PIPA595931

HGS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595931-Each-of-1 In Stock ₹ 44,705.10

PIPA595931 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HGS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HGS

Gene Alias

hepatocyte growth factor-regulated tyrosine kinase substrate, HGF-regulated tyrosine kinase substrate, HGNC:4897, Hgr, Hgs, Hrs, Hrs2, human growth factor-regulated tyrosine kinase substrate, protein pp110, SNAP-25-interacting protein Hrs-2, ZFYVE8

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15239, 56084, 9146

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

0.11 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

O14964, Q99LI8, Q9JJ50

Gene Symbols

HGS

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 548-777 of human HGS (NP_0047031)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: EQQKQTVQMR AQMPAFPLPY AQLQAMPAAG GVLYQPSGPA SFPSTFSPAG SVEGSPMHGV YMSQPAPAAG PYPSMPSTAA DPSMVSAYMY PAGATGAQAA PQAQAGPTAS PAYSSYQPTP TAGYQNVASQ APQSLPAISQ PPQSSTMGYM GSQSVSMGYQ PYNMQNLMTT LPSQDASLPP QQPYIAGQQP MYQQMAPSGG PPQQQPPVAQ QPQAQGPPAQ GSEAQLISFD; Positive Samples: THP-1, OVCAR3, MCF7, HepG2, Mouse testis, Rat testis; Cellular Location: Cytoplasm, Cytoplasmic side, Early endosome membrane, Endosome, Peripheral membrane protein, multivesicular body membrane HGS is involved in intracellular signal transduction mediated by cytokines and growth factors
  • When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF
  • It could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin
  • HGS may concentrate ubiquitinated receptors within clathrin-coated regions
  • It is involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM
  • This complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes
  • HGS may contribute to the efficient recruitment of SMADs to the activin receptor complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595931

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Antigen:
HGS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HGS

Gene Alias:
hepatocyte growth factor-regulated tyrosine kinase substrate, HGF-regulated tyrosine kinase substrate, HGNC:4897, Hgr, Hgs, Hrs, Hrs2, human growth factor-regulated tyrosine kinase substrate, protein pp110, SNAP-25-interacting protein Hrs-2, ZFYVE8

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15239, 56084, 9146

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
0.11 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O14964, Q99LI8, Q9JJ50

Gene Symbols:
HGS

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 548-777 of human HGS (NP_0047031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595932

--


Antigen:
BIN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BIN1

Gene Alias:
ALP-1, AMPH 2, Amph2, amphiphysin 2, amphiphysin II, amphiphysin IIamph2, amphiphysin-like, amphiphysin-like protein, AMPHL, Bin1, box dependant MYC interacting protein 1, box-dependent myc-interacting protein 1, BRAMP-2, bridging integrator 1, DKFZp547F068, MGC10367, MGC105358, myc box dependent interacting protein 1, myc box-dependent-interacting protein 1, SH3 domain-containing protein 9, SH3P9, similar to bridging integrator 1 isoform 9

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117028, 274

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.66 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O00499, O08839

Gene Symbols:
BIN1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-409 of human BIN1 (NP_6476011)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595934

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Antigen:
CK1 epsilon

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSNK1E

Gene Alias:
AI426939, AI551861, AW457082, casein kinase 1, casein kinase 1 epsilon, casein kinase 1, epsilon, casein kinase I isoform epsilon, CK1e, CK1epsilon, CKI, epsilon, CKIe, CKIepsilon, CKI-epsilon, Csnk1e, HCKIE, KC1 epsilon, KC1epsilon, MGC10398, OTTHUMP00000063258, OTTHUMP00000063263, RP1-5O6.1, tau

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1454, 27373, 58822

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P49674, Q9JMK2

Gene Symbols:
CSNK1E

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 247-416 of human CSNK1E (NP_6894071)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595935

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Antigen:
XRCC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XRCC2

Gene Alias:
4921524O04Rik, 8030409M04Rik, DKFZp781P0919, DNA repair protein XRCC2, FANCU, RAD51, RecA, recA/RAD51 family protein, RGD1564823, X-ray repair complementing defective repair in Chinese hamster cells 2, X-ray repair cross complementing 2, X-ray repair cross complementing protein 2, X-ray repair cross-complementing protein 2, Xrcc2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
499966, 57434, 7516

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration:
2.03 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O43543, Q9CX47

Gene Symbols:
XRCC2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human XRCC2 (NP_0054221)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG