PIPA590705
FSTL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA590705-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA590705 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
FSTL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Fstl1
Gene Alias
AI316791, AW107808, FLJ50214, FLJ52277, follistatin like 1, follistatin-like 1, follistatin-like protein 1, Follistatin-related protein 1, FRP, FSL1, Fstl, FSTL1, MIR198, OCC1, OCC-1, TGF-beta-inducible protein TSC-36, tsc36, TSC-36
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11167, 14314, 79210
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.90 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q12841, Q62356, Q62632
Gene Symbols
Fstl1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_0090161)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MWKRWLALAL ALVAVAWVRA EEELRSKSKI CANVFCGAGR ECAVTEKGEP TCLCIEQCKP HKRPVCGSNG KTYLNHCELH RDACLTGSKI QVDYDGHCKE KKSVSPSASP VVCYQSNRDE LRRRIIQWLE AEIIPDGWFS KGSNYSEILD KYFKNFDNGD SRLDSSEFLK FVEQNETAIN ITTYPDQENN KLLRGLCVDA LIELSDENAD WKLSFQEFLK CLNPSFNPPE KKCALEDETY ADGAETEVDC NRCVCACGNW VCTAMTCDGK NQKGAQTQTE EEMTRYVQEL QKHQETAEKT KRVSTKEI; Positive Samples: Mouse heart, Mouse brain, Rat heart Follistatin-like protein 1 (FSTL1) is a widely-expressed, extracellular glycoprotein that is homologously grouped into the osteonectin (BM-40/SPARC) family of secreted proteins based on its possession of both a follistatin-like and extracellular calcium-binding domain
- Initially identified as a TGF-beta-inducible protein in a cloned mouse osteoblast cell line, FSTL1 has since been implicated in an array of cell-type-specific functions, such as the regulation of proliferation, differentiation, apoptosis and migration, as well as a number of biological processes, including embryonic development, inflammatory response, angiogenesis, tumorigenesis, and immune disease pathogenesis
- Highly conserved across mammalian species and widely expressed in human tissues, FSTL1 can be upregulated through signaling mediators of the innate immune system,such as TLR4 agonists and the arthritogenic cytokine IL-1beta via NFkappaB pathways, to stimulate the expression and secretion of pro-inflammatory cytokines, including TNF-alpha, IL-1beta, IL-6 and IL-8
- While cells of mesenchymal lineage are capable of FSTL1 production, FSTL1 expression is notably absent from cells of hematopoietic lineage under normal physiological conditions
- Macrophages and monocytes are, however, capable of taking up FSTL1 at sites of inflammation where FSTL1 stimulation can cause the expression of caspase-1 and its resultant enzymatic cleavage of active IL-1beta from pro-IL-1beta
- Whereas the overexpression of FSTL1 has been noted as a substantial contributor to the progression of immune diseases like rheumatoid arthritis (RA) and osteoarthritis (OA), diminished FSTL1 serum levels have been identified as playing a significant part in both ovarian and endometrial carcinogenesis, where it directly affects cell proliferation, migration and invasion.
Compare Similar Items
Show Difference
Antigen: FSTL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fstl1
Gene Alias: AI316791, AW107808, FLJ50214, FLJ52277, follistatin like 1, follistatin-like 1, follistatin-like protein 1, Follistatin-related protein 1, FRP, FSL1, Fstl, FSTL1, MIR198, OCC1, OCC-1, TGF-beta-inducible protein TSC-36, tsc36, TSC-36
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11167, 14314, 79210
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.90 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q12841, Q62356, Q62632
Gene Symbols: Fstl1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_0090161)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FSTL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fstl1
Gene Alias:
AI316791, AW107808, FLJ50214, FLJ52277, follistatin like 1, follistatin-like 1, follistatin-like protein 1, Follistatin-related protein 1, FRP, FSL1, Fstl, FSTL1, MIR198, OCC1, OCC-1, TGF-beta-inducible protein TSC-36, tsc36, TSC-36
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11167, 14314, 79210
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.90 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q12841, Q62356, Q62632
Gene Symbols:
Fstl1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_0090161)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HLA-DRA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HLA-DRA
Gene Alias: histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3122
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.07 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P01903
Gene Symbols: HLA-DRA
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human HLA-DRA (NP_0619842)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HLA-DRA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HLA-DRA
Gene Alias:
histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3122
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.07 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P01903
Gene Symbols:
HLA-DRA
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human HLA-DRA (NP_0619842)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GPR45
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GPR45
Gene Alias: 9230112G11Rik, AW046772, G protein-coupled receptor 45, GPR45, high-affinity lysophosphatidic acid receptor, probable G-protein coupled receptor 45, PSP24, PSP24(ALPHA), PSP24-1, PSP24A, PSP24alpha, PSP24-alpha
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11250
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.41 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9Y5Y3
Gene Symbols: GPR45
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR45 (NP_0091583)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GPR45
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GPR45
Gene Alias:
9230112G11Rik, AW046772, G protein-coupled receptor 45, GPR45, high-affinity lysophosphatidic acid receptor, probable G-protein coupled receptor 45, PSP24, PSP24(ALPHA), PSP24-1, PSP24A, PSP24alpha, PSP24-alpha
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11250
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.41 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9Y5Y3
Gene Symbols:
GPR45
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR45 (NP_0091583)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: LYPLA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LYPLA2
Gene Alias: Acyl-protein thioesterase 2, APT2, APT-2, DJ886K2.4, LPL-II, Lypla2, LysoII, Lysophospholipase 2, lysophospholipase II, lysoPLA II, mLyso II, testicular tissue protein Li 3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11313, 26394, 83510
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.39 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O95372, Q9QYL8, Q9WTL7
Gene Symbols: LYPLA2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_0091911)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LYPLA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LYPLA2
Gene Alias:
Acyl-protein thioesterase 2, APT2, APT-2, DJ886K2.4, LPL-II, Lypla2, LysoII, Lysophospholipase 2, lysophospholipase II, lysoPLA II, mLyso II, testicular tissue protein Li 3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11313, 26394, 83510
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.39 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O95372, Q9QYL8, Q9WTL7
Gene Symbols:
LYPLA2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_0091911)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG