PIPA589420
HSF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589420-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA589420 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
HSF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hsf1
Gene Alias
AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15499, 3297, 79245
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.83 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P38532, Q00613
Gene Symbols
Hsf1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 350-529 of human HSF1 (NP_0055171)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: DARGHTDTEG RPPSPPPTST PEKCLSVACL DKNELSDHLD AMDSNLDNLQ TMLSSHGFSV DTSALLDLFS PSVTVPDMSL PDLDSSLASI QELLSPQEPP RPPEAENSSP DSGKQLVHYT AQPLFLLDPG SVDTGSNDLP VLFELGEGSY FSEGDGFAED PTISLLTGSE PPKAKDPTVS; Positive Samples: HeLa, K-562, HepG2, MCF7; Cellular Location: Cytoplasm, Nucleus All organisms respond to elevated temperatures and a variety of environmental stresses by rapid synthesis of heat shock RNAs and proteins
- The regulation of heat shock gene transcription is mediated by the transcriptional activator, heat shock factor (HSF), which binds to heat shock response elements (HSEs)
- These HSEs are found as three repeats of a 5-nucleotide {nGAAn} module, arranged in alternating orientation and present upstream of all heat shock genes
- The HSEs are highly conserved among species yet HSF purified from yeast, Drosophila and human have different molecular weights and the proteins do not show significant immunological cross reaction
- Two HSFs have been identified in human cells, HSF1 and HSF2, which bind to the same HSEs and have 38% sequence identity
- These factors are activated by distinct stimuli, HSF1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF2 is activated during hemin-mediated differentiation of human erythroleukemia cells
- HSF1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity
- Through an unknown signal generated during stress, HSF1 becomes activated to a nuclear localized, trimeric state which binds to DNA
- The phosphorylation of HSF1 is necessary for maximal transcription of heat shock genes.
Compare Similar Items
Show Difference
Antigen: HSF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hsf1
Gene Alias: AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15499, 3297, 79245
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.83 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P38532, Q00613
Gene Symbols: Hsf1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-529 of human HSF1 (NP_0055171)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HSF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hsf1
Gene Alias:
AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15499, 3297, 79245
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.83 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P38532, Q00613
Gene Symbols:
Hsf1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-529 of human HSF1 (NP_0055171)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: EHD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EHD4
Gene Alias: 2210022F10Rik, AI197390, AI846352, AV006278, EH domain containing 4, EH domain containing protein MPAST2, EH domain-containing protein 4, EHD4, EH-domain containing 4, FKSG7, HCA10, HCA11, Hepatocellular carcinoma-associated protein 10/11, hepatocellular carcinoma-associated protein HCA11, mPAST2, ortholog of rat pincher, PAST homolog 2, PAST homolog 4, Past2, PAST4, pincher, pinocytic chaperone
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 30844, 98878
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.46 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9EQP2, Q9H223
Gene Symbols: EHD4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_6446701)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
EHD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EHD4
Gene Alias:
2210022F10Rik, AI197390, AI846352, AV006278, EH domain containing 4, EH domain containing protein MPAST2, EH domain-containing protein 4, EHD4, EH-domain containing 4, FKSG7, HCA10, HCA11, Hepatocellular carcinoma-associated protein 10/11, hepatocellular carcinoma-associated protein HCA11, mPAST2, ortholog of rat pincher, PAST homolog 2, PAST homolog 4, Past2, PAST4, pincher, pinocytic chaperone
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
30844, 98878
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.46 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9EQP2, Q9H223
Gene Symbols:
EHD4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_6446701)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: P4HA3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4ha3
Gene Alias: 4-PH alpha-3, collagen prolyl 4-hydroxylase alpha 3, collagen prolyl 4-hydroxylase alpha III subunit, collagen prolyl 4-hydroxylase alpha(III), C-P4H alpha III, D930031A02Rik, P4ha3, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3, prolyl 4-hydroxylase subunit alpha 3, prolyl 4-hydroxylase subunit alpha-3, prolyl 4-hydroxylase, alpha polypeptide III, UNQ711/PRO1374
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 283208, 320452, 361612
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.44 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q6W3E9, Q6W3F0, Q7Z4N8
Gene Symbols: P4ha3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human P4HA3 (NP_8789071)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
P4HA3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4ha3
Gene Alias:
4-PH alpha-3, collagen prolyl 4-hydroxylase alpha 3, collagen prolyl 4-hydroxylase alpha III subunit, collagen prolyl 4-hydroxylase alpha(III), C-P4H alpha III, D930031A02Rik, P4ha3, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3, prolyl 4-hydroxylase subunit alpha 3, prolyl 4-hydroxylase subunit alpha-3, prolyl 4-hydroxylase, alpha polypeptide III, UNQ711/PRO1374
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
283208, 320452, 361612
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.44 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q6W3E9, Q6W3F0, Q7Z4N8
Gene Symbols:
P4ha3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human P4HA3 (NP_8789071)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CYP1B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cyp1b1
Gene Alias: aryl hydrocarbon hydroxylase, benz[a]anthracene inducible, CP1B, CYP1B, CYP1B1, Cyp1-b1, CYPIB1, cytochrome P450 1B, cytochrome P450 1B1, cytochrome P450 family 1 subfamily B member 1, cytochrome P450, 1b1, benz[a]anthracene inducible, cytochrome P450, family 1, subfamily B, polypeptide 1, cytochrome P450, subfamily 1B, polypeptide 1, cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile), cytochrome P4501B, cytochrome P450CMEF, Cytochrome P450EF, cytochrome P450RAP, flavoprotein-linked monooxygenase, GLC3A, Hydroperoxy icosatetraenoate dehydratase, microsomal monooxygenase, P4501B1, P450RAP, xenobiotic monooxygenase, zgc:136223
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13078, 1545, 25426
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.46 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q16678, Q64429, Q64678
Gene Symbols: Cyp1b1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CYP1B1 (NP_0000952)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CYP1B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cyp1b1
Gene Alias:
aryl hydrocarbon hydroxylase, benz[a]anthracene inducible, CP1B, CYP1B, CYP1B1, Cyp1-b1, CYPIB1, cytochrome P450 1B, cytochrome P450 1B1, cytochrome P450 family 1 subfamily B member 1, cytochrome P450, 1b1, benz[a]anthracene inducible, cytochrome P450, family 1, subfamily B, polypeptide 1, cytochrome P450, subfamily 1B, polypeptide 1, cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile), cytochrome P4501B, cytochrome P450CMEF, Cytochrome P450EF, cytochrome P450RAP, flavoprotein-linked monooxygenase, GLC3A, Hydroperoxy icosatetraenoate dehydratase, microsomal monooxygenase, P4501B1, P450RAP, xenobiotic monooxygenase, zgc:136223
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13078, 1545, 25426
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.46 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q16678, Q64429, Q64678
Gene Symbols:
Cyp1b1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CYP1B1 (NP_0000952)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG