PIPA592949
PTPRN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA592949-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA592949 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
PTPRN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPRN
Gene Alias
105 kDa islet cell antigen, BEM-3, brain-enriched membrane-associated protein tyrosine phosphatase, IA2, IA-2, IA-2/PTP, ICA 512, ICA105, ICA3, ICA512, ICA512-CCF, ICA512-cleaved cytosolic fragment, ICA512-N-terminal fragment, ICA512-NTF, ICA512-TMF, ICA512-transmembrane fragment, islet cell antigen 2, islet cell antigen 512, Islet cell autoantigen 3, mIA-A, mKIAA4064, protein tyrosine phosphatase, receptor type N, protein tyrosine phosphatase, receptor type, N, protein tyrosine phosphatase, receptor-type, N, protein tyrosine phosphatase-like N, PTP IA-2, PTPLP, Ptprn, receptor-type tyrosine-protein phosphatase-like N, R-PTP-N
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116660, 19275, 5798
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.77 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q16849, Q60673, Q63259
Gene Symbols
PTPRN
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_0011866931)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: STGHMILAYM EDHLRNRDRL AKEWQALCAY QAEPNTCATA QGEGNIKKNR HPDFLPYDHA RIKLKVESSP SRSDYINASP IIEHDPRMPA YIATQGPLSH TIADFWQMVW ESGCTVIVML TPLVEDGVKQ CDRYWPDEGA SLYHVYEVNL VSEHIWCEDF LVRSFYLKNV QTQETRTLTQ FHFLSWPAEG TPASTRPLLD FRRKVNKCYR GRSCPIIVHC SDGAGRTGTY ILIDMVLNRM AKGVKEIDIA ATLEHVRDQR PGLVRSKDQF EFALTAVAEE VNAILKALPQ; Positive Samples: 293T, NIH/3T3, Raji, Mouse brain, Rat brian; Cellular Location: Cell junction, Cell membrane, Cell projection, Cytoplasmic vesicle, Endosome, Membrane, Perikaryon, Single-pass type I membrane protein, axon, secretory vesicle membrane, synapse IA-2 (insulinoma-associated protein 2, ICA512, PTPRN) is a member of the transmembrane protein tyrosine phosphatase (PTP) family located in secretory granules of neuroendocrine cells
- The IA-2 protein is 979 amino acids in length and consists of a luminal domain, transmembrane domain, and cytoplasmic domain
- Although a member of the PTP family, IA-2 lacks phosphatase activity with known substrates due to amino acid substitutions at critical sites in its PTP domain
- Two paralog RPTPs, IA-2 and IA-2beta were identified as major autoantigens in type-1 diabetes mellitus
- On granule exocytosis, the IA-2 cytoplasmic domain is cleaved and the resulting cytosolic fragment moves into the nucleus where it enhances the levels of phosphorylated STAT5 and STAT3, thereby inducing insulin gene transcription and granule biogenesis
- IA-2 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
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Antigen: PTPRN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRN
Gene Alias: 105 kDa islet cell antigen, BEM-3, brain-enriched membrane-associated protein tyrosine phosphatase, IA2, IA-2, IA-2/PTP, ICA 512, ICA105, ICA3, ICA512, ICA512-CCF, ICA512-cleaved cytosolic fragment, ICA512-N-terminal fragment, ICA512-NTF, ICA512-TMF, ICA512-transmembrane fragment, islet cell antigen 2, islet cell antigen 512, Islet cell autoantigen 3, mIA-A, mKIAA4064, protein tyrosine phosphatase, receptor type N, protein tyrosine phosphatase, receptor type, N, protein tyrosine phosphatase, receptor-type, N, protein tyrosine phosphatase-like N, PTP IA-2, PTPLP, Ptprn, receptor-type tyrosine-protein phosphatase-like N, R-PTP-N
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116660, 19275, 5798
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.77 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q16849, Q60673, Q63259
Gene Symbols: PTPRN
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_0011866931)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTPRN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRN
Gene Alias:
105 kDa islet cell antigen, BEM-3, brain-enriched membrane-associated protein tyrosine phosphatase, IA2, IA-2, IA-2/PTP, ICA 512, ICA105, ICA3, ICA512, ICA512-CCF, ICA512-cleaved cytosolic fragment, ICA512-N-terminal fragment, ICA512-NTF, ICA512-TMF, ICA512-transmembrane fragment, islet cell antigen 2, islet cell antigen 512, Islet cell autoantigen 3, mIA-A, mKIAA4064, protein tyrosine phosphatase, receptor type N, protein tyrosine phosphatase, receptor type, N, protein tyrosine phosphatase, receptor-type, N, protein tyrosine phosphatase-like N, PTP IA-2, PTPLP, Ptprn, receptor-type tyrosine-protein phosphatase-like N, R-PTP-N
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116660, 19275, 5798
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.77 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q16849, Q60673, Q63259
Gene Symbols:
PTPRN
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_0011866931)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GPBB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PYGB
Gene Alias: brain glycogen phosphorylase, glycogen phosphorylase B, glycogen phosphorylase, brain form, GLYPHOA, GPBB, MGC9213, phosphorylase, glycogen, brain, PYGB
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110078, 25739, 5834
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P11216, P53534, Q8CI94
Gene Symbols: PYGB
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_0028532)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GPBB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PYGB
Gene Alias:
brain glycogen phosphorylase, glycogen phosphorylase B, glycogen phosphorylase, brain form, GLYPHOA, GPBB, MGC9213, phosphorylase, glycogen, brain, PYGB
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110078, 25739, 5834
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P11216, P53534, Q8CI94
Gene Symbols:
PYGB
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_0028532)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RBP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBP3
Gene Alias: D10S64, D10S65, D10S66, interphotoreceptor retinoid binding protein, interphotoreceptor retinoid-binding protein, interphotoreceptor retinol- binding protein, interstitial retinol binding protein 3, interstitial retinol-binding protein, interstitial retinol-binding protein 3, IRBP, RBP3, Rbp-3, RBPI, retinol binding protein 3, retinol binding protein 3, interstitial, retinol-binding protein 3, RP66
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19661, 24711, 5949
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.97 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P10745, P49194
Gene Symbols: RBP3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-320 of human RBP3 (NP_0028911)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RBP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBP3
Gene Alias:
D10S64, D10S65, D10S66, interphotoreceptor retinoid binding protein, interphotoreceptor retinoid-binding protein, interphotoreceptor retinol- binding protein, interstitial retinol binding protein 3, interstitial retinol-binding protein, interstitial retinol-binding protein 3, IRBP, RBP3, Rbp-3, RBPI, retinol binding protein 3, retinol binding protein 3, interstitial, retinol-binding protein 3, RP66
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19661, 24711, 5949
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.97 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P10745, P49194
Gene Symbols:
RBP3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-320 of human RBP3 (NP_0028911)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SF1
Gene Alias: BBP, D11S636, M ZFM1, Mammalian branch point-binding protein, MBBP, MZFM, SF, SF1, Splicing factor 1, transcription factor ZFM1, WBP4, wu:fc09f06, ZCCHC25, ZFM1, Zfp162, Zinc finger gene in MEN1 locus, zinc finger protein 162, ZNF162
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22668, 7536
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.06 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q15637, Q64213
Gene Symbols: SF1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SF1 (NP_9737271)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SF1
Gene Alias:
BBP, D11S636, M ZFM1, Mammalian branch point-binding protein, MBBP, MZFM, SF, SF1, Splicing factor 1, transcription factor ZFM1, WBP4, wu:fc09f06, ZCCHC25, ZFM1, Zfp162, Zinc finger gene in MEN1 locus, zinc finger protein 162, ZNF162
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22668, 7536
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.06 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q15637, Q64213
Gene Symbols:
SF1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SF1 (NP_9737271)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG