PIPA595234
tPA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595234-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA595234 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
tPA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PLAT
Gene Alias
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5327
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Western Blot
Concentration
500 μg/mL
Formulation
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.
P00750
Gene Symbols
PLAT
Immunogen
E.coli-derived human TPA recombinant protein (Position: H366-P562).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human TPA shares 83% and 84% amino acid (aa) sequence identity with mouse and rat TPA, respectively
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- TPA converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen
- By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physio pathological events
- It specifically cleaves the Arg- -Val bond in plasminogen to form plasmin, and is comprised of a heterodimer of chain A and chain B held by a disulfide bond
- TPA binds to fibrin with high affinity
- This interaction leads to an increase in the catalytic efficiency of the enzyme between 100-and 1000-fold, due to an increase in affinity for plasminogen
- Similarly, binding to heparin increases the activation of plasminogen
- Binding to laminin and fibronectin has also been demonstrated
- TPA also binds to mannose receptor and the low-density lipoprotein receptor-related protein (LRP1)
- These proteins are involved in TPA clearance
- TPA binds to annexin II and to cytokeratin 8
- As yet unidentified interactions on endothelial cells and vascular smooth muscle cells (VSMC) lead to a 100-fold stimulation of plasminogen activation
- In addition, binding to VSMC reduces TPA inhibition by PAI-1 by 30-fold.
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Antigen: tPA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLAT
Gene Alias: 3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5327
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P00750
Gene Symbols: PLAT
Immunogen: E.coli-derived human TPA recombinant protein (Position: H366-P562).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
tPA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLAT
Gene Alias:
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5327
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P00750
Gene Symbols:
PLAT
Immunogen:
E.coli-derived human TPA recombinant protein (Position: H366-P562).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PP2A alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP2CA
Gene Alias: B55-GAMMA, hypothetical protein, IMYPNO, IMYPNO1, Methyl-PPP2CA, MGC33570, PP2A, PP2A alpha, PP2A C terminal, PP2A L9, PP2A Leucine 9, Pp2a1, PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, Ppp2ca, PR52, PR55G, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, protein phosphatase 2 catalytic subunit alpha, protein phosphatase 2, catalytic subunit, alpha isoform, protein phosphatase 2, catalytic subunit, alpha isozyme, protein phosphatase 2,catalytic subunit alpha isozyme, protein phosphatase 2A alpha subunit, protein phosphatase 2A catalytic subunit alpha isoform, protein phosphatase 2a, catalytic subunit, alpha isoform, protein phosphatase type 2A catalytic subunit, protein phosphatase-2A, protein phosphatase-2A-alpha, R75353, replication protein C, RP-C, serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, unnamed protein product
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19052, 24672, 5515
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P63330, P63331, P67775
Gene Symbols: PPP2CA
Immunogen: E.coli-derived human PP2A-alpha recombinant protein (Position: M1-L309).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PP2A alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP2CA
Gene Alias:
B55-GAMMA, hypothetical protein, IMYPNO, IMYPNO1, Methyl-PPP2CA, MGC33570, PP2A, PP2A alpha, PP2A C terminal, PP2A L9, PP2A Leucine 9, Pp2a1, PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, Ppp2ca, PR52, PR55G, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, protein phosphatase 2 catalytic subunit alpha, protein phosphatase 2, catalytic subunit, alpha isoform, protein phosphatase 2, catalytic subunit, alpha isozyme, protein phosphatase 2,catalytic subunit alpha isozyme, protein phosphatase 2A alpha subunit, protein phosphatase 2A catalytic subunit alpha isoform, protein phosphatase 2a, catalytic subunit, alpha isoform, protein phosphatase type 2A catalytic subunit, protein phosphatase-2A, protein phosphatase-2A-alpha, R75353, replication protein C, RP-C, serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19052, 24672, 5515
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P63330, P63331, P67775
Gene Symbols:
PPP2CA
Immunogen:
E.coli-derived human PP2A-alpha recombinant protein (Position: M1-L309).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PRDX6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRDX6
Gene Alias: 1-Cys, 1-Cys peroxiredoxin, 1-Cys PRX, 1-cysPrx, 24 kDa protein, 9430088D19Rik, AA690119, Acidic calcium-independent phospholipase A2, aiPLA2, Antioxidant protein 2, Aop2, Brp-12, CP-3, epididymis secretory sperm binding protein Li 128m, GPx, HEL-S-128m, KIAA0106, Liver 2D page spot 40, Ltw4, Ltw-4, Lvtw-4, MGC46173, MSP23, NKEFA, Non-selenium glutathione peroxidase, NSGPx, ORF06, p29, PAG, PAGA, PAGB, peroxiredoxin 6, peroxiredoxin-6, Prdx5, Prdx6, PRX, Prx6, Red blood cells page spot 12, thiol-specific antioxidant protein, Tsa
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11758, 94167, 9588
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: O08709, O35244, P30041
Gene Symbols: PRDX6
Immunogen: E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PRDX6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRDX6
Gene Alias:
1-Cys, 1-Cys peroxiredoxin, 1-Cys PRX, 1-cysPrx, 24 kDa protein, 9430088D19Rik, AA690119, Acidic calcium-independent phospholipase A2, aiPLA2, Antioxidant protein 2, Aop2, Brp-12, CP-3, epididymis secretory sperm binding protein Li 128m, GPx, HEL-S-128m, KIAA0106, Liver 2D page spot 40, Ltw4, Ltw-4, Lvtw-4, MGC46173, MSP23, NKEFA, Non-selenium glutathione peroxidase, NSGPx, ORF06, p29, PAG, PAGA, PAGB, peroxiredoxin 6, peroxiredoxin-6, Prdx5, Prdx6, PRX, Prx6, Red blood cells page spot 12, thiol-specific antioxidant protein, Tsa
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11758, 94167, 9588
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
O08709, O35244, P30041
Gene Symbols:
PRDX6
Immunogen:
E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PSCA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSCA
Gene Alias: 2210408B04Rik, caldesmon, CDM, HCAD, H-CAD, LCAD, L-CAD, NAG22, PRO232, prostate stem cell antigen, PSCA, UNQ206, UNQ206/PRO232
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 680210, 72373, 8000
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: O43653, P57096
Gene Symbols: PSCA
Immunogen: E.coli-derived human PSCA recombinant protein (Position: L21-S95).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PSCA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSCA
Gene Alias:
2210408B04Rik, caldesmon, CDM, HCAD, H-CAD, LCAD, L-CAD, NAG22, PRO232, prostate stem cell antigen, PSCA, UNQ206, UNQ206/PRO232
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
680210, 72373, 8000
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
O43653, P57096
Gene Symbols:
PSCA
Immunogen:
E.coli-derived human PSCA recombinant protein (Position: L21-S95).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG