PIPA589302

USP7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA589302-Each-of-1 In Stock ₹ 44,705.10

PIPA589302 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

USP7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

USP7

Gene Alias

2210010O09Rik, AA409944, AA617399, AU019296, AW548146, C80752, deubiquitinating enzyme 7, Hausp, Herpes virus-associated ubiquitin-specific protease, herpes-virus-associated ubiquitin-specific protease, herpesvirus-associated ubiquitin-specific protease, mHAUSP, protease, rHAUSP, TEF1, Ubiquitin carboxyl-terminal hydrolase 7, ubiquitin specific peptidase 7, ubiquitin specific peptidase 7 (herpes virus-associated), ubiquitin specific protease 7, ubiquitin specific protease 7 (herpes virus-associated), ubiquitin thioesterase 7, ubiquitin thiolesterase 7, ubiquitin-specific-processing protease 7, UBP, USP7

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

252870, 360471, 7874

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.53 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q4VSI4, Q6A4J8, Q93009

Gene Symbols

USP7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7/HAUSP (NP_0034612)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: DSKKHTGYVG LKNQGATCYM NSLLQTLFFT NQLRKAVYMM PTEGDDSSKS VPLALQRVFY ELQHSDKPVG TKKLTKSFGW ETLDSFMQHD VQELCRVLLD NVENKMKGTC VEGTIPKLFR GKMVSYIQCK EVDYRSDRRE DYYDIQLSIK GKKNIFESFV DYVAVEQLDG DNKYDAGEHG LQEAEKGVKF LTLPPVLHLQ LMRFMYDPQT DQNIKINDRF EFPEQLPLDE FLQKTDPKDP ANYILHAVLV HSGDNHGGHY VVYLNPKGDG KWCKFDDDVV SRCTKEEAIE HNYGGHDDDL SVRHCTNAYM LVYIRESKLS EVLQAVTDHD IPQQLVERLQ EEKRIEAQKR KERQEAHLYM QVQIVAEDQF CGHQGNDMYD EEKVKYTVFK VLKNSSLAEF VQSLSQTMGF PQDQIRLWPM QARSNGTKRP AMLDNEADGN KTMIELSDNE NPWTIFLETV DPELAASGAT LPKFDKDHDV MLFLKMYDPK TRSLNYCGHI YTPISCKIRD LLPVMCDRAG FIQDTSLILY EEVKPNLTER IQDYDVSLDK ALDELMDGDI IVFQKDDPEN DNSELPTAKE YFRDLYHRVD VIFCDKTIPN DPGFVVTLSN RMNYFQVAKT VAQRLNTDPM LLQFFKSQGY RDGPGNPLRH NYEGTLRDLL QFFKPRQPKK LYYQQLKMKI TDFENRRSFK CIWLNSQFRE EEITLYPDKH GCVRDLLEEC KKAVELGEKA SGKLRLLEIV SYKIIGVHQE DELLECLSPA TSRTFRIEEI PLDQVDIDKE NEMLVTVAHF HKEVFGTFGI PFLLRIHQGE HFREVMKRIQ SLLDIQEKEF EKFKFAIVMM GRHQYINEDE YEVNLKDFEP QPGNMSHPRP WLGLDHFNKA PKRSRYTYLE KAIKIHN; Positive Samples: HepG2, Rat testis; Cellular Location: Cytoplasm, Nucleus, PML body USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
  • Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
  • HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
  • Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
  • Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
  • Another important role of HAUSP function involves the oncogenic stabilization of p53
  • Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
  • An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.

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Thermo Scientific

PIPA589302

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Antigen:
USP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP7

Gene Alias:
2210010O09Rik, AA409944, AA617399, AU019296, AW548146, C80752, deubiquitinating enzyme 7, Hausp, Herpes virus-associated ubiquitin-specific protease, herpes-virus-associated ubiquitin-specific protease, herpesvirus-associated ubiquitin-specific protease, mHAUSP, protease, rHAUSP, TEF1, Ubiquitin carboxyl-terminal hydrolase 7, ubiquitin specific peptidase 7, ubiquitin specific peptidase 7 (herpes virus-associated), ubiquitin specific protease 7, ubiquitin specific protease 7 (herpes virus-associated), ubiquitin thioesterase 7, ubiquitin thiolesterase 7, ubiquitin-specific-processing protease 7, UBP, USP7

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
252870, 360471, 7874

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q4VSI4, Q6A4J8, Q93009

Gene Symbols:
USP7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7/HAUSP (NP_0034612)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589304

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Antigen:
TCAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tcap

Gene Alias:
19 kDa sarcomeric protein, AI503981, AJ223855, CMD1N, CMH25, LGMD2G, limb girdle muscular dystrophy 2G (autosomal recessive), Tcap, T-cap, TELE, telethonin, teneurin C-terminal associated peptide, titin cap protein, titin-cap, titin-cap (telethonin)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21393, 688173, 8557

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.39 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O15273, O70548

Gene Symbols:
Tcap

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_0036641)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589306

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Antigen:
FIBP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FIBP

Gene Alias:
2010004G08Rik, 2010005N21Rik, 3010027N18Rik, Acidic fibroblast growth factor intracellular-binding protein, aFGF intracellular binding protein, aFGF intracellular-binding protein, FGF intracellular binding protein, FGF1 intracellular binding protein, FGF-1 intracellular-binding protein, FGFIBP, Fibp, FIBP-1, fibroblast growth factor (acidic) intracellular binding protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58249, 9158

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.62 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O43427, Q9JI19

Gene Symbols:
FIBP

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human FIBP (NP_0042052)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA589311

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Antigen:
RAD54L2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD54L2

Gene Alias:
Androgen receptor-interacting protein 4, AR interacting protein 4, ARIP4, Helicase ARIP4, HSPC325, KIAA0809, Rad54 like 2, RAD54L2, RAD54-like 2 (S. cerevisiae), RAD54-like protein 2, RGD1561889, SRISNF2L

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23132

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9Y4B4

Gene Symbols:
RAD54L2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1178-1467 of human RAD54L2 (NP_0559212)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG