PIPA596906
MYLK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596906-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA596906 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MYLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MYLK
Gene Alias
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
107589, 288057, 4638
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.31 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q15746, Q6PDN3
Gene Symbols
MYLK
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_4442533)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SGLSGRKSST GSPTSPLNAE KLESEEDVSQ AFLEAVAEEK PHVKPYFSKT IRDLEVVEGS AARFDCKIEG YPDPEVVWFK DDQSIRESRH FQIDYDEDGN CSLIISDVCG DDDAKYTCKA VNSLGEATCT AELIVETMEE GEGEGEEEEE; Positive Samples: HeLa, HepG2, HT-1080; Cellular Location: Cell projection, Cleavage furrow, Cytoplasm, cytoskeleton, lamellipodium MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction)
- MLCK is responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments
- It is a central determinant in the development of vascular permeability and tissue edema formation
- In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells
- MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis
- Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific
- Non-muscle isoform 2 is the dominant splice variant expressed in various tissues
- The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues
- MLCK is probably down-regulated by phosphorylation
- The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.
Compare Similar Items
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Antigen: MYLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYLK
Gene Alias: 155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107589, 288057, 4638
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.31 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q15746, Q6PDN3
Gene Symbols: MYLK
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_4442533)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MYLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYLK
Gene Alias:
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107589, 288057, 4638
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.31 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q15746, Q6PDN3
Gene Symbols:
MYLK
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_4442533)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CCR8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCR8
Gene Alias: C-C, CC chemokine receptor 8, CC chemokine receptor CHEMR1, C-C chemokine receptor type 8, C-C CKR-8, C-C motif chemokine receptor 8, CC-chemokine receptor chemr1, CC-CKR-8, CCR8, CCR-8, cd198, CDw198, chemokine (C-C motif) receptor 8, chemokine (C-C) receptor 8, chemokine (C-C) receptor-like 2, chemokine receptor-like 1, CKR-8, CKRL1, CKR-L1, Cmkbr8, CMKBRL2, CY6, GPRCY6, GPR-CY6, mCCR8, MGC129966, MGC129973, TER1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12776, 301066
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P56484
Gene Symbols: CCR8
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 296-355 of human CCR8 (NP_0051921)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CCR8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCR8
Gene Alias:
C-C, CC chemokine receptor 8, CC chemokine receptor CHEMR1, C-C chemokine receptor type 8, C-C CKR-8, C-C motif chemokine receptor 8, CC-chemokine receptor chemr1, CC-CKR-8, CCR8, CCR-8, cd198, CDw198, chemokine (C-C motif) receptor 8, chemokine (C-C) receptor 8, chemokine (C-C) receptor-like 2, chemokine receptor-like 1, CKR-8, CKRL1, CKR-L1, Cmkbr8, CMKBRL2, CY6, GPRCY6, GPR-CY6, mCCR8, MGC129966, MGC129973, TER1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12776, 301066
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P56484
Gene Symbols:
CCR8
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 296-355 of human CCR8 (NP_0051921)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MR1
Gene Alias: Class I histocompatibility antigen-like protein, H2ls, histocompatibility-2 complex class 1-like sequence, Hlals, Major histocompatibility complex class I-related gene protein, major histocompatibility complex, class I-like sequence, major histocompatibility complex, class I-related, MCH class I, MHC class I-like antigen MR-1, MHC class I-like sequence, MHC class I-related gene protein, MHC class-I related-gene protein, MR1, Mr1a
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15064, 25119, 3140
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.42 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O19477, Q8HWB0, Q95460
Gene Symbols: MR1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-291 of human MR1 (NP_0015221)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MR1
Gene Alias:
Class I histocompatibility antigen-like protein, H2ls, histocompatibility-2 complex class 1-like sequence, Hlals, Major histocompatibility complex class I-related gene protein, major histocompatibility complex, class I-like sequence, major histocompatibility complex, class I-related, MCH class I, MHC class I-like antigen MR-1, MHC class I-like sequence, MHC class I-related gene protein, MHC class-I related-gene protein, MR1, Mr1a
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15064, 25119, 3140
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O19477, Q8HWB0, Q95460
Gene Symbols:
MR1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-291 of human MR1 (NP_0015221)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HMGCL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMGCL
Gene Alias: 3-hydroxy-3-methylglutarate-CoA lyase, 3-hydroxy-3-methylglutaryl-CoA lyase, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase, AW476067, HL, Hmgcl, HMG-CoA lyase, hydroxymethylglutaricaciduria, hydroxymethylglutaryl-CoA lyase, mitochondrial, mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15356, 3155, 79238
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.14 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P35914, P38060, P97519
Gene Symbols: HMGCL
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_0001822)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HMGCL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMGCL
Gene Alias:
3-hydroxy-3-methylglutarate-CoA lyase, 3-hydroxy-3-methylglutaryl-CoA lyase, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase, AW476067, HL, Hmgcl, HMG-CoA lyase, hydroxymethylglutaricaciduria, hydroxymethylglutaryl-CoA lyase, mitochondrial, mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15356, 3155, 79238
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.14 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P35914, P38060, P97519
Gene Symbols:
HMGCL
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_0001822)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG