PIPA596354

GNAS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596354-Each-of-1 In Stock ₹ 44,705.10

PIPA596354 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GNAS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GNAS

Gene Alias

5530400H20Rik, A930027G11Rik, Adenylate cyclase-stimulating G alpha protein, AHO, ALEX, GNAS, NESP55, alpha-stimulatory subunit of GTP-binding protein, alternative gene product encoded by XL-exon, C130027O20Rik, C20orf45, dJ309F20.1.1, dJ806M20.3.3, Extra large alphas protein, G protein alpha subunit, G protein subunit alpha S, GAIPIRRH peptide, G-alpha-8, Galphas, Gnas, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, gnas {ECO:0000312, GNAS complex locus, GNAS complex locus, SCG6 (secretogranin VI), GNAS1, Gnasxl, Gnpas, GPIPIRRH peptide, GPSA, Gs alpha subunit, GSA, G-SALPHA60A, GSP, GTP-binding regulatory protein (G-s-alpha)., GTP-binding regulatory protein alpha subunit exon 1, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1, guanine nucleotide binding protein alpha s, guanine nucleotide binding protein alpha subunit, guanine nucleotide binding protein, alpha stimulating activity polypeptide 1, guanine nucleotide

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14683, 24896, 2778

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

2.14 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1

Gene Symbols

GNAS

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAS (NP_0005071)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: MGCLGNSKTE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK Positive Samples: BT-474, H460, SW620, Raji; Cellular Location: Cell membrane By similarity; Lipid-anchor By similarity Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseous heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors
  • This gene has a highly complex imprinted expression pattern
  • It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5' exons
  • Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes
  • However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual
  • In addition, one of the alternate 5' exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others
  • An antisense transcript exists, and may regulate imprinting in this region
  • Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal dominant inheritance pattern requiring maternal transmission for full penetrance.

Compare Similar Items

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Img

Thermo Scientific

PIPA596354

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Antigen:
GNAS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
5530400H20Rik, A930027G11Rik, Adenylate cyclase-stimulating G alpha protein, AHO, ALEX, GNAS, NESP55, alpha-stimulatory subunit of GTP-binding protein, alternative gene product encoded by XL-exon, C130027O20Rik, C20orf45, dJ309F20.1.1, dJ806M20.3.3, Extra large alphas protein, G protein alpha subunit, G protein subunit alpha S, GAIPIRRH peptide, G-alpha-8, Galphas, Gnas, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, gnas {ECO:0000312, GNAS complex locus, GNAS complex locus, SCG6 (secretogranin VI), GNAS1, Gnasxl, Gnpas, GPIPIRRH peptide, GPSA, Gs alpha subunit, GSA, G-SALPHA60A, GSP, GTP-binding regulatory protein (G-s-alpha)., GTP-binding regulatory protein alpha subunit exon 1, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1, guanine nucleotide binding protein alpha s, guanine nucleotide binding protein alpha subunit, guanine nucleotide binding protein, alpha stimulating activity polypeptide 1, guanine nucleotide

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14683, 24896, 2778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
2.14 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1

Gene Symbols:
GNAS

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAS (NP_0005071)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596355

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Antigen:
HAX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hax1

Gene Alias:
FLJ17042, FLJ18492, FLJ93803, Hax1, HAX-1, HCLS1 (and PKD2) associated protein, HCLS1 associated protein X-1, HCLS1 associated X-1, HCLS1-associated protein X-1, HCLSBP1, HS1 binding protein, HS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1, HSP1BP-1, mHAX-1s, OTTHUMP00000034190, RP11-137P24.1, SCN3, SIG-111, Silg111

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10456, 23897, 291202

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O00165, O35387, Q7TSE9

Gene Symbols:
Hax1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human HAX1 (NP_0061092)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596357

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Antigen:
PNMT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pnmt

Gene Alias:
Noradrenaline N-methyltransferase, PENT, phenylethanolamine N-methylase, phenylethanolamine N-methyltransferase, phenylethanolamine-N-methyltransferase, PNMT, PNMTase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18948, 5409

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.77 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P11086, P40935

Gene Symbols:
Pnmt

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human PNMT (NP_0026771)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596358

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Antigen:
PSMF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSMF1

Gene Alias:
AW048666, BC012260, hPI31, PI31, proteasome (prosome, macropain) inhibitor subunit 1, proteasome (prosome, macropain) inhibitor subunit 1 (PI31), proteasome inhibitor PI31 subunit, proteasome inhibitor subunit 1, PSMB2, Psmf1, RP23 402M7.5, RP4 545L17.1, RP4-545L17.1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228769, 689852, 9491

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q5XIU5, Q8BHL8, Q92530

Gene Symbols:
PSMF1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human PSMF1 (NP_0068052)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG