PIPA596839

ADAR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596839-Each-of-1 In Stock ₹ 44,277.30

PIPA596839 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

ADAR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Adar

Gene Alias

136 kDa double-stranded RNA-binding protein, ADA, Adar, ADAR1, Adar1p110, Adar1p150, Adenosine Deaminase, adenosine deaminase acting on RNA 1-A, adenosine deaminase RNA specific, adenosine deaminase, RNA specific, adenosine deaminase, RNA-specific, AGS6, AV242451, double-stranded RNA-specific adenosine deaminase, DRADA, DSH, DSRAD, dsRNA adenosine deaminase, dsRNA adeonosine deaminase, G1P1, IFI4, IFI-4, interferon-induced protein 4, interferon-inducible protein 4, K88DSRBP, LOW QUALITY PROTEIN: double-stranded RNA-specific adenosine deaminase, mZaADAR, P136, RNA adenosine deaminase 1, RNA-specific adenosine deaminase p110 form, RNA-specific adenosine deaminase p150 form

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

103, 56417, 81635

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.46 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P55265, P55266, Q99MU3

Gene Symbols

Adar

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-299 of human ADAR11 (NP_0011022)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: U-87MG, A549, DU145, HeLa, HepG2; Cellular Location: Cytoplasm, Nucleus, Nucleus, nucleolus Immunogen sequence: RPDGHSQGAP NSDPSLE Adenosine Deaminase RNA Specific (ADAR) catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing.This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions
  • ADAR can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing)
  • Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2) and serotonin (HTR2C) and GABA receptor (GABRA3)
  • Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alters their functional activities
  • Exhibits low-level editing at the GRIA2 Q/R site, but edits efficiently at the R/G site and HOTSPOT1
  • Its viral RNA substrates include: hepatitis C virus (HCV), vesicular stomatitis virus (VSV), measles virus (MV), hepatitis delta virus (HDV), and human immunodeficiency virus type 1 (HIV-1)
  • Exhibits either a proviral (HDV, MV, VSV and HIV-1) or an antiviral effect (HCV) and this can be editing-dependent (HDV and HCV), editing-independent (VSV and MV) or both (HIV-1)
  • Impairs HCV replication via RNA editing at multiple sites
  • Enhances the replication of MV, VSV and HIV-1 through an editing-independent mechanism via suppression of EIF2AK2/PKR activation and function
  • Stimulates both the release and infectivity of HIV-1 viral particles by an editing-dependent mechanism where it associates with viral RNAs and edits adenosines in the 5'UTR and the Rev and Tat coding sequence
  • Can enhance viral replication of HDV via A-to-I editing at a site designated as amber/W, thereby changing an UAG amber stop codon to an UIG tryptophan (W) codon that permits synthesis of the large delta antigen (L-HDAg) which has a key role in the assembly of viral particles
  • However, high levels of ADAR1 inhibit HDV replication
  • (Uniprot)

Compare Similar Items

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Thermo Scientific

PIPA596839

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Antigen:
ADAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adar

Gene Alias:
136 kDa double-stranded RNA-binding protein, ADA, Adar, ADAR1, Adar1p110, Adar1p150, Adenosine Deaminase, adenosine deaminase acting on RNA 1-A, adenosine deaminase RNA specific, adenosine deaminase, RNA specific, adenosine deaminase, RNA-specific, AGS6, AV242451, double-stranded RNA-specific adenosine deaminase, DRADA, DSH, DSRAD, dsRNA adenosine deaminase, dsRNA adeonosine deaminase, G1P1, IFI4, IFI-4, interferon-induced protein 4, interferon-inducible protein 4, K88DSRBP, LOW QUALITY PROTEIN: double-stranded RNA-specific adenosine deaminase, mZaADAR, P136, RNA adenosine deaminase 1, RNA-specific adenosine deaminase p110 form, RNA-specific adenosine deaminase p150 form

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
103, 56417, 81635

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.46 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P55265, P55266, Q99MU3

Gene Symbols:
Adar

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-299 of human ADAR11 (NP_0011022)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596840

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Antigen:
ALDH9A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALDH9A1

Gene Alias:
4-trimethylaminobutyraldehyde dehydrogenase, 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed, AA139417, Abaldh, aldehyde dehydrogenase (NAD+), aldehyde dehydrogenase 9 family member A1, aldehyde dehydrogenase 9 family, member A1, aldehyde dehydrogenase 9, subfamily A1, aldehyde dehydrogenase 9A1, aldehyde dehydrogenase E3 isozyme, Aldehyde dehydrogenase family 9 member A1, aldehyde dehydrogenase family 9, subfamily A1, ALDH4, ALDH7, ALDH9, Aldh9a1, E3, ESTM40, gamma-aminobutyraldehyde dehydrogenase, gamma-trimethylaminobutyraldehyde dehydrogenase, R-aminobutyraldehyde dehydrogenase, TMABADH, TMABA-DH

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
223, 56752, 64040

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.49 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P49189, Q9JLJ2, Q9JLJ3

Gene Symbols:
ALDH9A1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALDH9A1 (NP_0006873)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA596841

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Antigen:
Angiopoietin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Angpt1

Gene Alias:
1110046O21Rik, 2810039D03Rik, AGP1, Agpt, Agpt1, ANG1, ang-1, ANG3, ANG-3, angioarrestin, angiopoietin 1, angiopoietin 3, angiopoietin like 1, angiopoietin Y1, angiopoietin-1, Angiopoietin-3, angiopoietin-like 1, angiopoietin-like protein 1, Angiopoietin-related protein 1, Angpt1, ANGPT3, Angptl1, AngY, ARP1, dJ595C2.2, dJ595C2.2 (angiopoietin Y1), endothelial growth factor, KIAA0003, PSEC0154, tie2 receptor ligand, UNQ162, UNQ162/PRO188

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11600, 284, 89807

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.62 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O08538, O35460, Q15389

Gene Symbols:
Angpt1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 277-498 of human ANGPT1 (NP_001137.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA596842

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Antigen:
ATP1A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP1A1

Gene Alias:
(Na+ + K+)-ATPase, (Na+, K+)-ATPase alpha-subunit, alpha subunit of sodium potassium ATPase, atp1a1, atp1a1-a, atp1a1a.4, atp1a1-b, ATP1B, Atpa-1, ATPase, ATPase Na+/K+ transporting subunit alpha 1, ATPase, Na+/K+ transporting, alpha 1 polypeptide, ATPase, Na+K+ transporting, alpha 1, BC010319, K-ATPase, MGC1798, Na(+)/K(+) ATPase alpha-1 subunit, Na, K-ATPase alpha-1 subunit, Na, K-ATPase, alpha-A catalytic polypeptide, Na,K-ATPase alpha-1 subunit, Na,K-ATPase catalytic subunit alpha-A protein, Na/K ATPase alpha 1 isoform, Na/K ATPase alpha 1 subunit, Na+ ,K+ -ATPase alpha subunit, Na+ /K+ ATPase alpha 1 subunit, Na+, K+-ATPase beta-subunit precursor, Na+/K+ ATPase, Na+/K+ ATPase 1, Na+/K+ ATPase Alpha, Na+/K+ -ATPase alpha 1 subunit, Na+/K+ transporting alpha 1 polypeptide, Na+K+ ATPase, Na+K+ATPase, Nkaa1b, RP4-655J12.1, sarcolemmal sodium/potassium-ATPase alpha 1, Sodium Potassium ATPase, sodium pump 1, sodium pump subunit alpha-1, sodium/potassium-ATPase alpha-subunit 1, sodium/potassium-transporting ATPase alpha-1 chain, sodium/potassium-transporting ATPase subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-1, sodium-potassium-ATPase, alpha 1 polypeptide, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11928, 24211, 476

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.44 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P05023, P06685, Q8VDN2

Gene Symbols:
ATP1A1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Na+/K+-ATPase (NP_0006922)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG