PIPA590399

MTMR6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA590399-Each-of-1 In Stock ₹ 44,277.30

PIPA590399 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

MTMR6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MTMR6

Gene Alias

4022440C11Rik, AI428804, AU041072, MTMR6, myotubularin related protein 6, Myotubularin-like protein 6-like protein, myotubularin-related protein 6, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

219135, 305935, 9107

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.03 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q8VE11, Q9Y217

Gene Symbols

MTMR6

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 382-621 of human MTMR6 (NP_0046763)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RCGQLDGDPK EVSPVFTQFL ECVWHLTEQF PQAFEFSEAF LLQIHEHIHS CQFGNFLGNC QKEREELKLK EKTYSLWPFL LEDQKKYLNP LYSSESHRFT VLEPNTVSFN FKFWRNMYHQ FDRTLHPRQS VFNIIMNMNE QNKQLEKDIK DLESKIKQRK NKQTDGILTK ELLHSVHPES PNLKTSLCFK EQTLLPVNDA LRTIEGSSPA DNRYSEYAEE FSKSEPAVVS LEYGVARMTC; Positive Samples: HepG2, HeLa, 293T, Mouse heart, Mouse brain, Mouse lung, Mouse spleen, Mouse testis, Rat heart; Cellular Location: Nucleus envelope Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:19038970, PubMed:22647598)
  • Dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,5-bisphosphate (PubMed:19038970, PubMed:22647598) (Probable)
  • Binds with high affinity to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) but also to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), phosphatidic acid and phosphatidylserine (PubMed:19038970)
  • Negatively regulates ER-Golgi protein transport
  • Probably in association with MTMR9, plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3-phosphate in membrane ruffles (PubMed:24591580)
  • Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4(+) T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3-phosphate (PubMed:15831468)
  • Negatively regulates proliferation of reactivated CD4(+) T-cells (PubMed:16847315)
  • In complex with MTMR9, negatively regulates DNA damage-induced apoptosis (PubMed:19038970, PubMed:22647598)
  • The formation of the MTMR6-MTMR9 complex stabilizes both MTMR6 and MTMR9 protein levels (PubMed:19038970)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA590399

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Antigen:
MTMR6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTMR6

Gene Alias:
4022440C11Rik, AI428804, AU041072, MTMR6, myotubularin related protein 6, Myotubularin-like protein 6-like protein, myotubularin-related protein 6, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
219135, 305935, 9107

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.03 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8VE11, Q9Y217

Gene Symbols:
MTMR6

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 382-621 of human MTMR6 (NP_0046763)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA590402

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Antigen:
Cytohesin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYTH1

Gene Alias:
B2-1, CLM1, CTH-1, CYTH1, CYTIP, cytoadhesin 1, cytohesin 1, CYTOHESIN-1, D17S811E, FLJ34050, FLJ41900, homolog of secretory protein SEC7, mKIAA4240, mSec7-1, PH, SEC7 and coiled-coil domain-containing protein 1, pleckstrin homology, Sec7 and coiled/coil domains 1(cytohesin 1), pleckstrin homology, Sec7 and coiled-coil domains 1, Pscd1, rSec7-1, SEC7, SEC7 homolog A, SEC7 homolog B2-1, Sec7a

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116691, 19157, 9267

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P97694, Q15438, Q9QX11

Gene Symbols:
CYTH1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH1 (NP_0047531)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA590403

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Antigen:
ASC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Trip4

Gene Alias:
4930558E03Rik, Activating signal cointegrator 1, Asc1, ASC-1, BB191711, HsT17391, SMABF1, thyroid hormone receptor interactor 4, thyroid receptor-interacting protein 4, transcription coactivator Asc1, TR-interacting protein 4, TRIP4, TRIP-4, ZC2HC5, zinc finger, C2HC5-type

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
315769, 56404, 9325

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.94 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q15650, Q9QXN3

Gene Symbols:
Trip4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human TRIP4 (NP_0572972)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA590404

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Antigen:
SLIT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLIT2

Gene Alias:
downregulated during adipocyte differentiation-1, Drad-1, E030015M03Rik, E130320P19Rik, mKIAA4141, neurogenic extracellular slit protein, SLIL3, Slit, slit guidance ligand 2, slit homolog 2 (Drosophila), slit homolog 2 protein, Slit homolog 2 protein C-product, Slit homolog 2 protein N-product, SLIT2, Slit-2, Slit2 protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20563, 9353

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.72 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O94813, Q9R1B9

Gene Symbols:
SLIT2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1330-1529 of human Slit2 (NP_0047781)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG