PIPA595668

Phospho-DENND3 (Ser554) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595668-Each-of-1 In Stock ₹ 47,015.22

PIPA595668 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Phospho-DENND3 (Ser554)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DENND3

Gene Alias

AI447457, DENN domain containing 3, DENN domain-containing protein 3, DENN/MADD domain containing 3, Dennd3, E030003N15Rik, KIAA0870

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22898

Content And Storage

-20°, C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.25 mg/mL

Formulation

10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.

A2RUS2

Gene Symbols

DENND3

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser554 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Antigen Affinity Purified from Pooled Serum Guanine nucleotide exchange factor (GEF) activating RAB12
  • Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form (PubMed:20937701)
  • Regulates autophagy in response to starvation through RAB12 activation
  • Starvation leads to ULK1/2-dependent phosphorylation of Ser-472 and Ser-490, which in turn allows recruitment of 14-3-3 adapter proteins and leads to up-regulation of GEF activity towards RAB12
  • Also plays a role in protein transport from recycling endosomes to lysosomes, regulating, for instance, the degradation of the transferrin receptor and of the amino acid transporter PAT4 (PubMed:20937701)
  • Starvation also induces phosphorylation at Tyr-858, which leads to up-regulated GEF activity and initiates autophagy
  • [UniProt]

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Img

Thermo Scientific

PIPA595668

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Antigen:
Phospho-DENND3 (Ser554)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DENND3

Gene Alias:
AI447457, DENN domain containing 3, DENN domain-containing protein 3, DENN/MADD domain containing 3, Dennd3, E030003N15Rik, KIAA0870

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22898

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
A2RUS2

Gene Symbols:
DENND3

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser554 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595669

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Antigen:
Phospho-AKT1 (Thr342)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
Akt, Akt kinase, AKT serine/threonine kinase 1, Akt/PKB, akt1, AKT1 kinase, AKT1m, Akt1m protein, Akt1-PA, Akt1-PB, Akt1-PC, Akt1-PD, Akt1-PE, CAKT, C-AKT, CG4006, CG4006-PA, CG4006-PB, CG4006-PC, CG4006-PD, CG4006-PE, CWS6, dAkt, D-Akt, dAkt kinase, dAKT/dPKB, dAkt/PKB, DAKT1, DAKT1/PKB, Dmel\CG4006, Dmel_CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, l(3)04226, l(3)89Bq, murine thymoma viral (v-akt) oncogene homolog 1, pAkt, P-AKT, PKB, PKB alpha, PKB beta, PKB gamma, PKB/AKT, PKB/dAKT, PKBalpha, PKB-ALPHA, PKBG, PRKBA, protein kinase B, Protein kinase B alpha, protein kinase B-alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC protein kinase alpha RAC-PK alpha, RAC serine/threonine protein kinase, RAC serine/threonine-protein kinase, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RacPK, RAC-PK-alpha, RAC-PK-beta, RAC-PK-gamma, related to A and C kinases, related to PKA to PKC protein kinases, related to the A and C kinases, SD10374p, serine/threonine protein kinase, serine-threonine protein kinase, Thymoma viral proto-oncogene, thymoma viral proto-oncogene 1, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
41957

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
Q8INB9

Gene Symbols:
AKT1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr342 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Drosophila

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595670

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Antigen:
Phospho-Aquaporin 2 (Ser261)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aqp2

Gene Alias:
ADH water channel, AQP 2, AQP CD, Aqp2, AQP-2, AQPCD, AQP-CD, aquaporin 2, aquaporin 2 (collecting duct), Aquaporin CD, Aquaporin2, aquaporin-2, Aquaporin-CD, Aquaporine 2, collecting duct water channel protein, cph, jpk, MGC34501, Water channel protein for renal collecting duct, water-channel aquaporin 2, WCH CD, WCHCD, WCH-CD

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11827, 25386, 359

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
P34080, P41181, P56402

Gene Symbols:
Aqp2

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser261 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595671

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Antigen:
Phospho-GluR2 (Ser880)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gria2

Gene Alias:
AMPA selective glutamate receptor, AMPA-selective glutamate receptor 2, GluA2, Glur2, GluR-2, GLURB, GluR-B, GluR-K2, glutamate ionotropic receptor AMPA type subunit 2, glutamate receptor, glutamate receptor 2, glutamate receptor B, glutamate receptor B flip isoform, glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA2 (alpha 2), GRIA2, HBGR2, OTTHUMP00000165324, OTTHUMP00000220942, OTTHUMP00000220943

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29627

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
∽0.25 mg/mL

Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5

Gene Accession No.:
P19491

Gene Symbols:
Gria2

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser880 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG