PIPA589316

DNMT3L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA589316-Each-of-1 In Stock ₹ 44,705.10

PIPA589316 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DNMT3L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNMT3L

Gene Alias

cytosine-5-methyltransferase 3-like protein, D6Ertd14e, DNA (cytosine-5-)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3-like, DNA methyltransferase 3 like, Dnmt 3L, DNMT3L, ecat7, human cytosine-5-methyltransferase 3-like protein, MGC1090

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29947, 54427

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.06 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q9CWR8, Q9UJW3

Gene Symbols

DNMT3L

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 151-386 of human DNMT3L (NP_7870631)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: SGLLQRRRKW RSQLKAFYDR ESENPLEMFE TVPVWRRQPV RVLSLFEDIK KELTSLGFLE SGSDPGQLKH VVDVTDTVRK DVEEWGPFDL VYGATPPLGH TCDRPPSWYL FQFHRLLQYA RPKPGSPRPF FWMFVDNLVL NKEDLDVASR FLEMEPVTIP DVHGGSLQNA VRVWSNIPAI RSRHWALVSE EELSLLAQNK QSSKLAAKWP TKLVKNCFLP LREYFKYFST ELTSSL; Positive Samples: HeLa, Jurkat, 293T, Mouse testis, Mouse thymus, Mouse ovary, Rat testis; Cellular Location: Nucleus Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and development
  • Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2, and DNMT3
  • DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication
  • DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues
  • DNMT3A and DNMT3B function as de novo methyltransferases that methylate previously unmethylated regions of DNA
  • DNMT2 is expressed at low levels in adult somatic tissues and its inactivation affects neither de novo nor maintenance DNA methylation
  • DNMT3L is a catalytically inactive regulatory factor for the DNMT3A and DNMT3B de novo methyltransferases that is expressed at low levels in embryonic stem cells, testis, ovaries, and thymus
  • These de novo methyltransferases consist of a heterotetrameric complex containing two molecules of DNMT3L, and either two molecules of DNMT3A or DNMT3B
  • DNMT3L contains an amino-terminal ATRX-DNMT3-DNMT3L (ADD) domain and a carboxy-terminal methyltransferase-like domain.

Compare Similar Items

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Img

Thermo Scientific

PIPA589316

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Antigen:
DNMT3L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNMT3L

Gene Alias:
cytosine-5-methyltransferase 3-like protein, D6Ertd14e, DNA (cytosine-5-)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3-like, DNA methyltransferase 3 like, Dnmt 3L, DNMT3L, ecat7, human cytosine-5-methyltransferase 3-like protein, MGC1090

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29947, 54427

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9CWR8, Q9UJW3

Gene Symbols:
DNMT3L

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 151-386 of human DNMT3L (NP_7870631)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589319

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Antigen:
GBL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MLST8

Gene Alias:
0610033N12Rik, AA409454, AI505104, AI851821, G beta-like protein, G protein beta subunit-like, Gable, GbetaL, GBL, GBL protein, Lst8, Mammalian lethal with SEC13 protein 8, mLST8, mLST8 / mLST8, MTOR associated protein, LST8 homolog, MTOR associated protein, LST8 homolog (S. cerevisiae), POP3, protein GbetaL, Target of rapamycin complex subunit LST8, TORC subunit gable, TORC subunit LST8, TORC subunit WAT1, transducin (beta)-like 4, WAT1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56716, 64223, 64226

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.83 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q9BVC4, Q9DCJ1, Q9Z2K5

Gene Symbols:
MLST8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human MLST8 (NP_0011861031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589321

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Antigen:
MFN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MFN2

Gene Alias:
CMT2A, CMT2A2, CPRP 1, CPRP1, D630023P19Rik, Fzo, HMSN6A, HSG, HSG protein, hyperplasia suppressor, hypertension related protein 1, hypertension-related protein, hypertension-related protein 1, Kiaa0214, LOW QUALITY PROTEIN: mitofusin-2, Marf, MFN 2, MFN2, mg:cb01g09, Mitochondrial assembly regulatory factor, mitochondrial transmembrane GTPase FZO1A, mitofusin 2, Mitofusin2, mitofusin-2, si:dkeyp-104h9.2, Transmembrane GTPase MFN2, wu:fb79a11

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170731, 64476, 9927

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O95140, Q80U63, Q8R500

Gene Symbols:
MFN2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of mouse Mitofusin 2 (NP_5734642)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589322

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Antigen:
Tyrosinase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TYR

Gene Alias:
albino, albino locus protein, ATN, C, CMM8, LB24-AB, monophenol monooxygenase, Oca1, OCA1A, OCAIA, oculocutaneous albinism IA, SHEP3, SK29-AB, skc35, Tumor rejection antigen AB, TYR, Tyrosinase, tyrosinase (oculocutaneous albinism IA), tyrosinase precursor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
308800, 7299

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P14679

Gene Symbols:
TYR

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-340 of human Tyrosinase (NP_0003631)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG