PIPA590243
RNAse H2A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA590243-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA590243 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
RNAse H2A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RNASEH2A
Gene Alias
2400006P09Rik, AGS4, Aicardi-Goutieres syndrome 4 protein, hypothetical protein LOC512830, hypothetical protein MGC56307, JUNB, ribonuclease H2 subunit A, ribonuclease H2, large subunit, ribonuclease H2, subunit A, ribonuclease HI, ribonuclease HI large subunit, Ribonuclease HI subunit A, ribonuclease HI, large subunit, RNase H(35), RNase H2 subunit A, RNase HI large subunit, Rnaseh2a, RNASEHI, RNHIA, RNHL, zgc:56307
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10535, 364974
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.57 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O75792, Q5U209
Gene Symbols
RNASEH2A
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_0063882)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MDLSELERDN TGRCRLSSPV PAVCRKEPCV LGVDEAGRGP VLGPMVYAIC YCPLPRLADL EALKVADSKT LLESERERLF AKMEDTDFVG WALDVLSPNL ISTSMLGRVK YNLNSLSHDT ATGLIQYALD QGVNVTQVFV DTVGMPETYQ ARLQQSFPGI EVTVKAKADA LYPVVSAASI CAKVARDQAV KKWQFVEKLQ DLDTDYGSGY PNDPKTKAWL KEHVEPVFGF PQFVRFSWRT AQTILEKEAE DVIWEDSASE NQEGLRKITS YFLNEGSQAR PRSSHRYFLE RGLESATSL; Positive Samples: rat ovary, rat testis, rat liver; Cellular Location: Nucleus Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids
- The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair
- RNAse H2 is made up of three subunits; all three are required for RNAse activity
- Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid
- Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
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Antigen: RNAse H2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RNASEH2A
Gene Alias: 2400006P09Rik, AGS4, Aicardi-Goutieres syndrome 4 protein, hypothetical protein LOC512830, hypothetical protein MGC56307, JUNB, ribonuclease H2 subunit A, ribonuclease H2, large subunit, ribonuclease H2, subunit A, ribonuclease HI, ribonuclease HI large subunit, Ribonuclease HI subunit A, ribonuclease HI, large subunit, RNase H(35), RNase H2 subunit A, RNase HI large subunit, Rnaseh2a, RNASEHI, RNHIA, RNHL, zgc:56307
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10535, 364974
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.57 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O75792, Q5U209
Gene Symbols: RNASEH2A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_0063882)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RNAse H2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RNASEH2A
Gene Alias:
2400006P09Rik, AGS4, Aicardi-Goutieres syndrome 4 protein, hypothetical protein LOC512830, hypothetical protein MGC56307, JUNB, ribonuclease H2 subunit A, ribonuclease H2, large subunit, ribonuclease H2, subunit A, ribonuclease HI, ribonuclease HI large subunit, Ribonuclease HI subunit A, ribonuclease HI, large subunit, RNase H(35), RNase H2 subunit A, RNase HI large subunit, Rnaseh2a, RNASEHI, RNHIA, RNHL, zgc:56307
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10535, 364974
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.57 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O75792, Q5U209
Gene Symbols:
RNASEH2A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_0063882)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TRAM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tram1
Gene Alias: 1810049E02Rik, PNAS8, TRAM, Tram1, TRAMP, Translocating chain-associated membrane protein 1, translocating chain-associating membrane protein, translocating chain-associating membrane protein 1, translocation associated membrane protein 1, translocation-associating membrane protein 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23471, 72265
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.15 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q15629, Q91V04
Gene Symbols: Tram1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human TRAM1 (NP_0551091)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TRAM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tram1
Gene Alias:
1810049E02Rik, PNAS8, TRAM, Tram1, TRAMP, Translocating chain-associated membrane protein 1, translocating chain-associating membrane protein, translocating chain-associating membrane protein 1, translocation associated membrane protein 1, translocation-associating membrane protein 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23471, 72265
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.15 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q15629, Q91V04
Gene Symbols:
Tram1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human TRAM1 (NP_0551091)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: HEY2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hey2
Gene Alias: basic helix-loop-helix transcription factor, bHLHb32, cardiovascular basic helix-loop-helix factor 1, cardiovascular helix-loop-helix factor 1, Chf1, Class B basic helix-loop-helix protein 32, gridlock, GRL, h hHRT2, hairy and enhancer of split related 2, hairy and enhancer of split-related protein 2, hairy/enhancer-of-split related with YRPW motif 2, hairy/enhancer-of-split related with YRPW motif protein 2, Hairy-E(spl)-related with YRPW motif 2, hairy-related transcription factor 2, hCHF1, HERP, Herp1, Herp2, hes related family bHLH transcription factor with YRPW motif 2, hesr2, HESR-2, hes-related family bHLH transcription factor with YRPW motif 2, HES-related repressor protein 1, HES-related repressor protein 2, hey2, hHRT2, Hrt2, HRT-2, mHRT2, protein gridlock, Protein gridlock homolog, zgc:136746
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15214, 155430, 23493
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.98 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q9QUS4, Q9UBP5
Gene Symbols: Hey2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_0363911)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HEY2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hey2
Gene Alias:
basic helix-loop-helix transcription factor, bHLHb32, cardiovascular basic helix-loop-helix factor 1, cardiovascular helix-loop-helix factor 1, Chf1, Class B basic helix-loop-helix protein 32, gridlock, GRL, h hHRT2, hairy and enhancer of split related 2, hairy and enhancer of split-related protein 2, hairy/enhancer-of-split related with YRPW motif 2, hairy/enhancer-of-split related with YRPW motif protein 2, Hairy-E(spl)-related with YRPW motif 2, hairy-related transcription factor 2, hCHF1, HERP, Herp1, Herp2, hes related family bHLH transcription factor with YRPW motif 2, hesr2, HESR-2, hes-related family bHLH transcription factor with YRPW motif 2, HES-related repressor protein 1, HES-related repressor protein 2, hey2, hHRT2, Hrt2, HRT-2, mHRT2, protein gridlock, Protein gridlock homolog, zgc:136746
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15214, 155430, 23493
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q9QUS4, Q9UBP5
Gene Symbols:
Hey2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_0363911)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: KLHDC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Klhdc2
Gene Alias: 2310022K15Rik, D12Ertd522e, endothelial differentiation inhibitory protein TNG, HCA33, HCLP1, HCLP-1, Hepatocellular carcinoma-associated antigen 33, host cell factor homolog LCP, Host cell factor-like protein 1, kelch domain containing 2, kelch domain-containing protein 2, KLHDC2, LCP, similar to kelch domain containing 2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23588, 299113, 69554
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.46 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q3KRE6, Q4G5Y1, Q9Y2U9
Gene Symbols: Klhdc2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 306-406 of human KLHDC2 (NP_0551301)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
KLHDC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Klhdc2
Gene Alias:
2310022K15Rik, D12Ertd522e, endothelial differentiation inhibitory protein TNG, HCA33, HCLP1, HCLP-1, Hepatocellular carcinoma-associated antigen 33, host cell factor homolog LCP, Host cell factor-like protein 1, kelch domain containing 2, kelch domain-containing protein 2, KLHDC2, LCP, similar to kelch domain containing 2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23588, 299113, 69554
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.46 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q3KRE6, Q4G5Y1, Q9Y2U9
Gene Symbols:
Klhdc2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 306-406 of human KLHDC2 (NP_0551301)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG