PIPA596474
ATM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596474-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA596474 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ATM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1900-2000 of human ATM (NP_0000423)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: CLDKKSQRTM LAVVDYMRRQ KRPSSGTIFN DAFWLDLNYL EVAKVAQSCA AHFTALLYAE IYADKKSMDD QEKRSLAFEE GSQSTTISSL SEKSKEETGI S; Positive Samples: NCI-H460; Cellular Location: Cytoplasmic vesicle, Nucleus Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: ATM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 472
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1900-2000 of human ATM (NP_0000423)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
472
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1900-2000 of human ATM (NP_0000423)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: eRF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ETF1
Gene Alias: AI463371, D5S1995, D6Ertd109e, ERF, ERF1, ETF1, Eukaryotic peptide chain release factor subunit 1, eukaryotic release factor 1, eukaryotic translation termination factor 1, polypeptide chain release factor 1, protein Cl1, RF1, sup45 (yeast omnipotent suppressor 45) homolog-like 1, SUP45L1, TB3-1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2107, 225363, 307503
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2.24 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P62495, Q5U2Q7, Q8BWY3
Gene Symbols: ETF1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 278-437 of human ETF1 (NP_0047211)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
eRF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ETF1
Gene Alias:
AI463371, D5S1995, D6Ertd109e, ERF, ERF1, ETF1, Eukaryotic peptide chain release factor subunit 1, eukaryotic release factor 1, eukaryotic translation termination factor 1, polypeptide chain release factor 1, protein Cl1, RF1, sup45 (yeast omnipotent suppressor 45) homolog-like 1, SUP45L1, TB3-1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2107, 225363, 307503
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2.24 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P62495, Q5U2Q7, Q8BWY3
Gene Symbols:
ETF1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 278-437 of human ETF1 (NP_0047211)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FUS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FUS
Gene Alias: 16) in malignant liposarcoma), 16) malignant liposarcoma, 75 kDa DNA-pairing protein, ALS6, D430004D17Rik, D930039C12Rik, ETM4, FUS, FUS RNA binding protein, Fus1, fused in sarcoma, fused in sarcoma RNA binding protein, fusion (involved in t(12, fusion gene in myxoid liposarcoma, fusion, derived from t(12, fusion, derived from t(12;16) malignant liposarcoma, fus-like protein, heterogeneous nuclear ribonucleoprotein P2, hnRNP P2, HNRNPP2, oncogene FUS, Oncogene TLS, pigpen protein, POMP75, Protein pigpen, RNA-binding protein FUS, TLS, translocated in liposarcoma, translocated in liposarcoma protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 233908, 2521, 317385
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot
Concentration: 0.82 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P35637, P56959
Gene Symbols: FUS
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_0049511)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FUS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FUS
Gene Alias:
16) in malignant liposarcoma), 16) malignant liposarcoma, 75 kDa DNA-pairing protein, ALS6, D430004D17Rik, D930039C12Rik, ETM4, FUS, FUS RNA binding protein, Fus1, fused in sarcoma, fused in sarcoma RNA binding protein, fusion (involved in t(12, fusion gene in myxoid liposarcoma, fusion, derived from t(12, fusion, derived from t(12;16) malignant liposarcoma, fus-like protein, heterogeneous nuclear ribonucleoprotein P2, hnRNP P2, HNRNPP2, oncogene FUS, Oncogene TLS, pigpen protein, POMP75, Protein pigpen, RNA-binding protein FUS, TLS, translocated in liposarcoma, translocated in liposarcoma protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
233908, 2521, 317385
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot
Concentration:
0.82 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P35637, P56959
Gene Symbols:
FUS
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_0049511)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RPL10A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RPL10A
Gene Alias: 60S ribosomal protein L10a, CSA19, Csa-19, L10A, Large ribosomal subunit protein uL1, Nedd6, NEDD-6, Neural precursor cell expressed developmentally down-regulated protein 6, ribosomal protein L10a, RPL10A, Unknown (protein for MGC:73082), wu:fb94f08, zgc:73082, zgc:86881
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19896, 4736, 81729
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P53026, P62906, P62907
Gene Symbols: RPL10A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human RPL10A (NP_0090353)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RPL10A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RPL10A
Gene Alias:
60S ribosomal protein L10a, CSA19, Csa-19, L10A, Large ribosomal subunit protein uL1, Nedd6, NEDD-6, Neural precursor cell expressed developmentally down-regulated protein 6, ribosomal protein L10a, RPL10A, Unknown (protein for MGC:73082), wu:fb94f08, zgc:73082, zgc:86881
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19896, 4736, 81729
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P53026, P62906, P62907
Gene Symbols:
RPL10A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human RPL10A (NP_0090353)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG