PIPA588923

IGF2R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588923-Each-of-1 In Stock ₹ 44,191.74

PIPA588923 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

IGF2R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IGF2R

Gene Alias

300 kDa mannose 6-phosphate receptor, AI661837, cation-independent mannose 6-phosphate receptor, cation-independent mannose 6-phosphate receptor protein, cation-independent mannose-6-phosphate receptor, cation-independent MPR, CD222, CI Man-6-P receptor, CI-M6PR, CIMPR, CI-MPR, Igf2r, IGF-II receptor, IGF-II/CI-MPR, Igfr2, insulin like growth factor 2 receptor, insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, insulin-like growth factor receptor type 2, M6P, M6P/IGF2 receptor, M6P/IGF2R, M6PR, M6P-R, mannose-6-phosphate receptor, cation independent, mannose-6-phosphate/insulin-like growth factor II receptor, MPR 300, MPR1, MPR300, MPRI, similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16004, 25151, 3482

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

0.42 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P11717, Q07113

Gene Symbols

IGF2R

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human Cation-independent M6PR (Cation-independent M6PR (IGF2R)) (NP_0008672)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: YKKERRETVI SKLTTCCRRS SNVSYKYSKV NKEEETDENE TEWLMEEIQL PPPRQGKEGQ ENGHITTKSV KALSSLHGDD QDSEDEVLTI PEVKVHSGRG AGAESSHPVR NAQSNALQER EDDRVGLVRG EKARKGKSSS AQQKTVSSTK LVSFHDDSDE DLLHI; Positive Samples: HeLa; Cellular Location: Lysosome membrane, Single-pass type I membrane protein Lysosomal enzymes containing one or two mannose 6-phosphate (man6P) moieties are moved about in the cell by two distinct but interconnected cycles by means of approximately 300 kDa cation independent mannose 6-phospate receptors (CI-MPR)
  • The biosynthetic cycle refers to the MPR transport of newly synthesized lysosomal enzymes from the trans Golgi network to late endosomes or early lysosomes
  • The endocytic cycle transports extracellular lysosomal enzymes from the plasma membrane via clathrin-coated vesicles to early endosomes
  • The entire pool of MPRs cycles between these cellular compartments every 3 hours
  • The steady state distribution of MPR's is predominantly within late endosomes, fewer in the trans Golgi network and approximately 10 % at cell surface
  • In addition to its man6P binding activity, the MPR contains a separate binding site for the type II insulin-like growth factor and is capable of binding both man6P and IGF-II simultaneously
  • An approximately 240 kDa soluble, truncated form, representing the extracellular domain of the protein, has also been found circulating in serum and is capable of binding both ligands.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA588923

--


Antigen:
IGF2R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF2R

Gene Alias:
300 kDa mannose 6-phosphate receptor, AI661837, cation-independent mannose 6-phosphate receptor, cation-independent mannose 6-phosphate receptor protein, cation-independent mannose-6-phosphate receptor, cation-independent MPR, CD222, CI Man-6-P receptor, CI-M6PR, CIMPR, CI-MPR, Igf2r, IGF-II receptor, IGF-II/CI-MPR, Igfr2, insulin like growth factor 2 receptor, insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, insulin-like growth factor receptor type 2, M6P, M6P/IGF2 receptor, M6P/IGF2R, M6PR, M6P-R, mannose-6-phosphate receptor, cation independent, mannose-6-phosphate/insulin-like growth factor II receptor, MPR 300, MPR1, MPR300, MPRI, similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16004, 25151, 3482

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
0.42 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P11717, Q07113

Gene Symbols:
IGF2R

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human Cation-independent M6PR (Cation-independent M6PR (IGF2R)) (NP_0008672)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588924

--


Antigen:
IGFBP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP7

Gene Alias:
AGM, angiomodulin, FSTL2, IBP7, IBP-7, IGF-binding protein 7, IGFBP, IGFBP rP1, Igfbp7, IGFBP-7, IGFBP-7v, IGFBPRP1, IGFBP-rP1, Insulin like growth factor binding protein, insulin like growth factor binding protein 7, insulin-like growth factor binding protein 7, insulin-like growth factor-binding protein 7, Mac25, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor, PSF, RAMSVPS, TAF, Tumor-derived adhesion factor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
289560, 29817

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q61581

Gene Symbols:
IGFBP7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of human IGFBP7 (NP_0015441)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588927

--


Antigen:
RAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lrpap1

Gene Alias:
39 kDa receptor-associated protein, A2MRAP, A2RAP, AA617339, AI790446, Alpha-2-macroglobulin receptor-associated protein, Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin binding protein-44) (HBP-44), alpha-2-MRAP, AU042172, C77774, gp330-binding 45 kDa protein, HBP44, HBP-44, heparin-binding protein 44, LDL receptor related protein associated protein 1, low density lipoprotein receptor related protein, associated protein 1, low density lipoprotein receptor-related protein associated protein 1, low density lipoprotein receptor-related protein-associated protein 1, low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1), Lrpap1, MRAP, MYP23, RAP

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116565, 16976, 4043

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.83 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P30533, P55302, Q99068

Gene Symbols:
Lrpap1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-357 of human LRPAP1 (NP_0023281)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588929

--


Antigen:
MTNR1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTNR1A

Gene Alias:
mel1a melatonin receptor, mel1a receptor, Mel-1A-R, melatonin receptor 1A, melatonin receptor type 1A, MelR, MR, MT1, Mtnr1a

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114211, 17773, 4543

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P48039, P49218, Q61184

Gene Symbols:
MTNR1A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 281-350 of human MTNR1A (NP_0059491)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG