PIPA589122

YTHDF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA589122-Each-of-1 In Stock ₹ 44,191.74

PIPA589122 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

YTHDF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

YTHDF1

Gene Alias

2210410K23Rik, 8030473O16, C20orf21, DACA-1, DACA-1 homolog, Dermatomyositis associated with cancer putative autoantigen 1, dermatomyositis associated with cancer putative autoantigen 1 homolog, fb49c02, wu:fb49c02, wu:fi19h06, wu:fj87f09, wu:fp06c11, YTH domain family 1, YTH domain family protein 1, YTH domain family, member 1, YTH domain-containing family protein 1, YTH N(6)-methyladenosine RNA binding protein 1, YTH N6-methyladenosine RNA binding protein 1, Ythdf1, zgc:55657

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

228994, 296467, 54915

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

0.92 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P59326, Q9BYJ9

Gene Symbols

YTHDF1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human YTHDF1 (NP_0602682)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: HepG2, Jurkat; Cellular Location: Cytoplasm Immunogen sequence: MSATSVDTQR TKGQDNKVQN GSLHQKDTVH DNDFEPYLTG QSNQSNSYPS MSDPYLSSYY PPSIGFPYSL NEAPWSTAGD PPIPYLTTYG QLSNGDHHFM HDAVFGQPGG LGNNIYQHRF NFFPENPAFS AWGTSGSQGQ QTQSSAYGSS YTYPPSSLGG TVVDGQPGFH SDTLSKAPGM NSLEQGMVGL KIGDVSSSAV Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451)
  • M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625)
  • Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440)
  • Required to facilitate learning and memory formation in the hippocampus by enhancing protein synthesis upon neuronal stimulation: in response to neuronal stimulation, binds to m6A-containing neuronal mRNAs, promoting their translation, thereby contributing to learning and memory
  • Acts as a regulator of axon guidance by binding to m6A-containing ROBO3 transcripts, thereby promoting their translation
  • Acts as a negative regulator of antigen cross-presentation in myeloid dendritic cells
  • Acts by binding and promoting translation of m6A-containing transcripts encoding proteins involved in lysosomal degradation and phagosome maturation, leading to increased antigen degradation in myeloid dendritic cells
  • In the context of tumorigenesis, negative regulation of antigen cross-presentation limits the anti-tumor response by reducing efficiency of tumor-antigen cross-presentation
  • [UniProt]

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Img

Thermo Scientific

PIPA589122

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Antigen:
YTHDF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YTHDF1

Gene Alias:
2210410K23Rik, 8030473O16, C20orf21, DACA-1, DACA-1 homolog, Dermatomyositis associated with cancer putative autoantigen 1, dermatomyositis associated with cancer putative autoantigen 1 homolog, fb49c02, wu:fb49c02, wu:fi19h06, wu:fj87f09, wu:fp06c11, YTH domain family 1, YTH domain family protein 1, YTH domain family, member 1, YTH domain-containing family protein 1, YTH N(6)-methyladenosine RNA binding protein 1, YTH N6-methyladenosine RNA binding protein 1, Ythdf1, zgc:55657

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228994, 296467, 54915

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
0.92 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P59326, Q9BYJ9

Gene Symbols:
YTHDF1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human YTHDF1 (NP_0602682)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589123

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Antigen:
Podoplanin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
29kDa cytosolic podoplanin intracellular domain, Aggrus, CTA-520D8.1, E11, E11 antigen epitope, epithelial cell surface transmembrane protein antigen, glycoprotein 36, Glycoprotein 38, glycoprotein, 36-KD, GP36, Gp38, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), Ots8, OTS-8, OTTHUMP00000009640, OTTHUMP00000044504, PA2.26, PA2.26 antigen, PDPN, PICD, Podoplanin, PSEC0003, PSEC0025, pulmonary type I alveolar epithelial cell transmembrane differentiation marker, RANDAM-2, RP23-348F1.2, RTI140, RTI40, T1a, T1A2, T1A-2, T1alpha, T1-alpha, TI1A, Transmembrane glycoprotein E11, type I cell 40 kDa protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10630, 14726, 54320

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.01 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
Q62011, Q64294, Q86YL7

Gene Symbols:
PDPN

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-131 of human Podoplanin (NP_0064653)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589125

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Antigen:
TSPAN8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tspan8

Gene Alias:
C76990, CO-029, CO-29, D6.1A, E330007O21Rik, tetraspanin 8, Tetraspanin8, tetraspanin-8, Tm4sf3, transmembrane 4 superfamily member 3, TSPAN8, Tspan-8, Tumor-associated antigen CO-029

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171048, 216350

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.98 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8R3G9

Gene Symbols:
Tspan8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-200 of human TSPAN8 (NP_0046071)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589126

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Antigen:
YOD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YOD1

Gene Alias:
9930028C20Rik, DUBA8, DUBA-8, fe01a10, HIN7, HIN-7, HIV-1-induced protease 7, HIV-induced protein-7-like protease, hsHIN7, hypothetical protein LOC550411, OTU domain containing 2, OTU domain-containing protein 2, OTUD2, PRO0907, Ubiquitin thioesterase OTU1, wu:fe01a10, Yod1, YOD1 deubiquitinase, YOD1 OTU deubiquinating enzyme 1 homolog, YOD1 OTU deubiquinating enzyme 1 homolog ( yeast), YOD1 OTU deubiquitinating enzyme 1 homologue, YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae), zgc:112182

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
226418, 55432

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.46 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
Q5VVQ6, Q8CB27

Gene Symbols:
YOD1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human YOD1 (NP_0610363)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG