PIPA596361

RNF2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA596361-Each-of-1 In Stock ₹ 44,705.10

PIPA596361 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RNF2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RNF2

Gene Alias

AI326319, AI450156, AU019207, BAP 1, BAP1, BAP-1, DinG, DinG protein, E3 ubiquitin-protein ligase RING2, fa19h05, GS1-120K12.1, HIP2-interacting protein 3, HIPI 3, HIPI3, Huntingtin-interacting protein 2-interacting protein 3, OTTHUMP00000060668, protein DinG, RING 1B, RING 2, RING finger protein 1B, ring finger protein 2, RING finger protein BAP-1, RING1B, RING2, RING-type E3 ubiquitin transferase RING2, RNF 2, Rnf2, wu:fa19h05, wz4556, wz4566

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19821, 304850, 6045

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.69 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

Q4KLY4, Q99496, Q9CQJ4

Gene Symbols

RNF2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RING1B/RING1B/RNF2 (NP_0091431)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: MSQAVQTNGT QPLSKTWELS LYELQRTPQE AITDGLEIVV SPRSLHSELM CPICLDMLKN TMTTKECLHR FCADCIITAL RSGNKECPTC RKKLVSKRSL RPDPNFDALI SKIYPSRDEY EAHQERVLAR INKHNNQQAL SHSIEEGLKI QAMNRLQRGK KQQIENGSGA EDNGDSSHCS NASTHSNQEA GPSNKRTKTS DDSGLELDNN NAAMAIDPVM DGASEIELVF RPHPTLMEKD DSAQTRYIKT SGNATVDHLS KYLAVRLALE ELRSKGESNQ MNLDTASEKQ YTIYIATASG QFTVLNGSFS LELVSEKYWK VNKPMELYYA PTKEHK; Positive Samples: 293T, Jurkat, U-937, SH-SY5Y, Mouse brain, Mouse spleen; Cellular Location: Chromosome, Nucleus RNF2 (E3 ubiquitin-protein ligase RING2) is a ligase that mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub)
  • Therefore, it plays a central role in histone code and gene regulation
  • The ligase activity is enhanced by BMI1/PCGF4
  • H2AK119Ub gives a specific tag for epigeneti transcriptional repression and participates in X chromosome inactivation of female mammals
  • RNF2 may be involved in the initiation of both imprinted and random X inactivation
  • RNF2 is also an essential component of a Polycomb group (PcG) multiprotein PRC1-like complex
  • This complex class is required to maintain the transcriptionally repressive state of many genes including Hox genes throughout development
  • The PcG PRC1 complex acts via chromatin remodeling and modification of histones and rendering chromatin heritably changed in its expressibility.

Compare Similar Items

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Img

Thermo Scientific

PIPA596361

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Antigen:
RNF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF2

Gene Alias:
AI326319, AI450156, AU019207, BAP 1, BAP1, BAP-1, DinG, DinG protein, E3 ubiquitin-protein ligase RING2, fa19h05, GS1-120K12.1, HIP2-interacting protein 3, HIPI 3, HIPI3, Huntingtin-interacting protein 2-interacting protein 3, OTTHUMP00000060668, protein DinG, RING 1B, RING 2, RING finger protein 1B, ring finger protein 2, RING finger protein BAP-1, RING1B, RING2, RING-type E3 ubiquitin transferase RING2, RNF 2, Rnf2, wu:fa19h05, wz4556, wz4566

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19821, 304850, 6045

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.69 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
Q4KLY4, Q99496, Q9CQJ4

Gene Symbols:
RNF2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RING1B/RING1B/RNF2 (NP_0091431)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596362

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Antigen:
WNK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WNK3

Gene Alias:
KIAA1566, PRKWNK 3, PRKWNK3, Protein kinase lysine-deficient 3, protein kinase with no lysine 3, RGD1563131, serine/threonine-protein kinase WNK3, WNK 3, WNK lysine deficient protein kinase 3, WNK lysine deficient protein kinase 3, pseudogene, WNK3, Wnk3-ps

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
279561, 317420, 65267

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.98 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q80XP9, Q9BYP7

Gene Symbols:
WNK3

Immunogen:
Recombinant protein of rat WNK3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596363

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Antigen:
SKIV2L2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTREX

Gene Alias:
2610528A15Rik, ATP-dependent helicase SKIV2L2, ATP-dependent RNA helicase DOB1, ATP-dependent RNA helicase SKIV2L2, Dob1, Exosome RNA helicase MTR4, exosome RNA helicase MTR4, superkiller viralicidic activity 2-like 2, fSAP118, functional spliceosome-associated protein 118, KIAA0052, mKIAA0052, Mtr4, Mtr4 exosome RNA helicase, MTREX, RGD1305984, Ski2 like RNA helicase 2, SKIV2L2, Superkiller viralicidic activity 2-like 2, superkiller viralicidic activity 2-like 2 (S. cerevisiae), superkiller viralicidic activity 2-like 2-like, TRAMP-like complex helicase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23517, 72198

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.58 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P42285, Q9CZU3

Gene Symbols:
MTREX

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_0561753)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA596364

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Antigen:
FUBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FUBP1

Gene Alias:
9530027K12Rik, D3Ertd330e, DNA helicase V, EMBL:AAI07943.1, ECO:0000312, EMBL:AAI07943.1}, far upstream element (FUSE) binding protein 1, far upstream element (FUSE) binding protein 4, far upstream element binding protein 1, far upstream element-binding protein, far upstream element-binding protein 1, far upstream element-binding protein 1 {ECO:0000250, FBP, FBP {ECO:0000250, Fubp, Fubp1, fubp1 {ECO:0000312, Fubp4, FUSE binding protein 1, FUSE-binding protein 1, FUSE-binding protein 1 {ECO:0000250, hDH V, RGD:1591892}, UniProtKB:Q96AE4, ECO:0000312, UniProtKB:Q96AE4}

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51886, 654496, 8880

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.74 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q32PX7, Q91WJ8, Q96AE4

Gene Symbols:
FUBP1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 302-644 of human FUBP1 (NP_0038932)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG