PIPA595907

XBP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595907-Each-of-1 In Stock ₹ 44,705.10

PIPA595907 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

XBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Xbp1

Gene Alias

D11Ertd39e, Hepatocarcinogenesis-related transcription factor, HTF, OTTHUMP00000028682, Tax-responsive element-binding protein 5, tax-responsive element-binding protein 5 homolog, TREB5, TREB-5, X-box binding protein 1, X-box-binding protein 1, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1, luminal form, XBP1, XBP-1, XBP2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22433, 289754, 7494

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.66 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O35426, P17861, Q9R1S4

Gene Symbols

Xbp1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 277-376 of human XBP1 (NP_001073007.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive Samples: 293T, NCI-H460, Mouse eye, Rat liver, Rat eye; Cellular Location: Cytoplasm, Endoplasmic reticulum membrane, Endoplasmic reticulum, Membrane, Nucleus, Peripheral membrane protein, Single-pass type II membrane protein Immunogen sequence: NVVVKIEEAP LSPSENDHPE FIVSVKEEPV EDDLVPELGI SNLLSSSHCP KPSSCLLDAY SDCGYGGSLS PFSDMSSLLG VNHSWEDTFA NELFPQLISV XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box
  • This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter
  • It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator
  • It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)
  • The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor
  • The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress
  • A pseudogene of XBP1 has been identified and localized to chromosome 5.

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Img

Thermo Scientific

PIPA595907

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Antigen:
XBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e, Hepatocarcinogenesis-related transcription factor, HTF, OTTHUMP00000028682, Tax-responsive element-binding protein 5, tax-responsive element-binding protein 5 homolog, TREB5, TREB-5, X-box binding protein 1, X-box-binding protein 1, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1, luminal form, XBP1, XBP-1, XBP2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22433, 289754, 7494

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.66 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O35426, P17861, Q9R1S4

Gene Symbols:
Xbp1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 277-376 of human XBP1 (NP_001073007.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595908

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Antigen:
HDAC6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HDAC6

Gene Alias:
CPBHM, FLJ16239, Hd6, HDA6, Hdac5, Hdac6, histone deacetylase 5, histone deacetylase 6, Histone deacetylase mHDA2, JM21, KIAA0901, mHDA2, PPP1R90, protein phosphatase 1, regulatory subunit 90, scurfy candidate 6, Sfc6

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10013, 15185, 84581

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.59 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9UBN7, Q9Z2V5

Gene Symbols:
HDAC6

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HDAC6 (NP_0060352)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595910

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Antigen:
ARSA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARSA

Gene Alias:
ARSA, ARSA1, ARSA-I, Arylsulfatase A, Arylsulfatase A component B, Arylsulfatase A component C, As2, As-2, ASA, AS-A, ASNA-I, ATPase ASNA1, AW212749, cerebroside-sulfatase, EC 3.1.6.8, GET3, hASNA-I, MLD, TISP73, TRC40

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11883, 410

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.22 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P15289, P50428

Gene Symbols:
ARSA

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human ARSA (NP_0004783)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595911

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Antigen:
RUNX1T1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RUNX1T1

Gene Alias:
acute myelogenous leukemia 1 translocation 1 protein, acute myelogenous leukemia 1 translocation 1, cyclin-D related, AML1-MTG8, AML1T1, Cbfa2t1, CBFA2T1 identified gene homolog, CBFA2T1 isoform r1t1-11a61, CBFA2T1 isoform r1t1-11a62, CBFA2T1 isoform r1t1-11a63, CBFA2T1 isoform r1t1-11a64, CBFA2T1 isoform r1t1-11a65, CBFA2T1 isoform r1t1-7a47, CBFA2T1 isoform r1t1-7a48, CBFA2T1 isoform r1t1-7a49, CBFA2T1 isoform r1t1-7a50, CBFA2T1 isoform r1t1-7a51, CBFA2T1 isoform r1t1-7a52, CBFA2T1 isoform r1t1-7d53, CBFA2T1 isoform r1t1-7d54, CBFA2T1 isoform r1t1-7d55, CBFA2T1 isoform r1t1-7d56, CBFA2T1 isoform r1t1-8a57, CBFA2T1 isoform r1t1-8a58, CBFA2T1 isoform r1t1-8a59, CBFA2T1 isoform r1t1-8a60, Cbfa2t1h, CDR, core-binding factor, runt domain, alpha subunit 2, translocated to, 1, core-binding factor, runt domain, alpha subunit 2, translocated to, 1, cyclin D-related, cyclin D-related, Cyclin-D-related protein, Eight twenty one protein, ETO, LOW QUALITY PROTEIN: protein CBFA2T1, MGC2796, MTG8,

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
862

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.08 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q06455

Gene Symbols:
RUNX1T1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-403 of human RUNX1T1 (NP_7835521)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG