PIPA591956
NLK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA591956-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA591956 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
NLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375, LAK1, nemo like kinase, nemo-like kinase, NLK, Protein LAK1, RGD1561602, serine/threonine protein kinase NLK, serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18099, 497961, 51701
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.12 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
D3ZSZ3, O54949, Q9UBE8
Gene Symbols
NLK
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 278-527 of human NLK (NP_0573153)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LKICDFGLAR VEELDESRHM TQEVVTQYYR APEILMGSRH YSNAIDIWSV GCIFAELLGR RILFQAQSPI QQLDLITDLL GTPSLEAMRT ACEGAKAHIL RGPHKQPSLP VLYTLSSQAT HEAVHLLCRM LVFDPSKRIS AKDALAHPYL DEGRLRYHTC MCKCCFSTST GRVYTSDFEP VTNPKFDDTF EKNLSSVRQV KEIIHQFILE QQKGNRVPLC INPQSAAFKS FISSTVAQPS EMPPSPLVWE; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cytoplasm, Nucleus NLK is a serine/threonine kinase involved in signal transduction and cellular communication
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors.
Compare Similar Items
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Antigen: NLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375, LAK1, nemo like kinase, nemo-like kinase, NLK, Protein LAK1, RGD1561602, serine/threonine protein kinase NLK, serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18099, 497961, 51701
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.12 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: D3ZSZ3, O54949, Q9UBE8
Gene Symbols: NLK
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 278-527 of human NLK (NP_0573153)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375, LAK1, nemo like kinase, nemo-like kinase, NLK, Protein LAK1, RGD1561602, serine/threonine protein kinase NLK, serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18099, 497961, 51701
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.12 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
D3ZSZ3, O54949, Q9UBE8
Gene Symbols:
NLK
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 278-527 of human NLK (NP_0573153)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FBXO32
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FBXO32
Gene Alias: 4833442G10Rik, AI430017, atrogin 1, atrogin1, atrogin-1, atrophy gene 1, F-box only protein 32, F-box protein 32, Fbx32, fbxo25, FBXO32, FLJ32424, Gm20361, MAFbx, MGC108443, MGC137646, MGC33610, Muscle atrophy F-box protein, similar to F-box only protein 32 isoform 1, zgc:56479
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114907, 67731
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.27 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q969P5, Q9CPU7
Gene Symbols: FBXO32
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBOX32 (NP_4781361)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
FBXO32
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FBXO32
Gene Alias:
4833442G10Rik, AI430017, atrogin 1, atrogin1, atrogin-1, atrophy gene 1, F-box only protein 32, F-box protein 32, Fbx32, fbxo25, FBXO32, FLJ32424, Gm20361, MAFbx, MGC108443, MGC137646, MGC33610, Muscle atrophy F-box protein, similar to F-box only protein 32 isoform 1, zgc:56479
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114907, 67731
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.27 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q969P5, Q9CPU7
Gene Symbols:
FBXO32
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBOX32 (NP_4781361)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RBM17
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rbm17
Gene Alias: 2700027J02Rik, 45 kDa-splicing factor, Rbm17, RNA binding motif protein 17, RNA-binding motif protein 17, Spf45, Splicing factor 45, splicing factor 45kDa
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 291295, 76938, 84991
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.35 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q8JZX4, Q96I25
Gene Symbols: Rbm17
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RBM17 (NP_1162941)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RBM17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rbm17
Gene Alias:
2700027J02Rik, 45 kDa-splicing factor, Rbm17, RNA binding motif protein 17, RNA-binding motif protein 17, Spf45, Splicing factor 45, splicing factor 45kDa
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
291295, 76938, 84991
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q8JZX4, Q96I25
Gene Symbols:
Rbm17
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RBM17 (NP_1162941)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CtBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CTBP1
Gene Alias: 50 kDa BFA-dependent ADP-ribosylation substrate, 50-kDa BFA-induced ADP-ribosylated substrate, 50-kDaBFA-inducedADP-ribosylatedsubstrate, BARS, BARS-50, brefeldin A-ADP-riboslyated substrate, brefeldin A-ribosylated substrate, CTBP, CtBP1, CtBP1-L, CtBP1-S, CtBP3, CtBP3/BARS, C-terminal binding protein 1, C-terminal-binding protein 1, C-terminal-binding protein 3, C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate, D4S115h, D5H4S115, D5H4S115E, MGC104684
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1487
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.06 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q13363
Gene Symbols: CTBP1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human CtBP1 (NP_0013191)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CtBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CTBP1
Gene Alias:
50 kDa BFA-dependent ADP-ribosylation substrate, 50-kDa BFA-induced ADP-ribosylated substrate, 50-kDaBFA-inducedADP-ribosylatedsubstrate, BARS, BARS-50, brefeldin A-ADP-riboslyated substrate, brefeldin A-ribosylated substrate, CTBP, CtBP1, CtBP1-L, CtBP1-S, CtBP3, CtBP3/BARS, C-terminal binding protein 1, C-terminal-binding protein 1, C-terminal-binding protein 3, C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate, D4S115h, D5H4S115, D5H4S115E, MGC104684
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1487
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.06 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q13363
Gene Symbols:
CTBP1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human CtBP1 (NP_0013191)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG