PIPA588828
CRTH2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588828-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588828 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CRTH2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGDR2
Gene Alias
CD294, chemoattractant receptor homologous molecule expressed on T helper type 2 cells, chemoattractant receptor-homologous molecule expressed on TH2 cells, CRTH2, DL1R, DP2, G protein-coupled receptor 44, Gpr44, G-protein coupled receptor 44, Grp45, MGC130436, PGD2 receptor, prostaglandin D2 receptor 2, prostaglandin D2 receptor CRTH2, Ptgdr2, putative G-protein coupled receptor 44
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11251, 14764
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.63 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q9Y5Y4, Q9Z2J6
Gene Symbols
PTGDR2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-359 of human PTGDR (NP_0009441)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: GAMRNLYAMH RRLQRHPRSC TRDCAEPRAD GREASPQPLE ELDHLLLLAL MTVLFTMCSL PVIYRAYYGA FKDVKEKNRT SEEAEDLRAL RFLSVISIVD PWIFIIFRSP VFRIFFHKIF IRPLRYRSRC SNSTNMESSL; Positive Samples: NIH/3T3; Cellular Location: Cell membrane, Multi-pass membrane protein CRTH2 (GPR44) is a chemoattractant receptor-homologous molecule expressed on Th2 cells that is an identified receptor for the prostaglandin D2 (PGD2) and prostaglandin D receptor
- CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses
- However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3
- This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo
- CRTH2 is also a novel member of the G protein-coupled leukocyte chemoattractant receptor family, which is selectively expressed in Th2 but not Th1 lineage cells
- CRTH2 has been reported to be expressed in the central nervous system, peripheral tissues, and in blood cells, particularly activated T helper-2 cells
- Two transcripts have been isolated: a 3.5 kb transcript expressed primarily in the thalamus, frontal cortex, pons and hippocampus; and a 3.4 kb transcript expressed in fetal liver, leukocytes and thymus
- CRTH2 is selectively expressed in vivo in an activated state of Th2 cells including allergen-responsive Th2 cells, suggesting its pivotal roles in ongoing Th2-type immune reactions
- At least two different isoforms of CRTH2 are known to exist
- Single nucleotide polymorphisms in the 3' UTR of the CRTH2 gene have been associated with asthma susceptibility.
Compare Similar Items
Show Difference
Antigen: CRTH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTGDR2
Gene Alias: CD294, chemoattractant receptor homologous molecule expressed on T helper type 2 cells, chemoattractant receptor-homologous molecule expressed on TH2 cells, CRTH2, DL1R, DP2, G protein-coupled receptor 44, Gpr44, G-protein coupled receptor 44, Grp45, MGC130436, PGD2 receptor, prostaglandin D2 receptor 2, prostaglandin D2 receptor CRTH2, Ptgdr2, putative G-protein coupled receptor 44
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11251, 14764
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.63 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9Y5Y4, Q9Z2J6
Gene Symbols: PTGDR2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-359 of human PTGDR (NP_0009441)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CRTH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTGDR2
Gene Alias:
CD294, chemoattractant receptor homologous molecule expressed on T helper type 2 cells, chemoattractant receptor-homologous molecule expressed on TH2 cells, CRTH2, DL1R, DP2, G protein-coupled receptor 44, Gpr44, G-protein coupled receptor 44, Grp45, MGC130436, PGD2 receptor, prostaglandin D2 receptor 2, prostaglandin D2 receptor CRTH2, Ptgdr2, putative G-protein coupled receptor 44
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11251, 14764
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.63 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9Y5Y4, Q9Z2J6
Gene Symbols:
PTGDR2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-359 of human PTGDR (NP_0009441)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: LIF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lif
Gene Alias: CDF, cholinergic differentiation factor, cholinergic neuronal differentiation factor, d factor, DIA, differentiation inhibitory activity, differentiation-inducing factor, differentiation-stimulating factor, Emfilermin, hepatocyte-stimulating factor III, HILDA, human interleukin in DA cells, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), LIF, Melanoma-derived LPL inhibitor, MLPLI, myeloid leukaemia inhibitory factor
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16878, 3976
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.68 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P09056, P15018
Gene Symbols: Lif
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 23-202 of human LIF (NP_0023001)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LIF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lif
Gene Alias:
CDF, cholinergic differentiation factor, cholinergic neuronal differentiation factor, d factor, DIA, differentiation inhibitory activity, differentiation-inducing factor, differentiation-stimulating factor, Emfilermin, hepatocyte-stimulating factor III, HILDA, human interleukin in DA cells, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), LIF, Melanoma-derived LPL inhibitor, MLPLI, myeloid leukaemia inhibitory factor
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16878, 3976
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.68 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P09056, P15018
Gene Symbols:
Lif
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 23-202 of human LIF (NP_0023001)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: SYNPO2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SYNPO2
Gene Alias: 1110069I04Rik, 2310068J10Rik, 9530006G20Rik, AI848603, genethonin 2, Genethonin-2, Myo, Myopodin, mypodin, RGD1564779, synaptopodin 2, synaptopodin-2, Synpo2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 118449
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.09 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q91YE8
Gene Symbols: SYNPO2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SYNPO2 (NP_5977342)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SYNPO2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SYNPO2
Gene Alias:
1110069I04Rik, 2310068J10Rik, 9530006G20Rik, AI848603, genethonin 2, Genethonin-2, Myo, Myopodin, mypodin, RGD1564779, synaptopodin 2, synaptopodin-2, Synpo2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
118449
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.09 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q91YE8
Gene Symbols:
SYNPO2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SYNPO2 (NP_5977342)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ADPRM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADPRM
Gene Alias: 2310004I24Rik, ADPRibase-Mn, ADP-ribose/CDP-alcohol diphosphatase, manganese dependent, ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent, ADP-ribose/CDP-alcohol pyrophosphatase, Adprm, C17orf48, CDP-choline phosphohydrolase, liver manganese (II)-dependent ADP-ribose/CDP-alcohol pyrophosphatase, manganese-dependent ADP-ribose/CDP-alcohol diphosphatase, Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like protein, MDS006, NBLA03831, RGD1309906
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 287406, 66358
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.31 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q5M886, Q99KS6
Gene Symbols: ADPRM
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_0646183)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ADPRM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADPRM
Gene Alias:
2310004I24Rik, ADPRibase-Mn, ADP-ribose/CDP-alcohol diphosphatase, manganese dependent, ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent, ADP-ribose/CDP-alcohol pyrophosphatase, Adprm, C17orf48, CDP-choline phosphohydrolase, liver manganese (II)-dependent ADP-ribose/CDP-alcohol pyrophosphatase, manganese-dependent ADP-ribose/CDP-alcohol diphosphatase, Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like protein, MDS006, NBLA03831, RGD1309906
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
287406, 66358
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.31 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q5M886, Q99KS6
Gene Symbols:
ADPRM
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_0646183)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG