PIPA590885

Di-Methyl-DNMT3A (Lys44) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA590885-Each-of-1 In Stock ₹ 45,047.34

PIPA590885 - Each of 1

₹ 45,047.34

In Stock

Quantity

1

Base Price: ₹ 45,047.34

GST (18%): ₹ 8,108.521

Total Price: ₹ 53,155.861

Antigen

Di-Methyl-DNMT3A (Lys44)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNMT3A

Gene Alias

AU015806, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA (cytosine-5)-methyltransferase 3A, DNA cytosine methyltransferase 3A2, DNA methyltransferase 3 alpha, DNA methyltransferase 3A, DNA methyltransferase HsaIIIA, DNA methyltransferase MmuIIIA, DNA MTase HsaIIIA, DNA MTase MmuIIIA, Dnmt3a, DNMT3A2, M.HsaIIIA, MmuIIIA, TBRS, W91664

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13435, 1788, 444984

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.6 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O88508, Q1LZ53, Q9Y6K1

Gene Symbols

DNMT3A

Immunogen

A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_0318981)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: ARKVG Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development
  • Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer
  • To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3
  • Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality
  • Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation
  • The Dnmt3 family members, Dnmt3a and Dnmt3b, are strongly expressed in ES cells but their expression is down regulated in differentiating ES cells and is low in adult somatic tissue
  • Recently, it has been shown that naturally occurring mutations of Dnmt3b gene occurs in patients with a rare autosomal recessive disorder, termed ICF (immunodeficiency, centromeric instability, and facial anomalies) syndrome.

Compare Similar Items

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Img

Thermo Scientific

PIPA590885

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Antigen:
Di-Methyl-DNMT3A (Lys44)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNMT3A

Gene Alias:
AU015806, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA (cytosine-5)-methyltransferase 3A, DNA cytosine methyltransferase 3A2, DNA methyltransferase 3 alpha, DNA methyltransferase 3A, DNA methyltransferase HsaIIIA, DNA methyltransferase MmuIIIA, DNA MTase HsaIIIA, DNA MTase MmuIIIA, Dnmt3a, DNMT3A2, M.HsaIIIA, MmuIIIA, TBRS, W91664

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13435, 1788, 444984

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.6 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O88508, Q1LZ53, Q9Y6K1

Gene Symbols:
DNMT3A

Immunogen:
A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_0318981)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA590886

--


Antigen:
GABRB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gabrb1

Gene Alias:
AW061132, B230208N19Rik, GABA beta subunit, GABA(A) receptor, GABA(A) receptor subunit beta-1, GABA(A) receptor, beta 1, GABA(A)R beta-1, GABA-RB, Gabrb1, Gabrb-1, gamma-aminobutyric acid, gamma-aminobutyric acid (GABA) A receptor, beta 1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1, gamma-aminobutyric acid A receptor beta 1, Gamma-aminobutyric acid receptor beta 1, gamma-aminobutyric acid receptor subunit beta-1, gamma-aminobutyric acid receptor, subunit beta 1, gamma-aminobutyric acid type A receptor beta1 subunit, gamma-aminobutyric acid type A receptor subunit beta1, GARB1, GBRB1, si:dkey-20i10.4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14400, 25450, 2560

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.11 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P15431, P18505, P50571

Gene Symbols:
Gabrb1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human GABA A Receptor beta 1 (GABRB1) (NP_0008032)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA590894

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Antigen:
CACNB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cacnb2

Gene Alias:
AW060387, brain calcium channel beta-subunit CaB2c (splice variant of the gene CaB2), CAB1, CAB2, Cacnb2, CACNLB1, Cacnlb2, Calcium channel voltage-dependent subunit beta 2, calcium channel, voltage-dependent, beta 2 subunit, calcium voltage-gated channel auxiliary subunit beta 2, cardiac calcium channel beta subunit, cardiac calcium channel beta-subunit CaB2a (splice variant of the gene CaB2, cardiac calcium channel beta-subunit CaB2b (splice variant of the gene CaB2), CAVB2, Cavbeta2, Cchb2, CCHLB1, lambert-Eaton myasthenic syndrome antigen B, L-type calcium channel beta subunit, L-type voltage-dependent calcium channel beta-2 subunit, MGC138502, MGC138504, MGC41896, myasthenic (Lambert-Eaton) syndrome antigen B, MYSB, voltage-dependent calcium channel beta2A subunit, voltage-dependent calcium channel beta2B subunit, voltage-dependent L-type calcium channel subunit beta-2, voltage-gated calcium channel beta2 subunit transcript variant X13

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116600, 12296, 783

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.64 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q08289, Q8CC27, Q8VGC3

Gene Symbols:
Cacnb2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 481-660 of human CACNB2 (NP_9638902)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA590896

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Antigen:
CD80

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD80

Gene Alias:
Activation B7-1 antigen, B7, B7 protein, B7.1, B71, B7-1, B7-1 protein, B7-1 protein precursor, BB1, B-lymphocyte activation antigen B7, Cd28l, CD28LG, CD28LG1, CD80, Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1), CD80 anitgen, CD80 antigen, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), Cd80 molecule, CD80 protein precursor, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, LAB7, Ly53, Ly-53, MIC17, sCD 80, sCD80, secreted B7-1 protein precursor, soluble CD 80, soluble CD80, T-cell costimulatory molecule, T-cell co-stimulatory protein B7-1, T-lymphocyte activation antigen CD80, TS/A-1, TSA1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12519, 25408, 941

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.58 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P33681, Q00609

Gene Symbols:
CD80

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD80 (NP_0051821)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG