PIPA596933

Complement C5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596933-Each-of-1 In Stock ₹ 44,619.54

PIPA596933 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

Complement C5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C5

Gene Alias

anaphylatoxin, anaphylatoxin C5, anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5, C5a, C5a anaphylatoxin, C5b, C5D, Complement C5, Complement C5 alpha chain, Complement C5 alpha' chain, Complement C5 beta chain, complement component 5, CPAMD4, ECLZB, Hc, He, hemolytic complement, prepro-C5, RGD1561905

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15139, 362119, 727

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.57 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

P01031, P06684, P08650

Gene Symbols

C5, Hc

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1567-1676 of human C5/C5a (NP_001726.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SITVENVFVK YKATLLDIYK TGEAVAEKDS EITFIKKVTC TNAELVKGRQ YLIMGKEALQ IKYNFSFRYI YPLDSLTWIE YWPRDTTCSS CQAFLANLDE FAEDIFLNGC; Positive Samples: U-937, Raji, Jurkat, Mouse heart, Rat liver C5 (Complement C5) is a Protein Coding gene
  • Diseases associated with C5 include Complement Component 5 Deficiency and Eculizumab, Poor Response To
  • Among its related pathways are GPCR downstream signalling and Acquired partial lipodystrophy / Barraquer-Simons syndrome
  • Gene Ontology (GO) annotations related to this gene include signaling receptor binding and endopeptidase inhibitor activity
  • An important paralog of this gene is C3
  • This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens
  • The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b
  • The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge
  • Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC)
  • Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections
  • Alternative splicing results in multiple transcript variants.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA596933

--


Antigen:
Complement C5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C5

Gene Alias:
anaphylatoxin, anaphylatoxin C5, anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5, C5a, C5a anaphylatoxin, C5b, C5D, Complement C5, Complement C5 alpha chain, Complement C5 alpha' chain, Complement C5 beta chain, complement component 5, CPAMD4, ECLZB, Hc, He, hemolytic complement, prepro-C5, RGD1561905

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15139, 362119, 727

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P01031, P06684, P08650

Gene Symbols:
C5, Hc

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1567-1676 of human C5/C5a (NP_001726.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA596934

--


Antigen:
CALCB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CALCB

Gene Alias:
Beta-CGRP, beta-type CGRP, CALC2, Calcb, calcitonin 2, calcitonin gene-related peptide 2, Calcitonin gene-related peptide II, calcitonin related polypeptide beta, calcitonin-related polypeptide beta, calcitonin-related polypeptide, beta, CGRP2, CGRP-II

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116903, 171519, 797

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
4.36 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P10092, P10093, Q99MP3

Gene Symbols:
CALCB

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human CALCB (NP_0007191)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA596935

--


Antigen:
CAPZB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CAPZB

Gene Alias:
1700120C01Rik, AI325129, Cap Z, CAPB, CAPPB, Cappb1, capping actin protein of muscle Z-line beta subunit, capping actin protein of muscle Z-line subunit beta, capping protein (actin filament) muscle Z-line, beta, capping protein beta 1, CAPZ, capZ beta, Capzb, CP beta1, CPB1, CPB2, CPbeat2, CPbeta1, CPbeta2, F-actin capping protein beta subunit, F-actin capping protein subunit beta 1, F-actin-capping protein subunit beta, MGC104401, MGC129749, MGC129750, RP4-657E11.7

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12345, 298584, 832

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
3.32 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P47756, P47757, Q5XI32

Gene Symbols:
CAPZB

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human CAPZB (NP_0049211)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA596938

--


Antigen:
Centrin 3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cetn3

Gene Alias:
CDC31, CDC31 yeast homolog, CEN3, centrin 3, centrin, EF-hand protein, 3, centrin, EF-hand protein, 3 (CDC31 homolog, yeast), centrin-3, Cetn3, EF-hand superfamily member, MmCEN3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1070, 12626, 170895

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O15182, O35648

Gene Symbols:
Cetn3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human CETN3 (NP_0043562)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG