PIPA595811
NOTUM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595811-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA595811 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
NOTUM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NOTUM
Gene Alias
[Wnt protein] O-palmitoleoyl-L-serine hydrolase, 5730593N15Rik, hNOTUM, NOTUM, notum pectinacetylesterase homolog, notum pectinacetylesterase homolog (Drosophila), NOTUM, palmitoleoyl-protein carboxylesterase, OK/SW-CL.30, Palmitoleoyl-protein carboxylesterase NOTUM, protein notum homolog, RGD1307119
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
147111
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.23 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q6P988
Gene Symbols
NOTUM
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human NOTUM (NP_8485883)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: SEGRKTWRRR GQQPPPPPRT EAAPAAGQPV ESFPLDFTAV EGNMDSFMAQ VKSLAQSLYP CSAQQLNEDL RLHLLLNTSV TCNDGSPAGY YLKESRGSRR WLLFLEGGWY CFNRENCDSR YDTMRRLMSS RDWPRTRTGT GILSSQPEEN PYWWNANMVF IPYCSSDVWS GASSKSEKNE YAFMGALIIQ EVVRELLGRG LSGAKVLLLA GSSAGGTGVL LNVDRVAEQL EKLGYPAIQV RGLADSGWFL DNKQYRHTDC VDTITCAPTE AIRRGIRYWN GVVPERCRRQ FQEGEEWNCF F; Positive Samples: BxPC-3, HepG2 Genetic studies in Drosophila have revealed a novel secreted antagonist for Wingless (Wg) signaling, referred to as Notum/Wingful (Wf)
- Wf/Notum encodes a protein of 430 amino acid residues, which is related to plant pectin acetylesterases of the a/beta-hydrolase superfamily
- The main target of Notum action appears to be cell surface proteoglycans Dally and/or Dally-like (Dlp)
- Notum governs the extracellular Wg morphogen distribution via Dally and Dlp
- Also, like some vertebrate Wnt antagonists, notum expression is activated by Wg signaling, revealing the existence of a feedback control mechanism in which Wg modifies its own gradient distribution
- In vertebrate, proteoglycans related to Dally and Dlp likely play important roles in Wnt signaling which encodes a glypican that is required for Wnt-11 signaling
- A single ortholog of Notum exists in the mouse and the human genome, implying that a similar regulatory mechanism may exist in vertebrates.
Compare Similar Items
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Antigen: NOTUM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOTUM
Gene Alias: [Wnt protein] O-palmitoleoyl-L-serine hydrolase, 5730593N15Rik, hNOTUM, NOTUM, notum pectinacetylesterase homolog, notum pectinacetylesterase homolog (Drosophila), NOTUM, palmitoleoyl-protein carboxylesterase, OK/SW-CL.30, Palmitoleoyl-protein carboxylesterase NOTUM, protein notum homolog, RGD1307119
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 147111
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.23 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q6P988
Gene Symbols: NOTUM
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human NOTUM (NP_8485883)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NOTUM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOTUM
Gene Alias:
[Wnt protein] O-palmitoleoyl-L-serine hydrolase, 5730593N15Rik, hNOTUM, NOTUM, notum pectinacetylesterase homolog, notum pectinacetylesterase homolog (Drosophila), NOTUM, palmitoleoyl-protein carboxylesterase, OK/SW-CL.30, Palmitoleoyl-protein carboxylesterase NOTUM, protein notum homolog, RGD1307119
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
147111
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.23 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q6P988
Gene Symbols:
NOTUM
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human NOTUM (NP_8485883)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SPC24
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SPC24
Gene Alias: 2410030K01Rik, AV109292, hSpc24, kinetochore protein Spc24, SPBC24, SPC24, SPC24, NDC80 kinetochore complex component, SPC24, NDC80 kinetochore complex component, homolog, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae), spindle pole body component 24 homolog
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 147841, 67629
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.12 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q8NBT2, Q9D083
Gene Symbols: SPC24
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SPC24 (NP_8723191)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SPC24
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SPC24
Gene Alias:
2410030K01Rik, AV109292, hSpc24, kinetochore protein Spc24, SPBC24, SPC24, SPC24, NDC80 kinetochore complex component, SPC24, NDC80 kinetochore complex component, homolog, SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae), spindle pole body component 24 homolog
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
147841, 67629
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.12 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q8NBT2, Q9D083
Gene Symbols:
SPC24
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SPC24 (NP_8723191)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RBM46
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBM46
Gene Alias: cancer/testis antigen 68, CT68, EG633285, ENSMUSG00000033882, fe11d09, Gm761, LOW QUALITY PROTEIN: probable RNA-binding protein 46, probable RNA-binding protein 46, RBM46, RGD1560205, RNA binding motif protein 46, RNA-binding motif protein 46, wu:fe11d09, zgc:153695
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 166863, 310548, 633285
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.71 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P86049, Q8TBY0
Gene Symbols: RBM46
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human RBM46 (NP_6594161)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RBM46
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBM46
Gene Alias:
cancer/testis antigen 68, CT68, EG633285, ENSMUSG00000033882, fe11d09, Gm761, LOW QUALITY PROTEIN: probable RNA-binding protein 46, probable RNA-binding protein 46, RBM46, RGD1560205, RNA binding motif protein 46, RNA-binding motif protein 46, wu:fe11d09, zgc:153695
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
166863, 310548, 633285
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.71 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P86049, Q8TBY0
Gene Symbols:
RBM46
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human RBM46 (NP_6594161)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CCER1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCER1
Gene Alias: C12orf12, CCER1, Coiled-coil domain-containing glutamate-rich protein 1, coiled-coil glutamate rich protein 1, coiled-coil glutamate-rich protein 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 196477, 500825, 66716
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.35 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q6AY45, Q8TC90, Q9CQL2
Gene Symbols: CCER1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Ccer1 (NP_0800001)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CCER1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCER1
Gene Alias:
C12orf12, CCER1, Coiled-coil domain-containing glutamate-rich protein 1, coiled-coil glutamate rich protein 1, coiled-coil glutamate-rich protein 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
196477, 500825, 66716
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q6AY45, Q8TC90, Q9CQL2
Gene Symbols:
CCER1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Ccer1 (NP_0800001)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG