PIPA596151
ACK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596151-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA596151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
ACK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TNK2
Gene Alias
ACK, ACK1, Ack-1, Activated CDC42 kinase 1, activated Cdc42-associated kinase 1, activated p21cdc42Hs kinase, Cdc42 GTPase-inhibiting protein, Cdgip, Non-receptor protein tyrosine kinase Ack, p21cdc42Hs, P21cdc42Hs kinase, Pyk1, Tnk2, tnk2 {ECO:0000250, tyrosine kinase non receptor 2, tyrosine kinase non-receptor protein 2, tyrosine kinase, non-receptor, 2, UniProtKB:Q07912}
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10188, 303882, 51789
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.32 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
O54967, Q07912, Q5U2X5
Gene Symbols
TNK2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 920-1038 of human TNK2 (NP_0057723)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KANFSTNNSN PGARPPPPRA TARLPQRGCP GDGPEAGRPA DKIQMAMVHG VTTEECQAAL QCHGWSVQRA AQYLKVEQLF GLGLRPRGEC HKVLEMFDWN LEQAGCHLLG SWGPAHHKR Positive Samples: SW620, HT-29, MCF7, Raji; Cellular Location: Cell junction, Cell membrane, Cytoplasmic side, Cytoplasmic vesicle, Cytoplasmic vesicle membrane, Endosome, Membrane, Nucleus, Peripheral membrane protein, adherens junction, clathrin-coated pit, clathrin-coated vesicle TNK2 (ACK) (activated Cdc42-associated kinase) is a non-receptor tyrosine kinase that signals downstream of Cdc42
- TNK2 is known to be involved in tumorigenesis and metastasis, particularly in prostate cancer
- Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1
- May be involved both in adult synaptic function and plasticity and in brain development
- Activates AKT1 by phosphorylating it on 'Tyr-176'
- Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs)
- Phosphorylates WWOX on 'Tyr-287'
- Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins
- Contributes to the control of AXL receptor levels
- Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR
- Phosphorylates WASP.
Compare Similar Items
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Antigen: ACK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNK2
Gene Alias: ACK, ACK1, Ack-1, Activated CDC42 kinase 1, activated Cdc42-associated kinase 1, activated p21cdc42Hs kinase, Cdc42 GTPase-inhibiting protein, Cdgip, Non-receptor protein tyrosine kinase Ack, p21cdc42Hs, P21cdc42Hs kinase, Pyk1, Tnk2, tnk2 {ECO:0000250, tyrosine kinase non receptor 2, tyrosine kinase non-receptor protein 2, tyrosine kinase, non-receptor, 2, UniProtKB:Q07912}
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10188, 303882, 51789
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.32 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O54967, Q07912, Q5U2X5
Gene Symbols: TNK2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1038 of human TNK2 (NP_0057723)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNK2
Gene Alias:
ACK, ACK1, Ack-1, Activated CDC42 kinase 1, activated Cdc42-associated kinase 1, activated p21cdc42Hs kinase, Cdc42 GTPase-inhibiting protein, Cdgip, Non-receptor protein tyrosine kinase Ack, p21cdc42Hs, P21cdc42Hs kinase, Pyk1, Tnk2, tnk2 {ECO:0000250, tyrosine kinase non receptor 2, tyrosine kinase non-receptor protein 2, tyrosine kinase, non-receptor, 2, UniProtKB:Q07912}
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10188, 303882, 51789
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.32 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O54967, Q07912, Q5U2X5
Gene Symbols:
TNK2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 920-1038 of human TNK2 (NP_0057723)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PCBP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PCBP2
Gene Alias: Alpha CP2, Alpha-CP2, alphaCP-2, AW412548, CBP, CTBP, fb36h02, Heterogeneous nuclear ribonucleoprotein E2, heterogeneous nuclear ribonucleoprotein X, heterogenous nuclear ribonucleoprotein E2, hnRNP E2, hnRNP X, HNRNPE2, hnRNP-E2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, Pcbp2, pcbp2 protein, PCBP3, poly(rC) binding protein 2, poly(rC)-binding protein 2, Putative heterogeneous nuclear ribonucleoprotein X, rCbinding protein 2, wu:fb36h02, zgc:55964
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18521, 363005, 5094
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.94 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q15366, Q61990
Gene Symbols: PCBP2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human hnRNP E2/PCBP2 (NP_0011223831)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PCBP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PCBP2
Gene Alias:
Alpha CP2, Alpha-CP2, alphaCP-2, AW412548, CBP, CTBP, fb36h02, Heterogeneous nuclear ribonucleoprotein E2, heterogeneous nuclear ribonucleoprotein X, heterogenous nuclear ribonucleoprotein E2, hnRNP E2, hnRNP X, HNRNPE2, hnRNP-E2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, Pcbp2, pcbp2 protein, PCBP3, poly(rC) binding protein 2, poly(rC)-binding protein 2, Putative heterogeneous nuclear ribonucleoprotein X, rCbinding protein 2, wu:fb36h02, zgc:55964
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18521, 363005, 5094
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.94 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q15366, Q61990
Gene Symbols:
PCBP2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human hnRNP E2/PCBP2 (NP_0011223831)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Tenascin X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNXB
Gene Alias: EDS3, growth-inhibiting protein 45, hexabrachion-like protein, HXBL, tenascin XB, tenascin XB1, tenascin XB2, tenascin-X, TENX, Tn-mhc, Tnx, TN-X, TNXB, TNXB1, TNXB2, TNXB2tenascin XB1, TNXBS, TNXBSTNXTENX, VUR8, XB, XBS, XB-S, XBTN-X
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 415089, 81877
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.02 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P22105
Gene Symbols: TNXB
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_1158592)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Tenascin X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNXB
Gene Alias:
EDS3, growth-inhibiting protein 45, hexabrachion-like protein, HXBL, tenascin XB, tenascin XB1, tenascin XB2, tenascin-X, TENX, Tn-mhc, Tnx, TN-X, TNXB, TNXB1, TNXB2, TNXB2tenascin XB1, TNXBS, TNXBSTNXTENX, VUR8, XB, XBS, XB-S, XBTN-X
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
415089, 81877
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.02 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P22105
Gene Symbols:
TNXB
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_1158592)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD61
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITGB3
Gene Alias: antigen CD61, BDPLT16, BDPLT2, beta3 integrin, CD61, EGK_08849, glycoprotein GPIIIa, glycoprotein IIIa, GP3A, GPIIIa, GT, INGRB3, integrin beta 3, integrin beta 3 (Cd61), integrin beta-3, integrin beta-3 subunit, integrin subunit beta 3, integrin, beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITGB3, platelet glycoprotein IIIa, platelet glycoprotein IIIa integrin subunit beta 3, platelet gpIIIa, platelet membrane glycoprotein IIIa
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16416, 29302, 3690
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.04 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O54890, P05106
Gene Symbols: ITGB3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-430 of human Integrin beta 3 (ITGB3/CD61) (NP_0002032)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CD61
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITGB3
Gene Alias:
antigen CD61, BDPLT16, BDPLT2, beta3 integrin, CD61, EGK_08849, glycoprotein GPIIIa, glycoprotein IIIa, GP3A, GPIIIa, GT, INGRB3, integrin beta 3, integrin beta 3 (Cd61), integrin beta-3, integrin beta-3 subunit, integrin subunit beta 3, integrin, beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITGB3, platelet glycoprotein IIIa, platelet glycoprotein IIIa integrin subunit beta 3, platelet gpIIIa, platelet membrane glycoprotein IIIa
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16416, 29302, 3690
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.04 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O54890, P05106
Gene Symbols:
ITGB3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-430 of human Integrin beta 3 (ITGB3/CD61) (NP_0002032)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG