PIPA595412

BRCA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595412-Each-of-1 In Stock ₹ 44,705.10

PIPA595412 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BRCA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BRCA1

Gene Alias

brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

672

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

P38398

Gene Symbols

BRCA1

Immunogen

E.coli-derived human BRCA1 recombinant protein (Position: T1681-E1781).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Human BRCA1 shares 73.3% and 74.3% amino acid (aa) sequence identity with mouse and rat BRCA1, respectively
  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor in combination with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC (for BRCA1 associated genome surveillance complex)
  • BRCA1 associates with RNA polymerase II, and through the C terminal domain, also interacts with histone deacetylase complex
  • The BRCA1 protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595412

--


Antigen:
BRCA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
E.coli-derived human BRCA1 recombinant protein (Position: T1681-E1781).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA595414

--


Antigen:
DEFA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DEFA1

Gene Alias:
alpha-defensin 1, Cryptdin-1, DEF1, Defa1, DEFA1B, DEFA2, Defcr, Defcr1, defensin alpha 1, defensin related cryptdin peptide 1, defensin, alpha 1, defensin, alpha 1, myeloid-related sequence, defensin, alpha 2, defensin-1, defensin-related cryptdin peptide, HNP-1, HNP-2, HP 1-56, HP1, HP-1, HP-2, MRS, myeloid-related sequence, neutrophil defensin 1, Neutrophil defensin 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1667

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P59665

Gene Symbols:
DEFA1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Alpha Defensin 1 (65-94aa ACYCRIPACIAGERRYGTCIYQGRLWAFCC).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA595415

--


Antigen:
IL-13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il13

Gene Alias:
ALRH, ALRH antibody, BHR1, il 13, Il13, Il-13, IL-13, cytokine, ILN, Interleukin, interleukin 13, Interleukin13, interleukin-13, interleukin-13 precursor, L13, MGC116786, MGC116788, MGC116789, NC30, NC30 antibody, P600, P600 antibody, T-cell activation protein P600

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3596

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P35225

Gene Symbols:
Il13

Immunogen:
E.coli-derived human IL13 recombinant protein (Position: P36-N146).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA595416

--


Antigen:
Cytokeratin 18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT18

Gene Alias:
cb83, Cell proliferation-inducing gene 46 protein, CK 18, CK18, CK-18, CYK18, cytokeratin 18, cytokeratin endo B, cytokeratin type -1, DAPK-1, Cytokeratin18, cytokeratin-18, dapk1, dorsal aorta proneprin kinesin-1, DreK18, Endo B, I79_023185, K 18, K18, keratin 18, keratin 18, type I, keratin 18a, tandem duplicate 1, keratin complex 1, acidic, gene 18, keratin D, Keratin, type I cytoskeletal 18, Keratin18, keratin-18, Kerd, KRT 18, Krt1-18, KRT18, krt18 {ECO:0000250, krt18a.1, LOC100008885, PIG46, sb:cb83, type I cytoskeletal 18, UniProtKB:P05783}, wu:fa13f02, wu:fb36b04

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16668, 294853, 3875

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P05783, P05784, Q5BJY9

Gene Symbols:
KRT18

Immunogen:
E.coli-derived human Cytokeratin 18 recombinant protein (Position: E204-H430).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG