PIPA589523
HIC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589523-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA589523 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
HIC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hic1
Gene Alias
AA408311, HIC1, hic-1, hypermethylated in cancer 1, hypermethylated in cancer 1 protein, ZBTB29, Zinc finger and BTB domain-containing protein 29, ZNF901
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15248
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.6 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q9R1Y5
Gene Symbols
Hic1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-430 of human HIC1 (NP_0010916721)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AATPVIQACY PSPVGPPPPP AAEPPSGPEA AVNTHCAELY ASGPGPAAAL CASERRCSPL CGLDLSKKSP PGSAAPERPL AERELPPRPD SPPSAGPAAY KEPPLALPSL PPLPFQKLEE AAPPSDPFRG GSGSPGPEPP GRPDGPSLLY RWMKHEPGLG SYGDELGRER GSPSERCEER GGDAAVSPGG PPLGLAPPPR YPGSLDGPGA GGDGDDYKSS SEETGSSEDP SPPGGHLEGY PCPHLAYGEP E; Positive Samples: Mouse liver; Cellular Location: Nucleus Hypermethylated in cancer (HIC-1) was originally identified as a target of p53-induced gene expression
- HIC-1 is deleted in the genetic disorder Miller-Dieker syndrome (MDS), and the expression of HIC-1 is also frequently suppressed in leukemia and various cancers due to the hypermethylation of specific DNA regions and the resulting transcriptional silencing
- These and other studies indicate that HIC-1 acts as a putative tumor suppressor protein that mediates transcriptional repression
- HIC-1 is ubiquitously expressed in adult tissues and its structure is defined by five zinc fingers and an N-terminal broad complex POZ (or BTB) domain
- In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription
- When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated
- Conversely, HIC-1 does not interact with components of the HDAC complex, suggesting that HIC-1-induced transcriptional repression is unassociated with the POZ/BTB domain.
Compare Similar Items
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Antigen: HIC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hic1
Gene Alias: AA408311, HIC1, hic-1, hypermethylated in cancer 1, hypermethylated in cancer 1 protein, ZBTB29, Zinc finger and BTB domain-containing protein 29, ZNF901
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15248
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.6 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9R1Y5
Gene Symbols: Hic1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-430 of human HIC1 (NP_0010916721)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HIC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hic1
Gene Alias:
AA408311, HIC1, hic-1, hypermethylated in cancer 1, hypermethylated in cancer 1 protein, ZBTB29, Zinc finger and BTB domain-containing protein 29, ZNF901
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15248
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.6 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9R1Y5
Gene Symbols:
Hic1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-430 of human HIC1 (NP_0010916721)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: VAMP8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VAMP8
Gene Alias: AU041171, Edb, endobrevin, hypothetical protein LOC507309, vamp, VAMP8, VAMP-8, vesicle associated membrane protein 8, vesicle-associated membrane protein 8, vesicle-associated membrane protein 8 (endobrevin), wu:fa18d07, zgc:56588
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22320, 83730, 8673
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.56 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O70404, Q9BV40, Q9WUF4
Gene Symbols: VAMP8
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human VAMP8 (NP_0037522)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VAMP8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VAMP8
Gene Alias:
AU041171, Edb, endobrevin, hypothetical protein LOC507309, vamp, VAMP8, VAMP-8, vesicle associated membrane protein 8, vesicle-associated membrane protein 8, vesicle-associated membrane protein 8 (endobrevin), wu:fa18d07, zgc:56588
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22320, 83730, 8673
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.56 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O70404, Q9BV40, Q9WUF4
Gene Symbols:
VAMP8
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human VAMP8 (NP_0037522)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LIMS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LIMS1
Gene Alias: 2310016J22Rik, 4921524A02Rik, AI507642, AU021743, AW551584, C430041B13Rik, LIM and senescent cell antigen-like domains 1, LIM and senescent cell antigen-like-containing domain protein 1, LIM zinc finger domain containing 1, LIMS1, Lims1l, LIM-type zinc finger domains 1, Particularly interesting new Cys-His protein 1, PINCH, PINCH1, PINCH-1, renal carcinoma antigen NY-REN-48, RGD1560732, senescent cell antigen
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110829, 3987
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.51 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P48059, Q99JW4
Gene Symbols: LIMS1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human LIMS1 (NP_0011804171)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LIMS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LIMS1
Gene Alias:
2310016J22Rik, 4921524A02Rik, AI507642, AU021743, AW551584, C430041B13Rik, LIM and senescent cell antigen-like domains 1, LIM and senescent cell antigen-like-containing domain protein 1, LIM zinc finger domain containing 1, LIMS1, Lims1l, LIM-type zinc finger domains 1, Particularly interesting new Cys-His protein 1, PINCH, PINCH1, PINCH-1, renal carcinoma antigen NY-REN-48, RGD1560732, senescent cell antigen
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110829, 3987
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.51 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P48059, Q99JW4
Gene Symbols:
LIMS1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human LIMS1 (NP_0011804171)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Emerin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Emd
Gene Alias: AW550900, EDMD, EMD, Emerin, LEM domain containing 5, LEMD5, STA
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13726, 2010
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.03 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O08579, P50402
Gene Symbols: Emd
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Emerin/Emerin/EMD (NP_0001081)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Emerin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Emd
Gene Alias:
AW550900, EDMD, EMD, Emerin, LEM domain containing 5, LEMD5, STA
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13726, 2010
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.03 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O08579, P50402
Gene Symbols:
Emd
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Emerin/Emerin/EMD (NP_0001081)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG