PIPA593099

HAS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA593099-Each-of-1 In Stock ₹ 44,277.30

PIPA593099 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

HAS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HAS3

Gene Alias

HA synthase 3, Has3, Hyaluronan synthase 3, hyaluronate synthase 3, Hyaluronic acid synthase 3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15118, 266805, 3038

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.45 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O00219, O08650

Gene Symbols

HAS3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 67-281 of human HAS3 (NP_6195151)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: HRRMRRAGQA LKLPSPRRGS VALCIAAYQE DPDYLRKCLR SAQRISFPDL KVVMVVDGNR QEDAYMLDIF HEVLGGTEQA GFFVWRSNFH EAGEGETEAS LQEGMDRVRD VVRASTFSCI MQKWGGKREV MYTAFKALGD SVDYIQVCDS DTVLDPACTI EMLRVLEEDP QVGGVGGDVQ PPGKGMAVED DQVQAAQVRA TEAWSVHQRH VSREQ; Positive Samples: A-549, HL-60, SKOV3, SW480, Mouse heart, Rat liver, Rat heart; Cellular Location: Membrane, Multi-pass membrane protein HAS1, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins
  • The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1,3 and b-1,4 glycosidic bonds
  • The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix
  • Both HAS1 and HAS2 synthesize high molecular-weight HA, whereas HAS3 produces lower molecular weight HA
  • The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins
  • HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults
  • HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis
  • Specifically, IFN-g markedly upregulates HAS3 mRNA, whereas TGFbeta downregulates HAS3 transcript levels
  • The human HAS3 gene maps to chromosome 16q22
  • 1.

Compare Similar Items

Show Difference

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PIPA593099

--


Antigen:
HAS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HAS3

Gene Alias:
HA synthase 3, Has3, Hyaluronan synthase 3, hyaluronate synthase 3, Hyaluronic acid synthase 3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15118, 266805, 3038

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O00219, O08650

Gene Symbols:
HAS3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 67-281 of human HAS3 (NP_6195151)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA593101

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Antigen:
HOXB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hoxb1

Gene Alias:
HCFP3, homeo box B1, homeobox B1, homeobox protein Hox-2.9, Homeobox protein Hox-2I, homeobox protein Hox-B1, HOX2, Hox-2.9, Hox-29, HOX2I, Hoxb1, Hoxb-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15407, 303491, 3211

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P14653, P17919

Gene Symbols:
Hoxb1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human HOXB1 (NP_0021352)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA593104

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Antigen:
HYAL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HYAL1

Gene Alias:
Hya1, HYAL1, Hyal-1, Hyaluronidase, hyaluronidase 1, hyaluronidase-1, hyaluronoglucosaminidase 1, hyaluronoglucosaminidase-1, LUCA1, LuCa-1, Lung carcinoma protein 1, MPS9, NAT6, plasma hyaluronidase, tumor suppressor LUCA-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15586, 3373, 367166

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q12794, Q76HN1, Q91ZJ9

Gene Symbols:
HYAL1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 136-435 of human HYAL1 (NP_1493492)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA593108

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Antigen:
IL11RA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL11RA

Gene Alias:
AI314697, CRSDA, Enhancer trap locus homolog 2, Etl2, etl-2, GP130, IL-11 receptor subunit alpha, IL-11 receptor subunit alpha-1, IL-11R subunit alpha, IL-11R subunit alpha-1, Il11ra, IL-11RA, Il11ra1, IL-11RA1, Il11ra2, Il-11ra-alpha, IL-11R-alpha, IL-11R-alpha-1, interleukin 11 receptor subunit alpha, interleukin 11 receptor, alpha, interleukin 11 receptor, alpha chain 1, interleukin 11 receptor, alpha chain 2, interleukin-11 receptor alpha chain, interleukin-11 receptor subunit alpha, Interleukin-11 receptor subunit alpha-1, locus 2, novel cytokine receptor 1, NR1, NR-1, sIL11RA

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16157, 245983, 3590

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.89 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q14626, Q64385, Q99MF4

Gene Symbols:
IL11RA, Il11ra1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human IL11RA (NP_0011362561)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG