PIPA589480

Bora Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA589480-Each-of-1 In Stock ₹ 44,705.10

PIPA589480 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Bora

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BORA

Gene Alias

6720463M24Rik, AI317232, aurora borealis, BORA, bora, aurora kinase A activator, C13orf34, HsBora, Protein aurora borealis, RGD1309522, RP11-342J4.2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79866

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.97 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q6PGQ7

Gene Symbols

BORA

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 260-559 of human BORA (NP_079084.4).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: KYSLGSITSP SPISSPTFSP IEFQIGETPL SEQRKFTVHS PDASSGTNSN GITNPCIRSP YIDGCSPIKN WSPMRLQMYS GGTQYRTSVI QIPFTLETQG EDEEDKENIP STDVSSPAMD AAGIHLRQFS NEASTHGTHL VVTAMSVTQN QSSASEKELA LLQDVEREKD NNTVDMVDPI EIADETTWIK EPVDNGSLPM TDFVSGIAFS IENSHMCMSP LAESSVIPCE SSNIQMDSGY NTQNCGSNIM DTVGAESYCK ESDAQTCEVE SKSQAFNMKQ DHTTQRCWMK TASPFQCSSP; Positive Samples: HT-29, HeLa Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation during mitosis
  • Bora is localized to the nucleus until mitosis is initiated, then translocates to the cytoplasm in a Cdc2 dependent manner
  • Activation of Cdc2 initiates the release of Bora into the cytoplasm where it can bind and activate ARK-1
  • PLK1 (polo-like kinase-1) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation by ARK-1
  • Bora and ARK-1 cooperatively activate PLK1 and control mitotic entry
  • Bora mutants result in multipolar spindles in mitosis identical to those observed when ARK-1 function is blocked
  • Thus, the ARK1-Bora-PLK1 regulatory circuit in mammalian cells elucidates a key mechanism in cell cycle regulation
  • At least three isoforms of Bora are known to exist.

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Img

Thermo Scientific

PIPA589480

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Antigen:
Bora

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BORA

Gene Alias:
6720463M24Rik, AI317232, aurora borealis, BORA, bora, aurora kinase A activator, C13orf34, HsBora, Protein aurora borealis, RGD1309522, RP11-342J4.2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79866

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q6PGQ7

Gene Symbols:
BORA

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-559 of human BORA (NP_079084.4).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589481

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Antigen:
ZNF333

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF333

Gene Alias:
KIAA1806, Zinc finger protein 333, ZNF333

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84449

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q96JL9

Gene Symbols:
ZNF333

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human ZNF333 (NP_0012878411)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589482

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Antigen:
CPT1C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CPT1C

Gene Alias:
6530437J22Rik, 9630004I06Rik, Carnitine O-palmitoyltransferase 1, brain isoform, carnitine O-palmitoyltransferase I, brain isoform, carnitine palmitoyltransferase 1, brain, carnitine palmitoyltransferase 1c, carnitine palmitoyltransferase I related C, CATL1, CPT IC, CPT I-C, CPT1-B, Cpt1c, CPT1P, CPTI-B, CPTIC, FLJ23809, SPG73

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126129, 308579, 78070

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
7.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
F1LN46, Q8BGD5, Q8TCG5

Gene Symbols:
CPT1C

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-400 of human CPT1C (NP_0011295241)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589483

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Antigen:
CDHR5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDHR5

Gene Alias:
1810074H01Rik, AI481143, Cadherin, cadherin related family member 5, cadherin-related family member 5, CDHR5, differentiation-associated catenin regulator, GP100, MLPCDH, MUCDHL, mucin and cadherin like, mucin and cadherin-like protein, Mucin-like protocadherin, Mupcdh, MU-PCDH, mu-protocadherin, UNQ2781/PRO7168

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171554, 72040

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.9 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8VHF2, Q9JIK1

Gene Symbols:
CDHR5

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-220 of human CDHR5 (NP_1125542)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG