PIPA595629
tPA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595629-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA595629 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
tPA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PLAT
Gene Alias
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18791, 25692, 5327
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
P00750, P11214, P19637
Gene Symbols
PLAT
Immunogen
A synthetic peptide corresponding to a sequence of human PLAT (QKDVPGVYTKVTNYLDWIRDNMRP).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- TPA converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen
- By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physio pathological events
- It specifically cleaves the Arg- -Val bond in plasminogen to form plasmin, and is comprised of a heterodimer of chain A and chain B held by a disulfide bond
- TPA binds to fibrin with high affinity
- This interaction leads to an increase in the catalytic efficiency of the enzyme between 100-and 1000-fold, due to an increase in affinity for plasminogen
- Similarly, binding to heparin increases the activation of plasminogen
- Binding to laminin and fibronectin has also been demonstrated
- TPA also binds to mannose receptor and the low-density lipoprotein receptor-related protein (LRP1)
- These proteins are involved in TPA clearance
- TPA binds to annexin II and to cytokeratin 8
- As yet unidentified interactions on endothelial cells and vascular smooth muscle cells (VSMC) lead to a 100-fold stimulation of plasminogen activation
- In addition, binding to VSMC reduces TPA inhibition by PAI-1 by 30-fold.
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Antigen: tPA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLAT
Gene Alias: 3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18791, 25692, 5327
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P00750, P11214, P19637
Gene Symbols: PLAT
Immunogen: A synthetic peptide corresponding to a sequence of human PLAT (QKDVPGVYTKVTNYLDWIRDNMRP).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
tPA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLAT
Gene Alias:
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18791, 25692, 5327
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P00750, P11214, P19637
Gene Symbols:
PLAT
Immunogen:
A synthetic peptide corresponding to a sequence of human PLAT (QKDVPGVYTKVTNYLDWIRDNMRP).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RhoB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RHOB
Gene Alias: AA017882, Aplysia RAS-related homolog 6, aplysia ras-related homolog B, Arh6, Arhb, h6, MST081, MSTP081, oncogene RHO H6, ras homolog B, ras homolog family member B, ras homolog gene family, member AB, ras homolog gene family, member B, Rho, rho cDNA clone 6, rhoB, RHOH6, Rho-related GTP-binding protein RhoB
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11852, 388, 64373
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P62745, P62746, P62747
Gene Symbols: RHOB
Immunogen: A synthetic peptide corresponding to a sequence of human RHOB (NKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLE).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RhoB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RHOB
Gene Alias:
AA017882, Aplysia RAS-related homolog 6, aplysia ras-related homolog B, Arh6, Arhb, h6, MST081, MSTP081, oncogene RHO H6, ras homolog B, ras homolog family member B, ras homolog gene family, member AB, ras homolog gene family, member B, Rho, rho cDNA clone 6, rhoB, RHOH6, Rho-related GTP-binding protein RhoB
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11852, 388, 64373
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P62745, P62746, P62747
Gene Symbols:
RHOB
Immunogen:
A synthetic peptide corresponding to a sequence of human RHOB (NKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLE).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RMI2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RMI2
Gene Alias: A630055G03Rik, BLAP18, BLM-associated protein of 18 kDa, C16orf75, Gm537, Gm929, hRMI2, RecQ mediated genome instability 2, recQ-mediated genome instability protein 2, RGD1563163, RMI2, RMI2, RecQ mediated genome instability 2, homolog, RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae), similar to hypothetical protein MGC24665
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116028, 223970, 497856
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q3UPE3, Q96E14
Gene Symbols: RMI2
Immunogen: A synthetic peptide corresponding to a sequence of human RMI2 (KMTDLSDNPIHESMWELEVEDLHRNIP).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RMI2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RMI2
Gene Alias:
A630055G03Rik, BLAP18, BLM-associated protein of 18 kDa, C16orf75, Gm537, Gm929, hRMI2, RecQ mediated genome instability 2, recQ-mediated genome instability protein 2, RGD1563163, RMI2, RMI2, RecQ mediated genome instability 2, homolog, RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae), similar to hypothetical protein MGC24665
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116028, 223970, 497856
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q3UPE3, Q96E14
Gene Symbols:
RMI2
Immunogen:
A synthetic peptide corresponding to a sequence of human RMI2 (KMTDLSDNPIHESMWELEVEDLHRNIP).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RRBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RRBP1
Gene Alias: 1700087N07Rik, 180 kDa ribosome receptor homolog, 5730465C04Rik, ES/130, ES/130-related protein, ES130, hES, KIAA1398, mKIAA1398, mRRp, mRRp0, mRRp1.8, mRRp10, mRRp15a, mRRp15b, mRRp16.8, mRRp2, mRRp41, mRRp47, mRRp5.4, p180, ribosome binding protein 1, ribosome binding protein 1 homolog 180kDa (dog), ribosome receptor protein, Ribosome-binding protein 1, RP11-462D18.3, Rrbp1, RRp
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311483, 6238, 81910
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q99PL5, Q9P2E9
Gene Symbols: RRBP1
Immunogen: A synthetic peptide corresponding to a sequence of human RRBP1 (EKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAED).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RRBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RRBP1
Gene Alias:
1700087N07Rik, 180 kDa ribosome receptor homolog, 5730465C04Rik, ES/130, ES/130-related protein, ES130, hES, KIAA1398, mKIAA1398, mRRp, mRRp0, mRRp1.8, mRRp10, mRRp15a, mRRp15b, mRRp16.8, mRRp2, mRRp41, mRRp47, mRRp5.4, p180, ribosome binding protein 1, ribosome binding protein 1 homolog 180kDa (dog), ribosome receptor protein, Ribosome-binding protein 1, RP11-462D18.3, Rrbp1, RRp
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311483, 6238, 81910
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q99PL5, Q9P2E9
Gene Symbols:
RRBP1
Immunogen:
A synthetic peptide corresponding to a sequence of human RRBP1 (EKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAED).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG