PIPA590794
MYOC Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA590794-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA590794 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MYOC
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MYOC
Gene Alias
AI957332, GLC1A, GPOA, JOAG, JOAG1, juvenile-onset open-angle glaucoma 1, mutated trabecular meshwork-induced glucocorticoid response protein, MYOC, Myocilin, Myocilin 20 kDa N-terminal fragment, Myocilin 35 kDa N-terminal fragment, Myocilin 55 kDa subunit, myocilin trabecular meshwork inducible glucocorticoid response, myocilin trabecular meshwork inducible glucocorticoid response protein, Myocilin, C-terminal fragment, Myocilin, N-terminal fragment, myocilin, trabecular meshwork inducible glucocorticoid response, TIGR, trabecular meshwork inducible glucocorticoid response protein, trabecular meshwork-induced glucocorticoid response protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17926, 4653
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.46 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O70624, Q99972
Gene Symbols
MYOC
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_0002521)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: CGELVWVGEP LTLRTAETIT GKYGVWMRDP KPTYPYTQET TWRIDTVGTD VRQVFEYDLI SQFMQGYPSK VHILPRPLES TGAVVYSGSL YFQGAESRTV IRYELNTETV KAEKEIPGAG YHGQFPYSWG GYTDIDLAVD EAGLWVIYST DEAKGAIVLS KLNPENLELE QTWETNIRKQ SVANAFIICG TLYTVSSYTS ADATVNFAYD TGTGISKTLT IPFKNRYKYS SMIDYNPLEK KLFAWDNLNM VTYDIKLSKM; Positive Samples: Raji, U-937, BT-474, Mouse brain; Cellular Location: Cell projection, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Mitochondrion, Mitochondrion inner membrane, Mitochondrion intermembrane space, Mitochondrion outer membrane, Rough endoplasmic reticulum, cilium, exosome, extracellular matrix, extracellular space Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body
- Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1
- In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex
- This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP)
- Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness
- Myocilin is encoded by MYOC (also designated TIGR), a gene that maps to the GLC1A locus on chromosome 1q24
- 3 and is susceptible to mutations
- Mutations in the MYOC gene are specifically linked with primary open angle glaucoma (POAG), a blinding disease characterized by progressive loss of retinal ganglion cells.
Compare Similar Items
Show Difference
Antigen: MYOC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYOC
Gene Alias: AI957332, GLC1A, GPOA, JOAG, JOAG1, juvenile-onset open-angle glaucoma 1, mutated trabecular meshwork-induced glucocorticoid response protein, MYOC, Myocilin, Myocilin 20 kDa N-terminal fragment, Myocilin 35 kDa N-terminal fragment, Myocilin 55 kDa subunit, myocilin trabecular meshwork inducible glucocorticoid response, myocilin trabecular meshwork inducible glucocorticoid response protein, Myocilin, C-terminal fragment, Myocilin, N-terminal fragment, myocilin, trabecular meshwork inducible glucocorticoid response, TIGR, trabecular meshwork inducible glucocorticoid response protein, trabecular meshwork-induced glucocorticoid response protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17926, 4653
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.46 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O70624, Q99972
Gene Symbols: MYOC
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_0002521)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MYOC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYOC
Gene Alias:
AI957332, GLC1A, GPOA, JOAG, JOAG1, juvenile-onset open-angle glaucoma 1, mutated trabecular meshwork-induced glucocorticoid response protein, MYOC, Myocilin, Myocilin 20 kDa N-terminal fragment, Myocilin 35 kDa N-terminal fragment, Myocilin 55 kDa subunit, myocilin trabecular meshwork inducible glucocorticoid response, myocilin trabecular meshwork inducible glucocorticoid response protein, Myocilin, C-terminal fragment, Myocilin, N-terminal fragment, myocilin, trabecular meshwork inducible glucocorticoid response, TIGR, trabecular meshwork inducible glucocorticoid response protein, trabecular meshwork-induced glucocorticoid response protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17926, 4653
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.46 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O70624, Q99972
Gene Symbols:
MYOC
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_0002521)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DDX31
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ddx31
Gene Alias: 5830444G11Rik, DDX31, DEAD (Asp-Glu-Ala-Asp) box polypeptide 31, DEAD box protein 31, DEAD/DEXH helicase DDX31, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31, DEAD-box helicase 31, G2 helicase, Gm997, Helicain, PPP1R25, Probable ATP-dependent RNA helicase DDX31, protein phosphatase 1, regulatory subunit 25
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 227674, 311835, 64794
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.34 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q6NZQ2, Q9H8H2
Gene Symbols: Ddx31
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 652-851 of human DDX31 (NP_0736166)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DDX31
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ddx31
Gene Alias:
5830444G11Rik, DDX31, DEAD (Asp-Glu-Ala-Asp) box polypeptide 31, DEAD box protein 31, DEAD/DEXH helicase DDX31, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31, DEAD-box helicase 31, G2 helicase, Gm997, Helicain, PPP1R25, Probable ATP-dependent RNA helicase DDX31, protein phosphatase 1, regulatory subunit 25
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
227674, 311835, 64794
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.34 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q6NZQ2, Q9H8H2
Gene Symbols:
Ddx31
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 652-851 of human DDX31 (NP_0736166)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: B3GNT4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: B3GNT4
Gene Alias: 1010001G17Rik, B3GNT4, B3GN-T4, beta-1,3-Gn-T4, beta-1,3-N-acetylglucosaminyltransferase 4, beta-1,3-N-acetylglucosaminyltransferase bGn-T4, beta3Gn-T4, BGnT-4, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, UNQ1898/PRO4344
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 231727, 288752, 79369
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.38 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q1RLK6, Q9C0J1
Gene Symbols: B3GNT4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 165-305 of human B3GNT4 (NP_1103921)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
B3GNT4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
B3GNT4
Gene Alias:
1010001G17Rik, B3GNT4, B3GN-T4, beta-1,3-Gn-T4, beta-1,3-N-acetylglucosaminyltransferase 4, beta-1,3-N-acetylglucosaminyltransferase bGn-T4, beta3Gn-T4, BGnT-4, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, UNQ1898/PRO4344
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231727, 288752, 79369
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.38 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q1RLK6, Q9C0J1
Gene Symbols:
B3GNT4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-305 of human B3GNT4 (NP_1103921)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ASB13
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ASB13
Gene Alias: 2210015B19Rik, 6430573K02Rik, ankyrin repeat and SOCS box containing 13, ankyrin repeat and SOCS box protein 13, ankyrin repeat and SOCS box-containing 13, ankyrin repeat and SOCS box-containing protein 13, ankyrin repeat domain-containing SOCS box protein 13, ankyrin repeat domain-containing SOCS box protein Asb-13, ASB13, Asb-13, C85285
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 142688, 361268, 79754
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.58 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q8VBX0, Q8WXK3
Gene Symbols: ASB13
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human ASB13 (NP_0789772)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ASB13
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ASB13
Gene Alias:
2210015B19Rik, 6430573K02Rik, ankyrin repeat and SOCS box containing 13, ankyrin repeat and SOCS box protein 13, ankyrin repeat and SOCS box-containing 13, ankyrin repeat and SOCS box-containing protein 13, ankyrin repeat domain-containing SOCS box protein 13, ankyrin repeat domain-containing SOCS box protein Asb-13, ASB13, Asb-13, C85285
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
142688, 361268, 79754
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q8VBX0, Q8WXK3
Gene Symbols:
ASB13
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human ASB13 (NP_0789772)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG