PIPA589601
PTPN22 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589601-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA589601 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
PTPN22
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ptpn22
Gene Alias
70zpep, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, lymphoid-specific protein tyrosine phosphatase, LyP, LYP1, LYP2, PEP, PEST domain-enriched tyrosine phosphatase, PEST-domain phosphatase, protein tyrosine phosphatase, non-receptor type 22, protein tyrosine phosphatase, non-receptor type 22 (lymphoid), protein tyrosine phosphatase, non-receptor type 8, Ptpn22, PTPN8, tyrosine-phosphatase, Tyrosine-protein phosphatase non-receptor type 22
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19260, 26191, 295338
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.15 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P29352, Q9Y2R2
Gene Symbols
Ptpn22
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_0365434)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: MDQREILQKF LDEAQSKKIT KEEFANEFLK LKRQSTKYKA DKTYPTTVAE KPKNIKKNRY KDILPYDYSR VELSLITSDE DSSYINANFI; Positive Samples: Jurkat, Mouse spleen; Cellular Location: Cytoplasm The protein tyrosine phosphatase PTPN22 (PTP22, LYP, PEP, formerly PTPN8) is a genetic variant that confers risk of developing diverse human autoimmune diseases such as type 1 diabetes and rheumatoid arthritis
- The minor allele of a missense SNP in PTPN22 encodes a hematopoietic-specific protein tyrosine phosphatase also known as "eLyp."e The risk allele is present in about 17% of Caucasian individuals from the general population and in approximately 28% of Caucasian individuals with rheumatoid arthritis; it is thought to disrupt the P1 proline-rich motif that is important for interaction with the Src homology-3 (SH3) domain of CSK (cytoplasmic tyrosine kinase), potentially altering the normal functions of these proteins as negative regulators of T cell activation
- The interaction between CSK and PTPN22 is highly specific and it is speculated that PTPN22 may be an effector and/or regulator of CSK in T cells and other hematopoietic cells.
Compare Similar Items
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Antigen: PTPN22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ptpn22
Gene Alias: 70zpep, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, lymphoid-specific protein tyrosine phosphatase, LyP, LYP1, LYP2, PEP, PEST domain-enriched tyrosine phosphatase, PEST-domain phosphatase, protein tyrosine phosphatase, non-receptor type 22, protein tyrosine phosphatase, non-receptor type 22 (lymphoid), protein tyrosine phosphatase, non-receptor type 8, Ptpn22, PTPN8, tyrosine-phosphatase, Tyrosine-protein phosphatase non-receptor type 22
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19260, 26191, 295338
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.15 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P29352, Q9Y2R2
Gene Symbols: Ptpn22
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_0365434)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTPN22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ptpn22
Gene Alias:
70zpep, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, lymphoid-specific protein tyrosine phosphatase, LyP, LYP1, LYP2, PEP, PEST domain-enriched tyrosine phosphatase, PEST-domain phosphatase, protein tyrosine phosphatase, non-receptor type 22, protein tyrosine phosphatase, non-receptor type 22 (lymphoid), protein tyrosine phosphatase, non-receptor type 8, Ptpn22, PTPN8, tyrosine-phosphatase, Tyrosine-protein phosphatase non-receptor type 22
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19260, 26191, 295338
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.15 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P29352, Q9Y2R2
Gene Symbols:
Ptpn22
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_0365434)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF195
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF195
Gene Alias: HRF1, hypoxia-regulated factor-1, krueppel family zinc finger protein (znfp104), zinc finger protein 195, ZNF195, ZNFP104
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7748
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.14 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O14628
Gene Symbols: ZNF195
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ZNF195 (NP_0011239911)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF195
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF195
Gene Alias:
HRF1, hypoxia-regulated factor-1, krueppel family zinc finger protein (znfp104), zinc finger protein 195, ZNF195, ZNFP104
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7748
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.14 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O14628
Gene Symbols:
ZNF195
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ZNF195 (NP_0011239911)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NAPG
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NAPG
Gene Alias: 2400003O04Rik, gamma SNAP, GAMMASNAP, gamma-soluble NSF attachment protein, NAPG, N-ethylmaleimide sensitive fusion protein attachment protein gamma, N-ethylmaleimide-sensitive factor attachment protein gamma, N-ethylmaleimide-sensitive factor attachment protein, gamma, NSF attachment protein gamma, SNAPG, SNAP-gamma, SNARE, soluble NSF attachment protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 108123, 307382, 8774
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.47 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q99747, Q9CWZ7
Gene Symbols: NAPG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human NAPG (NP_0038171)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NAPG
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NAPG
Gene Alias:
2400003O04Rik, gamma SNAP, GAMMASNAP, gamma-soluble NSF attachment protein, NAPG, N-ethylmaleimide sensitive fusion protein attachment protein gamma, N-ethylmaleimide-sensitive factor attachment protein gamma, N-ethylmaleimide-sensitive factor attachment protein, gamma, NSF attachment protein gamma, SNAPG, SNAP-gamma, SNARE, soluble NSF attachment protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
108123, 307382, 8774
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.47 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q99747, Q9CWZ7
Gene Symbols:
NAPG
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human NAPG (NP_0038171)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FBP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FBP2
Gene Alias: D-fructose-1,6-bisphosphate 1-phosphohydrolase 2, Fbp1, Fbp-1, FBP2, FBPase, FBPase 2, FBPase muscle, fructose bisphosphatase 2, fructose-1, fructose-1,6-bisphosphatase 2, fructose-1,6-bisphosphatase isozyme 2, fructose-bisphosphatase 2, hexosediphosphatase, muscle FBPase, muscle fructose-bisphosphatase, Rae-30
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114508, 14120, 8789
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.35 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O00757, P70695, Q9Z1N1
Gene Symbols: FBP2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human FBP2 (NP_0038282)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FBP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FBP2
Gene Alias:
D-fructose-1,6-bisphosphate 1-phosphohydrolase 2, Fbp1, Fbp-1, FBP2, FBPase, FBPase 2, FBPase muscle, fructose bisphosphatase 2, fructose-1, fructose-1,6-bisphosphatase 2, fructose-1,6-bisphosphatase isozyme 2, fructose-bisphosphatase 2, hexosediphosphatase, muscle FBPase, muscle fructose-bisphosphatase, Rae-30
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114508, 14120, 8789
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O00757, P70695, Q9Z1N1
Gene Symbols:
FBP2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human FBP2 (NP_0038282)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG