PIPA595921

AIRE Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595921-Each-of-1 In Stock ₹ 44,705.10

PIPA595921 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

AIRE

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Aire

Gene Alias

Aire, AIRE protein, AIRE1, APECED, APECED protein, APECED protein homolog, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog, Autoimmune regulator, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), autoimmune regulator AIRE1a, LOW QUALITY PROTEIN: autoimmune regulator, OTTHUMP00000109529, PGA1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11634, 294328, 326

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.57 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O43918, Q9Z0E3

Gene Symbols

Aire

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 30-130 of human AIRE (NP_0003741)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: MCF7, U-937, HT-29, OVCAR3, SW620, Mouse kidney, Mouse liver; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: HALADHDVVP EDKFQETLHL KEKEGCPQAF HALLSWLLTQ DSTAILDFWR VLFKDYNLER YGRLQPILDS FPKDVDLSQP RKGRKPPAVP KALVPPPRLP T AIRE is a transcriptional regulator protein that binds to DNA as a dimer and tetramer, but not as a monomer, and may be involved in the regulation of gene expression
  • A nuclear protein, AIRE is a 545 amino acid protein with an HSR domain, two PHD type zinc fingers, and a SAND domain, and may be present in soluble high-molecular-weight complexes
  • It may form homodimer, homotetramer and also nuclear bodies and interacts with the transcriptional coactivator CBP and CREBBP
  • Three isoforms of AIRE are reported and one of them is predicted to be a candidate for nuclear-mediated decay (NMD)
  • AIRE is involved in immune regulation and is known to mediate E3 ubiquitin ligase activity
  • Defects in AIRE are responsible for the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595921

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Antigen:
AIRE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire, AIRE protein, AIRE1, APECED, APECED protein, APECED protein homolog, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog, Autoimmune regulator, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), autoimmune regulator AIRE1a, LOW QUALITY PROTEIN: autoimmune regulator, OTTHUMP00000109529, PGA1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634, 294328, 326

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O43918, Q9Z0E3

Gene Symbols:
Aire

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 30-130 of human AIRE (NP_0003741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595922

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Antigen:
Cyclin D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCND2

Gene Alias:
2600016F06Rik, AI256817, BF642806, C86853, CCND2, cD2, cyclin D2, Cyl-2, G1/S-specific cyclin-D2, KIAK0002, MGC102758, MPPH3, Vin1, Vin-1, Vin-1 proto-oncogene

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12444, 64033, 894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.11 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P30279, P30280, Q04827

Gene Symbols:
CCND2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human Cyclin D2 (NP_0017501)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595923

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Antigen:
IGF2BP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF2BP2

Gene Alias:
C330012H03Rik, Hepatocellular carcinoma autoantigen p62, IGF2 mRNA-binding protein 2, IGF2BP2, IGF-II mRNA-binding protein 2, Imp2, IMP-2, insulin like growth factor 2 mRNA binding protein 2, insulin-like growth factor 2 mRNA binding protein 2, insulin-like growth factor 2 mRNA-binding protein 2, insulin-like growth factor 2, binding protein 2, Neilsen, p62, RGD1305614, VICKZ family member 2, VICKZ2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10644, 303824, 319765

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.41 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q5SF07, Q9Y6M1

Gene Symbols:
IGF2BP2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-599 of human IGF2BP2/IMP2 (NP_0065393)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595924

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Antigen:
HMBS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hmbs

Gene Alias:
alternative name: porphobilinogen deaminase, HEM3, hemC, HMBS, Hydroxymethylbilane synthase, PBG D, PBGD, PBG-D, PORC, Porphobilinogen deaminase, porphyria, acute, Chester type, pre-uroporphyrinogen synthase, similar to Porphobilinogen deaminase (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D), T25658, Ups, uroporphyrinogen I synthase, uroporphyrinogen I synthetase, URO-S, Uros1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15288, 3145

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
6.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P08397, P22907

Gene Symbols:
Hmbs

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-361 of human HMBS (NP_0001812)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG