich 9, SR splicing factor 9, SRP30C, Srsf9, zgc:77449
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
108014, 8683
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
0.65 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q13242, Q9D0B0
Gene Symbols:
SRSF9
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human SFRS9 (NP_0037601)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FUBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FUBP1
Gene Alias: 9530027K12Rik, D3Ertd330e, DNA helicase V, EMBL:AAI07943.1, ECO:0000312, EMBL:AAI07943.1}, far upstream element (FUSE) binding protein 1, far upstream element (FUSE) binding protein 4, far upstream element binding protein 1, far upstream element-binding protein, far upstream element-binding protein 1, far upstream element-binding protein 1 {ECO:0000250, FBP, FBP {ECO:0000250, Fubp, Fubp1, fubp1 {ECO:0000312, Fubp4, FUSE binding protein 1, FUSE-binding protein 1, FUSE-binding protein 1 {ECO:0000250, hDH V, RGD:1591892}, UniProtKB:Q96AE4, ECO:0000312, UniProtKB:Q96AE4}
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51886, 8880
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.39 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q91WJ8, Q96AE4
Gene Symbols: FUBP1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human FUBP1 (NP_0038932)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
FUBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FUBP1
Gene Alias:
9530027K12Rik, D3Ertd330e, DNA helicase V, EMBL:AAI07943.1, ECO:0000312, EMBL:AAI07943.1}, far upstream element (FUSE) binding protein 1, far upstream element (FUSE) binding protein 4, far upstream element binding protein 1, far upstream element-binding protein, far upstream element-binding protein 1, far upstream element-binding protein 1 {ECO:0000250, FBP, FBP {ECO:0000250, Fubp, Fubp1, fubp1 {ECO:0000312, Fubp4, FUSE binding protein 1, FUSE-binding protein 1, FUSE-binding protein 1 {ECO:0000250, hDH V, RGD:1591892}, UniProtKB:Q96AE4, ECO:0000312, UniProtKB:Q96AE4}
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51886, 8880
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.39 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q91WJ8, Q96AE4
Gene Symbols:
FUBP1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human FUBP1 (NP_0038932)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG