PIPA596827

TSEN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596827-Each-of-1 In Stock ₹ 44,705.10

PIPA596827 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TSEN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tsen2

Gene Alias

AU067695, HsSen2, PCH2B, RGD1309946, SEN2, SEN2L, tRNA splicing endonuclease 2 homolog (S. cerevisiae), tRNA splicing endonuclease subunit 2, tRNA-intron endonuclease Sen2, tRNA-intron nuclease 2, tRNA-splicing endonuclease subunit Sen2, Tsen2, TSEN2 tRNA splicing endonuclease subunit

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

312649, 381802, 80746

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.11 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q5M954, Q6P7W5, Q8NCE0

Gene Symbols

Tsen2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TSEN2 (NP_0795411)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MAEAVFHAPK RKRRVYETYE SPLPIPFGQD HGPLKEFKIF RAEMINNNVI VRNAEDIEQL YGKGYFGKGI LSRSRPSFTI SDPKLVAKWK DMKTNMPIIT SKRYQHSVEW AAELMRRQGQ DESTVRRILK DYTKPLEHPP VKRNEEAQVH DKLNSGMVSN MEGTAGGERP SVVNGDSGKS GGVGDPREPL GCLQEGSGCH PTTESFEKSV REDASPLPHV; Positive Samples: MCF-7, HeLa, A-549, Mouse heart, Mouse brain, Rat heart; Cellular Location: Nucleus, nucleolus Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA
  • It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron
  • The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini
  • There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body
  • Isoform 1 probably carries the active site for 5'-splice site cleavage
  • The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre- mRNA 3'-end processing factors, establishing a link between pre- tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events
  • Isoform 2 is responsible for processing a yet unknown RNA substrate
  • The complex containing isoform 2 is not able to cleave pre-tRNAs properly, although it retains endonucleolytic activity.

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Show Difference

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PIPA596827

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Antigen:
TSEN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tsen2

Gene Alias:
AU067695, HsSen2, PCH2B, RGD1309946, SEN2, SEN2L, tRNA splicing endonuclease 2 homolog (S. cerevisiae), tRNA splicing endonuclease subunit 2, tRNA-intron endonuclease Sen2, tRNA-intron nuclease 2, tRNA-splicing endonuclease subunit Sen2, Tsen2, TSEN2 tRNA splicing endonuclease subunit

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
312649, 381802, 80746

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.11 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q5M954, Q6P7W5, Q8NCE0

Gene Symbols:
Tsen2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TSEN2 (NP_0795411)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596829

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Antigen:
CHRFAM7A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHRFAM7A

Gene Alias:
alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid, alpha-7 nicotinic cholinergic receptor subunit, CHRFAM7A, CHRNA7, CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion, CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion, CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion, CHRNA7-DR1, CHRNA7-FAM7A fusion protein, D-10, NACHRA7, Neuronal acetylcholine receptor subunit alpha-7

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89832

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q494W8

Gene Symbols:
CHRFAM7A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_6475361)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596831

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Antigen:
PHF21B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PHF21B

Gene Alias:
A730032D07Rik, BHC80L, KIAA1661, PHD finger protein 21B, PHD finger protein 4, PHF21B, PHF4, RGD1308739

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112885, 271305, 300117

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.09 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q8C966, Q96EK2

Gene Symbols:
PHF21B

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 322-531 of human PHF21B (NP_6124241)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596832

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Antigen:
LRG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRG1

Gene Alias:
1300008B03Rik, 2310031E04Rik, A2GL, HMFT1766, leucine rich alpha 2 glycoprotein, leucine rich alpha-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein, leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor, LRG, LRG 1, LRG1, LRG-1, Lrhg

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116844, 367455, 76905

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P02750

Gene Symbols:
LRG1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 36-347 of human LRG1 (NP_4432041)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG