PIPA596168

PDCD4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA596168-Each-of-1 In Stock ₹ 47,614.14

PIPA596168 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

PDCD4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDCD4

Gene Alias

D19Ucla1, death up-regulated gene protein, death-upregulated, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor protein, nuclear antigen H731, Nuclear antigen H731-like, Pdcd4, programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death protein 4, Protein 197/15a, protein MA-3, RP11-348N5.4, Tis, topoisomerase-inhibitor suppressed protein

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18569, 27250

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q53EL6, Q61823

Gene Symbols

PDCD4

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_0552712)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: MDVENEQILN VNPADPDNLS DSLFSGDEEN AGTEEIKNEI NGNWISASSI NEARINAKAK RRLRKNSSRD SGRGDSVSDS GSDALRSGLT VPTSPKGRLL DRRSRSGKGR GLPKKGGAGG KGVWGTPGQV YDVEEVDVKD PNYDDDQENC VYETVVLPLD ERAFEKTLTP IIQEYFEHGD TNEVAEMLRD LNLGEMKSGV PVLAVSLALE GKASHREMTS KLLSDLCGTV MSTTDVEKSF DKLLKDLPEL ALDTPRAPQL; Positive Samples: MCF-7, HeLa, HepG2, Mouse thymus; Cellular Location: Cytoplasm, Nucleus Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation
  • During this process, the expression patterns of numerous genes are radically altered
  • One such gene is the programmed cell death protein 4 (PDCD4), whose expression was found to be upregulated in all cell lines following the onset of apoptosis
  • PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast, colon, lung and prostate
  • It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1
  • The kinase Akt regulates PDCD4 by phosphorylation, decreasing the ability of PDCD4 to interfere with the transactivation of AP-1-responsive promoter by c-Jun
  • There are two known isoforms of PDCD4.

Compare Similar Items

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Img

Thermo Scientific

PIPA596168

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Antigen:
PDCD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDCD4

Gene Alias:
D19Ucla1, death up-regulated gene protein, death-upregulated, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor protein, nuclear antigen H731, Nuclear antigen H731-like, Pdcd4, programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death protein 4, Protein 197/15a, protein MA-3, RP11-348N5.4, Tis, topoisomerase-inhibitor suppressed protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18569, 27250

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q53EL6, Q61823

Gene Symbols:
PDCD4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_0552712)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596169

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Antigen:
TBK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TBK1

Gene Alias:
1200008B05Rik, AI462036, AW048562, FLJ11330, FTDALS4, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, serine/threonine protein kinase TBK1, serine/threonine-protein kinase TBK1, T2K, TANK binding kinase 1, TANK-binding kinase 1, tbk, TBK1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29110, 299827, 56480

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.98 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
Q9UHD2, Q9WUN2

Gene Symbols:
TBK1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK (NP_0373861)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596172

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Antigen:
TPI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tpi1

Gene Alias:
AI255506, epididymis secretory protein Li 49, HEL-S-49, Methylglyoxal synthase, MGC88108, TIM, Tpi, TPI1, Tpi-1, TPID, triosephosphate isomerase, triose-phosphate isomerase, triosephosphate isomerase 1, triose-phosphate isomerase TPI1, unnamed protein product, YD9609.05C, YDR050C

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21991, 24849, 7167

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.39 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P17751, P48500, P60174

Gene Symbols:
Tpi1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human TPI1 (NP_0003561)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596173

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Antigen:
DARPP-32

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppp1r1b

Gene Alias:
AU040756, DARPP32, DARPP-32, dopamine- and cAMP-regulated neuronal phosphoprotein, dopamine and cAMP-regulated neuronal phosphoprotein 32, dopamine- and cAMP-regulated phosphoprotein DARPP-32, FLJ20940, IPPD, neuronal phosphoprotein DARPP-32, OTTHUMP00000164275, OTTHUMP00000164276, Ppp1r1b, PPR1B, protein pho, protein phosphatase 1 regulatory inhibitor subunit 1B, protein phosphatase 1 regulatory subunit 1B, protein phosphatase 1, regulatory (inhibitor) subunit 1B

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19049, 360616, 84152

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q60829, Q6J4I0, Q9UD71

Gene Symbols:
Ppp1r1b

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human DARPP32 (NP_1155682)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG