PIPA595459
IL-22 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595459-Each-of-1 | In Stock | ₹ 45,817.38 |
PIPA595459 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,817.38
GST (18%): ₹ 8,247.128
Total Price: ₹ 54,064.508
Antigen
IL-22
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IL22
Gene Alias
Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
500836, 50616, 50929
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
ELISA, Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
Q9GZX6, Q9JJY9
Gene Symbols
IL22
Immunogen
E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- IL-22 also known as IL-10-related T-cell derived inducible factor, is an alpha helical cytokine and is considered a member of the IFN-IL-10 family, which includes IL-19, IL-20, IL-24, IL-26, IL-28, IL-29, and the type I and II interferons
- IL-22 is produced mainly by activated T cells and NK cells
- In humans, the IL-22 gene is located on the q arm of chromosome 12, and is structurally related to IL10
- IL-22 acts by engaging the heterodimeric receptor complex consisting of primary receptor IL-22R1 and accessory receptor IL-10R2
- IL-22R1 also binds IL-20 and IL-24; IL-10R2 also binds IL-10, IL-27, IL-28, and IL-29
- Binding of IL-22 to its receptor complex induces signal transduction, particularly via the JAK-STAT pathway
- In addition to the membrane-bound IL-22R1/IL-10R2 complex, a soluble single-chain IL-22 receptor termed IL-22BP has been found to antagonize IL-22 binding and signaling
- IL-22 appears not to directly influence immune cells, and major targets of the cytokine appear to be nonimmune cells, such as cells of the skin, digestive and respiratory system, as well as hepatocytes, and keratinocytes
- IL-22 has been described as an effector cytokine of the Th17 lineage
- Along with IL-17A and IL-17F, IL-22 regulates genes associated with innate immunity of the skin
- IL-17A, IL-17F and IL-22 are all co-expressed by Th17 cells, however, they are differentially regulated
- The effects of IL-22 include induction of acute phase reactants and antimicrobial proteins, as well as increasing the mobility of keratinocytes
- IL-22 is highly expressed during chronic inflammation, and found to activate intracellular kinases and transcription factors
- IL-22 is critical for host defense against infections of extracellular pathogens, and promotes wound-healing responses
- IL-22 is upregulated in activated T cells
- IL-22 has been reported to mediate IL-23-induced acanthosis and dermal inflammation through activation of STAT3.
Compare Similar Items
Show Difference
Antigen: IL-22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL22
Gene Alias: Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 500836, 50616, 50929
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: ELISA, Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q9GZX6, Q9JJY9
Gene Symbols: IL22
Immunogen: E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL-22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL22
Gene Alias:
Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
500836, 50616, 50929
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
ELISA, Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q9GZX6, Q9JJY9
Gene Symbols:
IL22
Immunogen:
E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NOTCH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Notch1
Gene Alias: 9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18128, 4851
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P46531, Q01705
Gene Symbols: Notch1
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Notch1 (1797-1827aa LKNASDGALMDDNQNEWGDEDLETKKFRFEE).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NOTCH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Notch1
Gene Alias:
9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18128, 4851
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P46531, Q01705
Gene Symbols:
Notch1
Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Notch1 (1797-1827aa LKNASDGALMDDNQNEWGDEDLETKKFRFEE).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NPAS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Npas2
Gene Alias: Basic-helix-loop-helix-PAS protein MOP4, bHLHe9, Class E basic helix-loop-helix protein 9, member of PAS protein 4, member of PAS superfamily 4, MOP4, neuronal PAS domain protein 2, neuronal PAS domain-containing protein 2, Neuronal PAS2, NPAS2, PAS domain-containing protein 4, PASD4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18143, 316351, 4862
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P97460, Q99743
Gene Symbols: Npas2
Immunogen: E.coli-derived human NPAS2 recombinant protein (Position: D474-Q578).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NPAS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Npas2
Gene Alias:
Basic-helix-loop-helix-PAS protein MOP4, bHLHe9, Class E basic helix-loop-helix protein 9, member of PAS protein 4, member of PAS superfamily 4, MOP4, neuronal PAS domain protein 2, neuronal PAS domain-containing protein 2, Neuronal PAS2, NPAS2, PAS domain-containing protein 4, PASD4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18143, 316351, 4862
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P97460, Q99743
Gene Symbols:
Npas2
Immunogen:
E.coli-derived human NPAS2 recombinant protein (Position: D474-Q578).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: c-Raf
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Raf1
Gene Alias: 6430402F14Rik, AA990557, BB129353, CMD1NN, CRAF, C-RAF, C-Raf proto-oncogene, serine/threonine kinase, Craf1, Craf1 transforming, D830050J10Rik, EC 2.7.11.1, kinase Raf1, murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV), murine sarcoma 3611 oncogene 1, NS5, Oncogene RAF1, OTTHUMP00000207813, OTTHUMP00000209389, proto-oncogene c-RAF, RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, Raf-1 proto-oncogene, serine/threonine kinase, sarcoma 3611 oncogene, v-Raf, v-raf-1 leukemia viral oncogene 1, vraf1 murine le, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1, v-raf-leukemia viral oncogene 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110157, 24703, 5894
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P04049, P11345, Q99N57
Gene Symbols: Raf1
Immunogen: E.coli-derived human Raf1 recombinant protein (Position: Y364-Q451).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
c-Raf
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Raf1
Gene Alias:
6430402F14Rik, AA990557, BB129353, CMD1NN, CRAF, C-RAF, C-Raf proto-oncogene, serine/threonine kinase, Craf1, Craf1 transforming, D830050J10Rik, EC 2.7.11.1, kinase Raf1, murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV), murine sarcoma 3611 oncogene 1, NS5, Oncogene RAF1, OTTHUMP00000207813, OTTHUMP00000209389, proto-oncogene c-RAF, RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, Raf-1 proto-oncogene, serine/threonine kinase, sarcoma 3611 oncogene, v-Raf, v-raf-1 leukemia viral oncogene 1, vraf1 murine le, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1, v-raf-leukemia viral oncogene 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110157, 24703, 5894
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P04049, P11345, Q99N57
Gene Symbols:
Raf1
Immunogen:
E.coli-derived human Raf1 recombinant protein (Position: Y364-Q451).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG