PIPA595315

Arg3.1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595315-Each-of-1 In Stock ₹ 44,191.74

PIPA595315 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

Arg3.1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Arc

Gene Alias

activity regulated cytoskeletal-associated protein, activity regulated cytoskeleton associated protein, activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein, activity-regulated gene 3.1 protein homolog, Arc, arc {ECO:0000312, ARC/ARG3.1, Arc3.1, arg3.1, Arg3.1/ARC, C86064, Growth factor ARC, hArc, KIAA0278, mArc, rg3.1, RGD:62037}

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11838, 23237, 54323

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunocytochemistry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

Q63053, Q7LC44, Q9WV31

Gene Symbols

Arc

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Arc (332-366aa KLKRFLRHPLPKTLEQLIQRGMEVQDDLEQAAEPA).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer in the nervous system
  • ARC protein is released from neurons in extracellular vesicles that mediate the transfer of ARC mRNA into new target cells, where ARC mRNA can undergo activity-dependent translation
  • ARC capsids are endocytosed and are able to transfer ARC mRNA into the cytoplasm of neurons
  • Acts as a key regulator of synaptic plasticity: required for protein synthesis-dependent forms of long-term potentiation (LTP) and depression (LTD) and for the formation of long-term memory
  • Regulates synaptic plasticity by promoting endocytosis of AMPA receptors (AMPARs) in response to synaptic activity: this endocytic pathway maintains levels of surface AMPARs in response to chronic changes in neuronal activity through synaptic scaling, thereby contributing to neuronal homeostasis
  • Acts as a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum by mediating elimination of surplus climbing fiber synapses
  • Accumulates at weaker synapses, probably to prevent their undesired enhancement
  • This suggests that ARC-containing virion-like capsids may be required to eliminate synaptic material
  • Required to transduce experience into long-lasting changes in visual cortex plasticity and for long-term memory
  • Involved in postsynaptic trafficking and processing of amyloid-beta A4 (APP) via interaction with PSEN1
  • In addition to its role in synapses, also involved in the regulation of the immune system: specifically expressed in skin-migratory dendritic cells and regulates fast dendritic cell migration, thereby regulating T-cell activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595315

--


Antigen:
Arg3.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Arc

Gene Alias:
activity regulated cytoskeletal-associated protein, activity regulated cytoskeleton associated protein, activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein, activity-regulated gene 3.1 protein homolog, Arc, arc {ECO:0000312, ARC/ARG3.1, Arc3.1, arg3.1, Arg3.1/ARC, C86064, Growth factor ARC, hArc, KIAA0278, mArc, rg3.1, RGD:62037}

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11838, 23237, 54323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q63053, Q7LC44, Q9WV31

Gene Symbols:
Arc

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Arc (332-366aa KLKRFLRHPLPKTLEQLIQRGMEVQDDLEQAAEPA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595316

--


Antigen:
Cdc25C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdc25c

Gene Alias:
CDC25, CDC25C, Cdc25m1, cell division cycle 25C, dual specificity phosphatase CDC25C, EC 3.1.3.48, mitosis inducer CDC25, M-phase inducer phosphatase 3, MPIP3, OTTHUMP00000159490, OTTHUMP00000224012, OTTHUMP00000224013, OTTHUMP00000224016, phosphotyrosine phosphatase, PPP1R60, protein phosphatase 1, regulatory subunit 60

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
307511, 995

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P30307

Gene Symbols:
Cdc25c

Immunogen:
E.coli-derived human Cdc25C recombinant protein (Position: K175-P473).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595318

--


Antigen:
FMO2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fmo2

Gene Alias:
2310008D08Rik, 2310042I22Rik, AW107733, Dimethylaniline monooxygenase [N-oxide-forming] 2, dimethylaniline oxidase 2, flavin containing dimethylaniline monoxygenase 2, flavin containing monooxygenase 2, flavin containing monooxygenase 2 (non-functional), FMO 1B1, FMO 2, FMO, pulmonary, FMO1B1, FMO2, Pulmonary flavin-containing monooxygenase 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2327

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q99518

Gene Symbols:
Fmo2

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human FMO2 (78-115aa FPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595319

--


Antigen:
OGT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OGT

Gene Alias:
1110038P24Rik, 4831420N21Rik, AI115525, FLJ23071, HINCUT-1, HRNT1, MGC22921, O linked N-acetylglucosamine transferase, O-GLCNAC, o-glcnac transferase, O-GlcNAc transferase p110 subunit, O-GlcNAc transferase subunit p110, OGT, Ogtl, O-linked N-acetylglucosamine (GlcNAc) transferase, O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase), O-linked N-acetylglucosamine transferase, O-linked N-acetylglucosamine transferase 110 kDa subunit, UDP-N-acetylglucosamine:polypeptide-N- acetylglucosaminyl transferase, UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108155, 26295, 8473

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
O15294, P56558, Q8CGY8

Gene Symbols:
OGT

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human OGT (1008-1046aa NTKQYTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG