PIPA592981
IL18BP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA592981-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA592981 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
IL18BP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IL18BP
Gene Alias
Igifbp, Il18bp, IL-18BP, IL18BPa, interferon gamma inducing factor binding protein, interferon gamma-inducing factor-binding protein, interleukin 18 binding protein, interleukin-18 binding protein, interleukin-18-binding protein, MC51L-53L-54L homolog gene product, MC54L, Tadekinig-alfa
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10068, 16068
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.04 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O95998, Q9Z0M9
Gene Symbols
IL18BP
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_0011385291)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TPVSQTTTAA TASVRSTKDP CPSQPPVFPA AKQCPALEVT WPEVEVPLNG TLSLSCVACS RFPNFSILYW LGNGSFIEHL PGRLWEGSTS RERGSTGTQL CKALVLEQLT PALHSTNFSC VLVDPEQVVQ RHVVLAQLWA GLRATLPPTQ EALPSSHSSP QQQG; Positive Samples: U-937, Mouse thymus Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
- Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
- As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
- The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
- Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
- As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.
Compare Similar Items
Show Difference
Antigen: IL18BP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL18BP
Gene Alias: Igifbp, Il18bp, IL-18BP, IL18BPa, interferon gamma inducing factor binding protein, interferon gamma-inducing factor-binding protein, interleukin 18 binding protein, interleukin-18 binding protein, interleukin-18-binding protein, MC51L-53L-54L homolog gene product, MC54L, Tadekinig-alfa
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10068, 16068
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.04 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O95998, Q9Z0M9
Gene Symbols: IL18BP
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_0011385291)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
IL18BP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL18BP
Gene Alias:
Igifbp, Il18bp, IL-18BP, IL18BPa, interferon gamma inducing factor binding protein, interferon gamma-inducing factor-binding protein, interleukin 18 binding protein, interleukin-18 binding protein, interleukin-18-binding protein, MC51L-53L-54L homolog gene product, MC54L, Tadekinig-alfa
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10068, 16068
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.04 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O95998, Q9Z0M9
Gene Symbols:
IL18BP
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_0011385291)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: DHRS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DHRS2
Gene Alias: 5430405K24Rik, dehydrogenase/reductase (SDR family) member 2, dehydrogenase/reductase 2, dehydrogenase/reductase member 2, dehydrogenase/reductase SDR family member 2, mitochondrial, Dhrs2, Dicarbonyl reductase HEP27, Hep27, Protein D, SDR family member, SDR25C1, Short chain dehydrogenase/reductase family 25C member 1, short chain dehydrogenase/reductase family 25C, member 1, short-chain alcohol dehydrogenase family member
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10202, 691464, 71412
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.12 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q13268
Gene Symbols: DHRS2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DHRS2 (NP_8789121)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DHRS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DHRS2
Gene Alias:
5430405K24Rik, dehydrogenase/reductase (SDR family) member 2, dehydrogenase/reductase 2, dehydrogenase/reductase member 2, dehydrogenase/reductase SDR family member 2, mitochondrial, Dhrs2, Dicarbonyl reductase HEP27, Hep27, Protein D, SDR family member, SDR25C1, Short chain dehydrogenase/reductase family 25C member 1, short chain dehydrogenase/reductase family 25C, member 1, short-chain alcohol dehydrogenase family member
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10202, 691464, 71412
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.12 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q13268
Gene Symbols:
DHRS2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DHRS2 (NP_8789121)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NCS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ncs1
Gene Alias: 9430075O15Rik, A730032G13Rik, AI836659, FLUP, Freq, frequenin, Frequenin homolog, frequenin-like protein, Frequenin-like ubiquitous protein, Mfreq, Ncs1, NCS-1, Neuronal calcium sensor 1, neuronal calcium sensor-1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14299, 23413, 65153
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.98 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P62166, P62168, Q8BNY6
Gene Symbols: Ncs1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NCS1 (NP_0551012)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NCS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ncs1
Gene Alias:
9430075O15Rik, A730032G13Rik, AI836659, FLUP, Freq, frequenin, Frequenin homolog, frequenin-like protein, Frequenin-like ubiquitous protein, Mfreq, Ncs1, NCS-1, Neuronal calcium sensor 1, neuronal calcium sensor-1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14299, 23413, 65153
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P62166, P62168, Q8BNY6
Gene Symbols:
Ncs1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NCS1 (NP_0551012)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Nucleostemin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GNL3
Gene Alias: C77032, E2IG3, E2-induced gene 3 protein, estradiol-induced nucleotide binding protein, G protein nucleolar 3, Gnl3, guanine nucleotide binding protein-like 3 (nucleolar), guanine nucleotide-binding protein-like 3, MGC800, NNP47, novel nucleolar protein 47, Ns, nucleolar GTP-binding protein 3, Nucleostemin
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26354
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9BVP2
Gene Symbols: GNL3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GNL3 (NP_9965621)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Nucleostemin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GNL3
Gene Alias:
C77032, E2IG3, E2-induced gene 3 protein, estradiol-induced nucleotide binding protein, G protein nucleolar 3, Gnl3, guanine nucleotide binding protein-like 3 (nucleolar), guanine nucleotide-binding protein-like 3, MGC800, NNP47, novel nucleolar protein 47, Ns, nucleolar GTP-binding protein 3, Nucleostemin
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26354
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9BVP2
Gene Symbols:
GNL3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GNL3 (NP_9965621)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG