PIPA590579
GPR109 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | PIPA590579-Each | In Stock | ₹ 38,300.93 |
PIPA590579 - Each
In Stock
Quantity
1
Base Price: ₹ 38,300.93
GST (18%): ₹ 6,894.167
Total Price: ₹ 45,195.097
Antigen
GPR109
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HCAR2
Gene Alias
G protein-coupled receptor 109A, G protein-coupled receptor 109B, G protein-coupled receptor HM74a, Gpr109, Gpr109a, Gpr109b, G-protein coupled receptor 109, G-protein coupled receptor 109A, G-protein coupled receptor HM74, G-protein coupled receptor HM74A, HCA2, Hcar2, HM74, HM74a, HM74b, hydroxycarboxylic acid receptor 2, hydroxy-carboxylic acid receptor 2, interferon-gamma inducible gene, Puma-g, mHM74b, Niacin receptor 1, Niacr1, Nicotinic acid receptor, Protein PUMA-G, PUMAG, PUMA-G, PUMA-G. GPR109, putative seven transmembrane spanning receptor
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
338442, 369160, 80885
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
Q80Z39, Q8TDS4, Q9EP66
Gene Symbols
HCAR2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GPR109A/HM74A/HCAR2 (NP_8082191)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KKMPIQNGGA NLCSSFSI Positive Samples: HepG2, Rat heart GPR109A (also known as HCA2, HM74a, and NIACR1) is a 42kDa G-protein coupled receptor that belongs to a family of three hydroxyl-carboxylic acid receptors, which also include GPR109B and GPR81
- GPR109A has two known ligands: niacin and butyrate (or its derivative 3-hydroxybutyrate)
- The endogenous ligands for GPR109B and GPR81 are 3-hydroxyl-octanoic acid and 2-hydroxy-propanoate (lactate), respectively
- GPR109A is expressed on adipocytes, neutrophils, Langerhans cells, keratinocytes, intestinal epithelial cells, and intestinal colonic macrophages
- Niacin, also known as nicotinic acid or vitamin B3, is known to improve cholesterol metabolism (LDL/HDL ratio) and reduce inflammation
- It has been demonstrated that this effect is mediated through GPR109A
- Notably, GPR109A also has an essential role in suppressing inflammation and cancer in the colon
- Both GPR109A ligands are produced by colonic commensal bacteria
- In mice, GPR109A expression on intestinal epithelial cells and DCs/macrophages contributes to the suppression of colitis and colon cancer
- In humans, GPR109A is silenced in colon carcinoma cells by DNA methylation, which increases inflammation in the intestinal tract.
Compare Similar Items
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Antigen: GPR109
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HCAR2
Gene Alias: G protein-coupled receptor 109A, G protein-coupled receptor 109B, G protein-coupled receptor HM74a, Gpr109, Gpr109a, Gpr109b, G-protein coupled receptor 109, G-protein coupled receptor 109A, G-protein coupled receptor HM74, G-protein coupled receptor HM74A, HCA2, Hcar2, HM74, HM74a, HM74b, hydroxycarboxylic acid receptor 2, hydroxy-carboxylic acid receptor 2, interferon-gamma inducible gene, Puma-g, mHM74b, Niacin receptor 1, Niacr1, Nicotinic acid receptor, Protein PUMA-G, PUMAG, PUMA-G, PUMA-G. GPR109, putative seven transmembrane spanning receptor
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 338442, 369160, 80885
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q80Z39, Q8TDS4, Q9EP66
Gene Symbols: HCAR2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GPR109A/HM74A/HCAR2 (NP_8082191)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GPR109
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HCAR2
Gene Alias:
G protein-coupled receptor 109A, G protein-coupled receptor 109B, G protein-coupled receptor HM74a, Gpr109, Gpr109a, Gpr109b, G-protein coupled receptor 109, G-protein coupled receptor 109A, G-protein coupled receptor HM74, G-protein coupled receptor HM74A, HCA2, Hcar2, HM74, HM74a, HM74b, hydroxycarboxylic acid receptor 2, hydroxy-carboxylic acid receptor 2, interferon-gamma inducible gene, Puma-g, mHM74b, Niacin receptor 1, Niacr1, Nicotinic acid receptor, Protein PUMA-G, PUMAG, PUMA-G, PUMA-G. GPR109, putative seven transmembrane spanning receptor
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
338442, 369160, 80885
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q80Z39, Q8TDS4, Q9EP66
Gene Symbols:
HCAR2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GPR109A/HM74A/HCAR2 (NP_8082191)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NDUFB11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NDUFB11
Gene Alias: CI-ESSS, complex I NP17.3 subunit, complex I-ESSS, D5Bwg0566e, D5Bwg0577e, ESSS, LSDMCA3, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial, NADH:ubiquinone oxidoreductase subunit B11, NADH-ubiquinone oxidoreductase ESSS subunit, NDUFB11, Neuronal protein 15.6, neuronal protein 17.3, Np15, NP15.6, Np17.3, nuclear protein 15.6, p15.6, P17.3, RGD1563698, UNQ111/PRO1064
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 104130, 299310, 54539
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.11 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O09111, Q9NX14
Gene Symbols: NDUFB11
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human NDUFB11 (NP_0619292)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NDUFB11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NDUFB11
Gene Alias:
CI-ESSS, complex I NP17.3 subunit, complex I-ESSS, D5Bwg0566e, D5Bwg0577e, ESSS, LSDMCA3, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial, NADH:ubiquinone oxidoreductase subunit B11, NADH-ubiquinone oxidoreductase ESSS subunit, NDUFB11, Neuronal protein 15.6, neuronal protein 17.3, Np15, NP15.6, Np17.3, nuclear protein 15.6, p15.6, P17.3, RGD1563698, UNQ111/PRO1064
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104130, 299310, 54539
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.11 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O09111, Q9NX14
Gene Symbols:
NDUFB11
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human NDUFB11 (NP_0619292)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TrkA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ntrk1
Gene Alias: C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18211, 4914, 59109
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.99 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P04629, P35739, Q3UFB7
Gene Symbols: Ntrk1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-796 of human TrkA (NP_0025202)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TrkA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ntrk1
Gene Alias:
C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18211, 4914, 59109
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.99 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P04629, P35739, Q3UFB7
Gene Symbols:
Ntrk1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-796 of human TrkA (NP_0025202)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Angiotensinogen
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AGT
Gene Alias: AGT, AI265500, alpha-1 antiproteinase, antitrypsin, Ang, Ang I, Ang II, Ang III, Ang IV, AngI, AngII, Angiotensin 1-10, Angiotensin 1-4, Angiotensin 1-5, Angiotensin 1-7, Angiotensin 1-8, Angiotensin 1-9, Angiotensin 2-8, Angiotensin 3-8, Angiotensin I, angiotensin II, Angiotensin III, Angiotensin IV, angiotensin ll, Angiotensin-1, Angiotensin-2, Angiotensin-3, Angiotensin-4, Angiotensinogen, angiotensinogen (PAT), angiotensinogen (serpin peptidase inhibitor, clade A, member 8), ANHU, ANRT, Aogen, Des-Asp[1]-angiotensin II, PAT, pre-angiotensinogen, serine (or cysteine) proteinase inhibitor, serpin A8, serpin peptidase inhibitor, clade A, member 8, Serpina8
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11606, 183, 24179
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.10 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P01015, P01019, P11859
Gene Symbols: AGT
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 35-485 of human Angiotensinogen (NP_0000201)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Angiotensinogen
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AGT
Gene Alias:
AGT, AI265500, alpha-1 antiproteinase, antitrypsin, Ang, Ang I, Ang II, Ang III, Ang IV, AngI, AngII, Angiotensin 1-10, Angiotensin 1-4, Angiotensin 1-5, Angiotensin 1-7, Angiotensin 1-8, Angiotensin 1-9, Angiotensin 2-8, Angiotensin 3-8, Angiotensin I, angiotensin II, Angiotensin III, Angiotensin IV, angiotensin ll, Angiotensin-1, Angiotensin-2, Angiotensin-3, Angiotensin-4, Angiotensinogen, angiotensinogen (PAT), angiotensinogen (serpin peptidase inhibitor, clade A, member 8), ANHU, ANRT, Aogen, Des-Asp[1]-angiotensin II, PAT, pre-angiotensinogen, serine (or cysteine) proteinase inhibitor, serpin A8, serpin peptidase inhibitor, clade A, member 8, Serpina8
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11606, 183, 24179
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.10 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P01015, P01019, P11859
Gene Symbols:
AGT
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-485 of human Angiotensinogen (NP_0000201)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG