PIPA589571

IFIT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA589571-Each-of-1 In Stock ₹ 45,218.46

PIPA589571 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

IFIT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFIT3

Gene Alias

cig41, CIG49, CIG-49, Garg49, GARG-49, Glucocorticoid-attenuated response gene 49 protein, Ifi49, IFI60, IFI-60K, IFIT3, IFIT-3, IFIT4, IFIT-4, interferon induced protein with tetratricopeptide repeats 3, interferon-induced 60 kDa protein, Interferon-induced protein with tetratricopeptide repeats 3, interferon-induced protein with tetratricopeptide repeats 4, interferon-stimulated protein 60, IRG2, Isg49, ISG60, ISG-60, P49, P60, retinoic acid-induced gene G protein, RIG-G, RP11-149I23.4

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15959, 309526, 3437

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O14879, Q64345

Gene Symbols

IFIT3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse IFIT3 (NP_0346311)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive Samples: HT-29, COS-7, Mouse liver; Cellular Location: Cytoplasm, Mitochondrion Immunogen sequence: YAWIYYHMGR LSEAQAYVDK VRQVCQKFAN PYSMECPELE CEEGWTRLKC GRNERAKMCF EKALEEKPKD PECSSGMAIA MFRLEEKPEK QFSVDALKQA M IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication
  • Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription
  • Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27
  • Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation
  • IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels
  • Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21
  • Can negatively regulate the apoptotic effects of IFIT2.

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Img

Thermo Scientific

PIPA589571

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Antigen:
IFIT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
cig41, CIG49, CIG-49, Garg49, GARG-49, Glucocorticoid-attenuated response gene 49 protein, Ifi49, IFI60, IFI-60K, IFIT3, IFIT-3, IFIT4, IFIT-4, interferon induced protein with tetratricopeptide repeats 3, interferon-induced 60 kDa protein, Interferon-induced protein with tetratricopeptide repeats 3, interferon-induced protein with tetratricopeptide repeats 4, interferon-stimulated protein 60, IRG2, Isg49, ISG60, ISG-60, P49, P60, retinoic acid-induced gene G protein, RIG-G, RP11-149I23.4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15959, 309526, 3437

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O14879, Q64345

Gene Symbols:
IFIT3

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse IFIT3 (NP_0346311)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589572

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Antigen:
IGF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF2

Gene Alias:
AL033362, C11orf43, FLJ22066, FLJ44734, GRDF, H-IGF-2, IGF, Igf2, Igf-2, IGFII, Igf-II, Insulin like growth factor, insulin like growth factor 2, insulin-like growth factor 2, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor II (IGF-II), Insulin-like growth factor II (somatomedin A), Insulin-like growth factor II Ala-25 Del, insulin-like growth factor II isoform 2 variant 4 preprotein, insulin-like growth factor type 2, M6pr, Mpr, MSA, multiplication-stimulating activity, Multiplication-stimulating polypeptide, Peg2, PP1446, PP9974, preptin, RNIGF2, Somatomedin-A, T3M-11-derived growth factor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16002, 24483, 3481

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
3.54 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P01344, P01346, P09535

Gene Symbols:
IGF2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-127 of human IGF2 (NP_0006031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589574

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Antigen:
FIBB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fgb

Gene Alias:
2510049G14Rik, Ab1-181, Ab1-216, Ac1-581, B beta polypeptide, beta-fibrinogen, epididymis secretory sperm binding protein Li 78p, Fgb, fibrinogen, Fibrinogen beta chain, fibrinogen, B beta polypeptide, fibrinogen, beta polypeptide, Fibrinopeptide B, HEL-S-78p, Liver regeneration-related protein LRRG036/LRRG043/LRRG189, MGC104327, MGC120405

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110135, 2244, 24366

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P02675, P14480, Q8K0E8

Gene Symbols:
Fgb

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-222 of human FGB (NP_0051322)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589575

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Antigen:
Kir2.3 (KCNJ4)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNJ4

Gene Alias:
BIR11, Brain inwardly rectifying K(+) channel 2, Hippocampal inward rectifier, hippocampal inward rectifier potassium channel, HIR, HIRK2, HRK1, Inward rectifier K(+) channel Kir2.3, inward rectifier potassium channel 4, IRK3, IRK-3, Kcnf2, KCNJ4, Kir 2.3, Kir2.3, MB-IRK3, Potassium channel, inwardly rectifying subfamily J member 4, potassium channel, inwardly rectifying subfamily J, member 4, potassium inwardly-rectifying channel, subfamily J, member 4, potassium voltage-gated channel subfamily J member 4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116649, 16520, 3761

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.6 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P48050, P52189, P52190

Gene Symbols:
KCNJ4

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ4 (NP_0049721)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG