PIPA589872
Nicastrin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589872-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA589872 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Nicastrin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NCSTN
Gene Alias
9430068N19Rik, AA727311, anterior pharynx-defective 2, Aph2, ATAG1874, D1Dau13e, Kiaa0253, mKIAA0253, NCSTN, Nct, Nicastrin, OTTHUMP00000031840, UNQ1874/PRO4317
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23385, 289231, 59287
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.69 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P57716, Q8CGU6, Q92542
Gene Symbols
NCSTN
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 429-669 of human NCSTN (NP_0561461)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: RFLRARNISG VVLADHSGAF HNKYYQSIYD TAENINVSYP EWLSPEEDLN FVTDTAKALA DVATVLGRAL YELAGGTNFS DTVQADPQTV TRLLYGFLIK ANNSWFQSIL RQDLRSYLGD GPLQHYIAVS SPTNTTYVVQ YALANLTGTV VNLTREQCQD PSKVPSENKD LYEYSWVQGP LHSNETDRLP RCVRSTARLA RALSPAFELS QWSSTEYSTW TESRWKDIRA RIFLIASKEL E; Positive Samples: Mouse brain, Rat brain, Rat spleen; Cellular Location: Melanosome, Membrane, Single-pass type I membrane protein NCSTN (Nicastrin) is a gene that encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex
- The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly
- The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain
- Mutations in this gene are associated with familial acne inversa
- A pseudogene of this gene is present on chromosome 21.
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Antigen: Nicastrin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NCSTN
Gene Alias: 9430068N19Rik, AA727311, anterior pharynx-defective 2, Aph2, ATAG1874, D1Dau13e, Kiaa0253, mKIAA0253, NCSTN, Nct, Nicastrin, OTTHUMP00000031840, UNQ1874/PRO4317
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23385, 289231, 59287
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.69 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P57716, Q8CGU6, Q92542
Gene Symbols: NCSTN
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 429-669 of human NCSTN (NP_0561461)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Nicastrin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NCSTN
Gene Alias:
9430068N19Rik, AA727311, anterior pharynx-defective 2, Aph2, ATAG1874, D1Dau13e, Kiaa0253, mKIAA0253, NCSTN, Nct, Nicastrin, OTTHUMP00000031840, UNQ1874/PRO4317
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23385, 289231, 59287
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.69 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P57716, Q8CGU6, Q92542
Gene Symbols:
NCSTN
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 429-669 of human NCSTN (NP_0561461)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PES1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pes1
Gene Alias: HAMAP-Rule:MF_03028}, Pes, PES1, Pescadillo homolog, pescadillo homolog {ECO:0000255, pescadillo homolog 1, containing BRCT domain, pescadillo homolog 1, containing BRCT domain (zebrafish), pescadillo ribosomal biogenesis factor 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23481
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.22 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O00541
Gene Symbols: Pes1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PES1 (NP_0551181)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PES1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pes1
Gene Alias:
HAMAP-Rule:MF_03028}, Pes, PES1, Pescadillo homolog, pescadillo homolog {ECO:0000255, pescadillo homolog 1, containing BRCT domain, pescadillo homolog 1, containing BRCT domain (zebrafish), pescadillo ribosomal biogenesis factor 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23481
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.22 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O00541
Gene Symbols:
Pes1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PES1 (NP_0551181)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZAK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K20
Gene Alias: AV006891, AZK, B230120H23Rik, HCCS4, HCCS-4, Human cervical cancer suppressor gene 4 protein, leucine zipper- and sterile alpha motif kinase ZAK, Leucine zipper- and sterile alpha motif-containing kinase, Map3k20, Mitogen-activated protein kinase kinase kinase 20, Mitogen-activated protein kinase kinase kinase MLT, mixed lineage kinase 7, mixed lineage kinase with a leucine zipper and a sterile alpha motif, mixed lineage kinase-related kinase, mixed lineage kinase-related kinase MRK-beta, MLK7, mLklak, MLK-like mitogen-activated protein triple kinase, MLK-related kinase, MLT, MLTK, MLTKalpha, MLTKbeta, MRK, pk, RGD1561394, SFMMP, sterile alpha motif and leucine zipper containing kinase AZK, sterile alpha motif- and leucine zipper-containing kinase AZK, sterile-alpha motif and leucine zipper containing kinase AZK, ZAK
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311743, 65964
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.76 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9ESL4
Gene Symbols: MAP3K20
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-312 of human ZAK (NP_5984071)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ZAK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K20
Gene Alias:
AV006891, AZK, B230120H23Rik, HCCS4, HCCS-4, Human cervical cancer suppressor gene 4 protein, leucine zipper- and sterile alpha motif kinase ZAK, Leucine zipper- and sterile alpha motif-containing kinase, Map3k20, Mitogen-activated protein kinase kinase kinase 20, Mitogen-activated protein kinase kinase kinase MLT, mixed lineage kinase 7, mixed lineage kinase with a leucine zipper and a sterile alpha motif, mixed lineage kinase-related kinase, mixed lineage kinase-related kinase MRK-beta, MLK7, mLklak, MLK-like mitogen-activated protein triple kinase, MLK-related kinase, MLT, MLTK, MLTKalpha, MLTKbeta, MRK, pk, RGD1561394, SFMMP, sterile alpha motif and leucine zipper containing kinase AZK, sterile alpha motif- and leucine zipper-containing kinase AZK, sterile-alpha motif and leucine zipper containing kinase AZK, ZAK
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311743, 65964
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.76 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9ESL4
Gene Symbols:
MAP3K20
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-312 of human ZAK (NP_5984071)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NALP12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLRP12
Gene Alias: CLR19.3, FCAS2, monarch 1, monarch-1, NACHT, leucine rich repeat and PYD containing 12, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, NALP12, NLR family pyrin domain containing 12, NLR family, pyrin domain containing 12, Nlrp12, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12, PAN6, PYPAF7, PYRIN-containing APAF1-like protein 7, regulated by nitric oxide, RNO, RNO2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 292541, 91662
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.07 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P59046
Gene Symbols: NLRP12
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 862-1061 of human NLRP12 (NP_6532881)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NALP12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLRP12
Gene Alias:
CLR19.3, FCAS2, monarch 1, monarch-1, NACHT, leucine rich repeat and PYD containing 12, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, NALP12, NLR family pyrin domain containing 12, NLR family, pyrin domain containing 12, Nlrp12, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12, PAN6, PYPAF7, PYRIN-containing APAF1-like protein 7, regulated by nitric oxide, RNO, RNO2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
292541, 91662
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.07 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P59046
Gene Symbols:
NLRP12
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 862-1061 of human NLRP12 (NP_6532881)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG