PIPA589000

GOLPH3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA589000-Each-of-1 In Stock ₹ 44,705.10

PIPA589000 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GOLPH3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Golph3

Gene Alias

4733401N08Rik, 5730410D03Rik, AW413496, coat protein GPP34, coat-protein, Gmx33, golgi peripheral membrane protein 1, 34 kDa, Golgi phosphoprotein 3, golgi phosphoprotein 3 (coat-protein), golgi protein, golgi-associated protein, GOLPH3, GOPP1, GPP34, MIDAS, Mitochondrial DNA absence factor, trans-Golgi protein GMx33, Vps74

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64083, 66629, 78961

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.87 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q9CRA5, Q9ERE4, Q9H4A6

Gene Symbols

Golph3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human GOLPH3 (NP_0714131)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MTSLTQRSSG LVQRRTEASR NAADKERAAG GGAGSSEDDA QSRRDEQDDD DKGDSKETRL TLMEEVLLLG LKDREGYTSF WNDCISSGLR GCMLIELALR GRLQLEACGM RRKSLLTRKV ICKSDAPTGD VLLDEALKHV KETQPPETVQ NWIELLSGET WNPLKLHYQL RNVRERLAKN LVEKGVLTTE KQNFLLFDMT THPLTNNNIK QRLIKKVQEA VLDKWVNDPH RMDRRLLALI YLAHASDVLE NAFAPLLDEQ YDLATKRVRQ LLDLDPEVEC LKANTNEVLW AVVAAFTK; Positive Samples: 22Rv1, LO2, HeLa, Mouse testis, Rat lung; Cellular Location: Cell membrane, Cytoplasmic side, Endosome, Golgi apparatus, Golgi stack membrane, Mitochondrion intermembrane space, Peripheral membrane protein, trans-Golgi network membrane GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin
  • GOLPH3 has since been implicated in the target of rapamycin (TOR) signaling pathway
  • Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro
  • Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF
  • Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signaling through TOR-associated complexes
  • These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.

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Show Difference

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Thermo Scientific

PIPA589000

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Antigen:
GOLPH3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Golph3

Gene Alias:
4733401N08Rik, 5730410D03Rik, AW413496, coat protein GPP34, coat-protein, Gmx33, golgi peripheral membrane protein 1, 34 kDa, Golgi phosphoprotein 3, golgi phosphoprotein 3 (coat-protein), golgi protein, golgi-associated protein, GOLPH3, GOPP1, GPP34, MIDAS, Mitochondrial DNA absence factor, trans-Golgi protein GMx33, Vps74

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64083, 66629, 78961

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.87 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q9CRA5, Q9ERE4, Q9H4A6

Gene Symbols:
Golph3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human GOLPH3 (NP_0714131)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA589001

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Antigen:
TINAGL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TINAGL1

Gene Alias:
1110021J17Rik, Adrenocortical zonation factor 1, androgen-regulated gene 1, androgen-regulated gene 1 protein, Arg1, AZ1, AZ-1, Gis5, glucocorticoid-inducible protein 5, LCN7, LIECG3, lipocalin 7, OLRG2, OLRG-2, Oxidized LDL-responsive gene 2 protein, oxidized-LDL responsive gene 2, P3ECSL, PP6614, PSEC0088, TARP, TIN Ag-related protein, Tinagl, TINAGL1, TINAG-like 1, TINAGRP, TIN-Ag-RP, tubulointerstitial nephritis antigen like 1, tubulointerstitial nephritis antigen-like, tubulointerstitial nephritis antigen-like 1, tubulointerstitial nephritis antigen-related protein, UNQ204/PRO230

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64129, 94174, 94242

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.79 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q99JR5, Q9EQT5, Q9GZM7

Gene Symbols:
TINAGL1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 258-467 of human TINAGL1 (NP_0714471)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA589005

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Antigen:
DYNC2H1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DYNC2H1

Gene Alias:
4432416O06Rik, AI448217, ATD3, b2b414Clo, Cytoplasmic dynein 2 heavy chain, Cytoplasmic dynein 2 heavy chain 1, cytoplasmic dynein heavy chain 2, D030010H02Rik, D330044F14Rik, DHC1b, DHC2, Dlp4, Dnch2, Dnchc2, DYH1B, Dync2h1, dynein cytoplasmic 2 heavy chain 1, dynein cytoplasmic heavy chain 2, Dynein heavy chain 11, dynein heavy chain 2, dynein heavy chain isotype 1B, dynein heavy chain, isotype 1B, dynein, cytoplasmic 2, heavy chain 1, dynein, cytoplasmic, heavy chain 2, dynein, cytoplasmic, heavy polypeptide 2, dynein-like protein 4, hDHC11, KIAA1997, mDHC11, mKIAA1997, SRPS2B, SRTD3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
65209

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.44 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q9JJ79

Gene Symbols:
DYNC2H1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DYNC2H1 (NP_0010739321)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA589007

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Antigen:
CDK5RAP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDK5RAP3

Gene Alias:
1810007E24Rik, BC002318, C53, C81486, CDK5 activator-binding protein C53, CDK5 activator-binding protein C53, CDK5 regulatory subunit associated protein 3, CDK5 regulatory subunit associated protein IC53-2, CDK5 regulatory subunit-associated protein 3, Cdk5rap3, HSF-27, IC53, IC53-2, ischemic heart CDK5 activator-binding protein C53, LXXLL/leucine-zipper-containing ARFbinding protein, LXXLL/leucine-zipper-containing ARF-binding protein, LZAP, MST016, MSTP016, OK/SW-cl.114, PP1553, Protein HSF-27

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80279

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q96JB5

Gene Symbols:
CDK5RAP3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDK5RAP3 (NP_7882761)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG