PIPA596763
JAK2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596763-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA596763 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
JAK2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
JAK2
Gene Alias
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16452, 24514, 3717
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.31 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
O60674, Q62120, Q62689
Gene Symbols
JAK2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 933-1132 of human JAK2 (NP_0049631)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: MCF7, Jurkat, Mouse liver; Cellular Location: Cytoplasm, Endomembrane system, Nucleus, Peripheral membrane protein Immunogen sequence: PYGSLRDYLQ KHKERIDHIK LLQYTSQICK GMEYLGTKRY IHRDLATRNI LVENENRVKI GDFGLTKVLP QDKEYYKVKE PGESPIFWYA PESLTESKFS VASDVWSFGV VLYELFTYIE KSKSPPAEFM RMIGNDKQGQ MIVFHLIELL KNNGRLPRPD GCPDEIYMIM TECWNNNVNQ RPSFRDLALR VDQIRDNMAG Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
- This kinase contains the catalytic domain (JH1) of JAK2
- The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
- Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
- JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
- Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
- Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.
Compare Similar Items
Show Difference
Antigen: JAK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JAK2
Gene Alias: EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16452, 24514, 3717
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.31 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O60674, Q62120, Q62689
Gene Symbols: JAK2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 933-1132 of human JAK2 (NP_0049631)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
JAK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JAK2
Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16452, 24514, 3717
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.31 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O60674, Q62120, Q62689
Gene Symbols:
JAK2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 933-1132 of human JAK2 (NP_0049631)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LOX
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LOX
Gene Alias: AI893619, cross-linking enzyme, H-rev142, LOX, Lysyl oxidase, Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts), MGC105112, protein-lysine 6-oxidase, Protein-lysine 6-oxidase, long form, Protein-lysine 6-oxidase, short form, Ras excision protein, ras recision, rrg, Rrg1, TSC-160
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16948, 24914, 4015
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.62 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P16636, P28300, P28301
Gene Symbols: LOX
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human LOX (NP_0023082)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LOX
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LOX
Gene Alias:
AI893619, cross-linking enzyme, H-rev142, LOX, Lysyl oxidase, Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts), MGC105112, protein-lysine 6-oxidase, Protein-lysine 6-oxidase, long form, Protein-lysine 6-oxidase, short form, Ras excision protein, ras recision, rrg, Rrg1, TSC-160
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16948, 24914, 4015
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.62 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P16636, P28300, P28301
Gene Symbols:
LOX
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human LOX (NP_0023082)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: YBX1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: YBX1
Gene Alias: 1700102N10Rik, BP8, BP-8, Byb1, C79409, Cbfa, CBF-A, CCAAT-binding, CCAAT-binding transcription factor 1 subunit A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, dbpB, DNA binding protein B, DNA-binding protein B, EF1A, EFI-A, enhancer factor 1 alpha, enhancer factor 1 subunit A, enhancer factor I subunit A, major histocompatibility complex, class II, Y box-binding protein I, MDR NF1, MDR-NF1, MGC104858, MGC110976, MGC117250, Msy1, Msy-1, mYB-1a, Nsep1, NSEP-1, nuclease sensitive element binding protein 1, nuclease-sensitive element-binding protein 1, Y box binding protein 1, Y box protein 1, Y box transcription factor, YB1, YB-1, Y-box binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YBX1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22608, 4904, 500538
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.22 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P62960, P62961, P67809
Gene Symbols: YBX1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human YB-1/YB-1/YBX1 (NP_0045502)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
YBX1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
YBX1
Gene Alias:
1700102N10Rik, BP8, BP-8, Byb1, C79409, Cbfa, CBF-A, CCAAT-binding, CCAAT-binding transcription factor 1 subunit A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, dbpB, DNA binding protein B, DNA-binding protein B, EF1A, EFI-A, enhancer factor 1 alpha, enhancer factor 1 subunit A, enhancer factor I subunit A, major histocompatibility complex, class II, Y box-binding protein I, MDR NF1, MDR-NF1, MGC104858, MGC110976, MGC117250, Msy1, Msy-1, mYB-1a, Nsep1, NSEP-1, nuclease sensitive element binding protein 1, nuclease-sensitive element-binding protein 1, Y box binding protein 1, Y box protein 1, Y box transcription factor, YB1, YB-1, Y-box binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YBX1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22608, 4904, 500538
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.22 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P62960, P62961, P67809
Gene Symbols:
YBX1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human YB-1/YB-1/YBX1 (NP_0045502)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PGD
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PGD
Gene Alias: 0610042A05Rik, 6PGD, 6-phosphogluconate dehydrogenase, decarboxylating, 6-phosphogluconate dehydrogenase, decarboxylating-like, AU019875, C78335, LOC100360180, Pgd, PGDH, phosphogluconate dehydrogenase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100360180, 110208, 5226
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P52209, P85968, Q9DCD0
Gene Symbols: PGD
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 184-483 of human PGD (NP_0026222)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PGD
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PGD
Gene Alias:
0610042A05Rik, 6PGD, 6-phosphogluconate dehydrogenase, decarboxylating, 6-phosphogluconate dehydrogenase, decarboxylating-like, AU019875, C78335, LOC100360180, Pgd, PGDH, phosphogluconate dehydrogenase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100360180, 110208, 5226
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P52209, P85968, Q9DCD0
Gene Symbols:
PGD
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 184-483 of human PGD (NP_0026222)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG