PIPA596068

CHK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA596068-Each-of-1 In Stock ₹ 44,705.10

PIPA596068 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CHK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11200, 114212, 50883

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

1.35 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O96017, Q9Z265

Gene Symbols

Chek2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Chk2 (NP_0091251)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: MSRESDVEAQ QSHGSSACSQ PHGSVTQSQG SSSQSQGISS SSTSTMPNSS QSSHSSSGTL SSLETVSTQE LYSIPEDQEP EDQEPEEPTP APWARLWALQ DGFANLECVN DNYWFGRDKS CEYCFDEPLL KRTDKYRTYS KKHFRIFREV GPKNSYIAYI EDHSGNGTFV NTELVGKGKR RPLNNNSEIA LSLSRNKVFV FFDLTVDDQS VYPKALRDEY; Positive Samples: HT-29, HeLa, DU145, H460, Raji, MCF-7, K-562, Jurkat; Cellular Location: Nucleus, Nucleus, PML body, nucleoplasm CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway
  • A mutation in CHK2 has been linked to cancer
  • CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Compare Similar Items

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Img

Thermo Scientific

PIPA596068

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Antigen:
CHK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11200, 114212, 50883

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
1.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O96017, Q9Z265

Gene Symbols:
Chek2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Chk2 (NP_0091251)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596069

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Antigen:
LETMD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LETMD1

Gene Alias:
1110019O13Rik, AI593524, BB130465, BB235638, Cervical cancer 1 proto-oncogene protein p40, cervical cancer proto-oncogene 2 protein, Cervical cancer receptor, HCCR1, HCCR-1, HCCR-2, HCRR-2, LETM1 domain containing 1, LETM1 domain-containing protein 1, LETMD1, MCC-32, Mccr, regulator of TP53, RGD1310591

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25875, 681352, 68614

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q6P1Q0, Q924L1

Gene Symbols:
LETMD1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 161-360 of human LETMD1 (NP_0562313)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596070

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Antigen:
SCCPDH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCCPDH

Gene Alias:
AW214504, C330023F11Rik, CGI 49, CGI49, CGI-49, hypothetical protein LOC507289, NET11, probable saccharopine dehydrogenase, RGD1311440, RP11-439E19.2, saccharopine dehydrogenase (putative), saccharopine dehydrogenase-like oxidoreductase, Sccpdh, SCPDH

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109232, 51097

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.61 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q8NBX0, Q8R127

Gene Symbols:
SCCPDH

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human SCCPDH (NP_0570862)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596071

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Antigen:
SPINLW1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPPIN

Gene Alias:
1700024E17Rik, cancer/testis antigen 71, cancer/testis antigen 72, CT71, CT72, dJ461P17.2, epididymal peptidase inhibitor, epididymal protease inhibitor, EPPIN, EPPIN1, EPPIN2, EPPIN3, protease inhibitor WAP7, serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin), serine protease inhibitor-like with Kunitz and WAP domains 1, serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin), Spinlw1, WAP four-disulfide core domain protein 7, WAP four-disulfide core domain protein 8, WAP7, WFDC7, Wfdc8

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57119, 685161, 75526

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
D4A2Z2, O95925, Q9DA01

Gene Symbols:
EPPIN

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-133 of human EPPIN (NP_0651311)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG